Adcirca and Uptravi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Adcirca and Uptravi. Common interactions include hypotension among females and diarrhoea among males.
The phase IV clinical study analyzes what interactions people who take Adcirca and Uptravi have. It is created by eHealthMe based on reports of 6,188 people who take Adcirca and Uptravi from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
6,188 people who take Adcirca and Uptravi together, and have interactions are studied.
What is Adcirca?
Adcirca has active ingredients of tadalafil. It is often used in pulmonary hypertension. eHealthMe is studying from 51,715 Adcirca users for its effectiveness, alternative drugs and more.
What is Uptravi?
Uptravi has active ingredients of selexipag. eHealthMe is studying from 22,190 Uptravi users for its effectiveness, alternative drugs and more.
Number of Adcirca and Uptravi reports submitted per year:

Adcirca and Uptravi drug interactions by gender *:
Adcirca and Uptravi drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Adcirca and Uptravi?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Adcirca and Uptravi interactions:
- Breathing difficulty: 1,216 reports
- Headache (pain in head): 869 reports
- Fatigue (feeling of tiredness): 673 reports
- Pain: 619 reports
- Dizziness: 603 reports
- Malaise (a feeling of general discomfort or uneasiness): 566 reports
- Nausea and vomiting: 415 reports
- Skin blushing/flushing (a sudden reddening of the face, neck): 304 reports
Browse all drug interactions of Adcirca and Uptravi:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Adcirca side effects:
- Breathing difficulty: 9,515 reports
- Headache (pain in head): 7,648 reports
- Diarrhea: 6,014 reports
- Death: 4,159 reports
- Fatigue (feeling of tiredness): 3,869 reports
- Dizziness: 3,782 reports
- Pneumonia: 3,682 reports
- Malaise (a feeling of general discomfort or uneasiness): 3,273 reports
Browse all side effects of Adcirca:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Uptravi side effects:
- Headache (pain in head): 7,340 reports
- Diarrhea: 5,641 reports
- Breathing difficulty: 5,339 reports
- Fatigue (feeling of tiredness): 2,871 reports
- Dizziness: 2,548 reports
- Muscle aches (muscle pain): 2,547 reports
- Pain: 2,507 reports
Browse all side effects of Uptravi:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Adcirca interactions:
- Adcirca and Letairis: 15,091 reports
- Adcirca and Ambrisentan: 10,966 reports
- Adcirca and Remodulin: 10,246 reports
- Adcirca and Opsumit: 9,480 reports
- Adcirca and Tyvaso: 7,560 reports
- Adcirca and Tracleer: 5,267 reports
- Adcirca and Coumadin: 4,532 reports
- Adcirca and Furosemide: 3,538 reports
- Adcirca and Orenitram: 3,190 reports
Browse all interactions between Adcirca and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Uptravi interactions:
- Uptravi and Opsumit: 8,784 reports
- Uptravi and Ambrisentan: 4,517 reports
- Uptravi and Adempas: 3,170 reports
- Uptravi and Letairis: 2,141 reports
- Uptravi and Furosemide: 2,021 reports
- Uptravi and Revatio: 1,730 reports
- Uptravi and Tadalafil: 1,686 reports
- Uptravi and Spironolactone: 1,437 reports
- Uptravi and Eliquis: 1,375 reports
Browse all interactions between Uptravi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tadalafil and selexipag (the active ingredients of Adcirca and Uptravi, respectively), and Adcirca and Uptravi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Adcirca and Uptravi.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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