Accutane and Vitamin e drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Accutane and Vitamin e. Common interactions include insomnia among females and inflammatory bowel disease among males.
The phase IV clinical study analyzes what interactions people who take Accutane and Vitamin e have. It is created by eHealthMe based on reports of 82 people who take Accutane and Vitamin e from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
82 people who take Accutane and Vitamin e together, and have interactions are studied.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 33,719 Accutane users for its effectiveness, alternative drugs and more.
What is Vitamin e?
Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 37,981 Vitamin e users for its effectiveness, alternative drugs and more.
Number of Accutane and Vitamin e reports submitted per year:

Common Accutane and Vitamin E drug interactions by gender *:
female:
- Insomnia
- Diarrhoea
- Fatigue
- Headache
- Diabetes mellitus
- Nausea
- Vision blurred
- Hepatocellular damage
- Panic attack
- Hallucination
male:
- Inflammatory bowel disease
- Crohn's disease
- Arthralgia
- Depression
- Intestinal haemorrhage
- Rectal haemorrhage
- Suicidal ideation
- Erythema nodosum
- Gastrointestinal disorder
- Limb discomfort
Common Accutane and Vitamin E drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Inflammatory bowel disease
- Crohn's disease
- Alopecia
- Intestinal haemorrhage
- Rectal haemorrhage
- Weight decreased
- Anaemia
- Erythema nodosum
- Fatigue
- Gastrointestinal disorder
20-29:
- Nausea
- Anxiety
- Epistaxis
- Headache
- Menstrual disorder
- Panic attack
- Vision blurred
- Convulsions
- Diabetes mellitus
- Diplopia
30-39:
- Paraesthesia
- Alanine aminotransferase increased
- Blood cholesterol increased
- Calculus ureteric
- Diarrhoea
- Difficulty in micturition
- Dysuria
- Endometriosis
- Fatigue
- Lip dry
40-49:
- White blood cell count increased
- Acute hepatic failure
- Adjustment disorder
- Alanine aminotransferase increased
- Amnesia
- Anaemia
- Anaphylactic reaction
- Arthralgia
- Arthritis
- Aspartate aminotransferase increased
50-59:
- Anal fistula
- Blood triglycerides increased
- Chapped lips
- Crohn's disease
- Haemoglobin decreased
- Inflammatory bowel disease
- Intestinal obstruction
- Iron deficiency anaemia
- Nausea
- Perirectal abscess
60+:
- Colitis ulcerative
- Depression
- Crohn's disease
- Headache
- Heart rate increased
- Inflammatory bowel disease
- Mood swings
- Nephrolithiasis
- Rash
- Adjustment disorder
* Approximation only. Some reports may have incomplete information.
Do you take Accutane and Vitamin e?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Accutane and Vitamin e interactions:
- Dry skin: 30 reports
- Depression: 24 reports
- Suicidal ideation: 22 reports
- Colitis (inflammation of colon): 13 reports
- Panic disorder: 6 reports
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 4 reports
Browse all drug interactions of Accutane and Vitamin e:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane side effects:
- Depression: 9,826 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9,190 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 7,519 reports
- Stress and anxiety: 5,193 reports
- Irritable bowel syndrome: 4,848 reports
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin e side effects:
- Fatigue (feeling of tiredness): 3,211 reports
- Diarrhea: 2,555 reports
- Weakness: 2,512 reports
- Drug ineffective: 2,443 reports
- Headache (pain in head): 2,361 reports
- Pain: 1,934 reports
- Dizziness: 1,889 reports
Browse all side effects of Vitamin e:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane interactions:
- Accutane and Ortho tri-cyclen: 1,116 reports
- Accutane and Prednisone: 639 reports
- Accutane and Profen: 446 reports
- Accutane and Ibuprofen: 445 reports
- Accutane and Tylenol: 422 reports
- Accutane and Retin-a: 351 reports
- Accutane and Advil: 315 reports
- Accutane and Zoloft: 313 reports
- Accutane and Yasmin: 266 reports
- Accutane and Cleocin: 258 reports
Browse all interactions between Accutane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Vitamin e interactions:
- Vitamin e and Vitamin d: 7,766 reports
- Vitamin e and Aspirin: 7,172 reports
- Vitamin e and Vitamin c: 6,540 reports
- Vitamin e and Calcium: 4,782 reports
- Vitamin e and Fish oil: 4,211 reports
- Vitamin e and Vitamin b12: 3,779 reports
- Vitamin e and Prednisone: 3,188 reports
- Vitamin e and Vitamin d3: 3,067 reports
- Vitamin e and Lipitor: 3,014 reports
- Vitamin e and Synthroid: 3,005 reports
Browse all interactions between Vitamin e and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isotretinoin and tocopherols and tocotrienols (the active ingredients of Accutane and Vitamin e, respectively), and Accutane and Vitamin e (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Accutane and Vitamin e.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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