Actrapid and Imodium drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 58 people who take Actrapid and Imodium. Common interactions include pleural effusion among females, and pyrexia among males.

The phase IV clinical study analyzes what interactions people who take Actrapid and Imodium have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 26, 2023

58 people who take Actrapid and Imodium together, and have interactions are studied.

What is Actrapid?

Actrapid has active ingredients of insulin. Currently, eHealthMe is studying from 4,687 Actrapid users.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is used in diarrhea. Currently, eHealthMe is studying from 42,387 Imodium users.

Number of Actrapid and Imodium reports submitted per year:

Actrapid and Imodium drug interactions.

Common Actrapid and Imodium drug interactions by gender *:


  1. Pleural effusion
  2. Transaminases increased
  3. Weight decreased
  4. Wound necrosis
  5. Blister
  6. Pruritus
  7. Hyperglycaemia
  8. Pyrexia
  9. Acute circulatory failure
  10. Stevens-johnson syndrome


  1. Pyrexia
  2. Eosinophil count increased
  3. Aspartate aminotransferase increased
  4. Asphyxia
  5. Asthenia
  6. Blood creatinine increased
  7. Diabetes mellitus inadequate control
  8. Febrile bone marrow aplasia
  9. Gastrointestinal disorder
  10. Nausea

Common Actrapid and Imodium drug interactions by age *:










  1. Mucosal erosion
  2. Mycosis fungoides
  3. Neutropenia
  4. Skin ulcer
  5. White blood cell count decreased
  6. Blood creatinine decreased
  7. Blood creatinine increased
  8. Burkitt's lymphoma
  9. Oral mucosal eruption
  10. Oral mucosal sloughing


  1. Eosinophil count increased
  2. Erythema
  3. Pyrexia
  4. Rash macular
  5. Tubulointerstitial nephritis
  6. Renal failure acute
  7. Aspartate aminotransferase increased
  8. Blood bilirubin increased
  9. Blood creatinine increased
  10. Cholestasis


  1. Hypomagnesaemia
  2. Torsade de pointes
  3. Ventricular fibrillation
  4. Blood creatinine increased
  5. Confusion
  6. Constipation
  7. Dehydration
  8. Dry mouth
  9. Febrile bone marrow aplasia
  10. Hyperkalaemia


  1. Abdominal pain
  2. Acute pulmonary oedema
  3. Diabetic foot
  4. Dyspnoea
  5. Gastric ulcer
  6. Hyperglycaemia
  7. Hyperkalaemia
  8. Hypokalaemia
  9. Hypothyroidism
  10. Malignant neoplasm progression

Common conditions people have *:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 16 people, 27.59%
  2. High Blood Pressure: 11 people, 18.97%
  3. Pain: 9 people, 15.52%
  4. Constipation: 8 people, 13.79%
  5. Diabetes: 8 people, 13.79%
  6. Itching: 7 people, 12.07%
  7. Type 2 Diabetes: 6 people, 10.34%
  8. Depression: 6 people, 10.34%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 10.34%
  10. Nausea (feeling of having an urge to vomit): 6 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Actrapid and Imodium?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drug side effects by duration, gender and age:

Common Actrapid drug interactions:

Browse interactions between Actrapid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Imodium drug interactions:

Browse interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on insulin and loperamide hydrochloride (the active ingredients of Actrapid and Imodium, respectively), and Actrapid and Imodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Actrapid and Imodium.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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