Aldactone and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aldactone and Votrient. Common interactions include pyrexia among females and asthenia among males.

The phase IV clinical study analyzes what interactions people who take Aldactone and Votrient have. It is created by eHealthMe based on reports of 18 people who take Aldactone and Votrient from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Nov, 29, 2022

18 people who take Aldactone and Votrient together, and have interactions are studied.


What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 43,456 Aldactone users for its effectiveness, alternative drugs and more.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 24,021 Votrient users for its effectiveness, alternative drugs and more.

Number of Aldactone and Votrient reports submitted per year:

Aldactone and Votrient drug interactions.

Common Aldactone and Votrient drug interactions by gender *:

female:

  1. Pyrexia
  2. Acute sinusitis
  3. Diarrhoea
  4. Enteritis
  5. Haemoptysis
  6. Hypertriglyceridaemia
  7. Hypokalaemia
  8. Hyponatraemia
  9. Productive cough
  10. Nausea

male:

  1. Asthenia
  2. Diarrhoea
  3. Fatigue
  4. Dyspnoea
  5. Pyrexia
  6. Cough
  7. Death
  8. Discomfort
  9. Dysphagia
  10. Ecchymosis

Common Aldactone and Votrient drug interactions by age *:

0-1:

n/a

2-9:

  1. Cerebral haemorrhage
  2. Cholelithiasis
  3. Haemorrhage intracranial
  4. Headache
  5. Pyrexia
  6. Seizure
  7. Upper respiratory tract infection

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Nausea
  2. Vomiting
  3. Dehydration
  4. Hyperthyroidism
  5. Left ventricular dysfunction
  6. Oedema
  7. Asthenia
  8. Cough
  9. Death
  10. Discomfort

50-59:

  1. Cardiac failure

60+:

  1. Diarrhoea
  2. Pyrexia
  3. Nausea
  4. Dysgeusia
  5. Atrial fibrillation
  6. Decreased appetite
  7. Dyspnoea
  8. Fall
  9. Abdominal distension
  10. Ascites

Common conditions people have *:

  1. High Blood Pressure: 8 people, 44.44%
  2. Renal Cell Carcinoma (a kidney cancer): 8 people, 44.44%
  3. Pneumonia: 4 people, 22.22%
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 22.22%
  5. Overdose: 4 people, 22.22%
  6. Cough: 4 people, 22.22%
  7. Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 4 people, 22.22%
  8. Metastases To Lung (cancer spreads to lung): 4 people, 22.22%
  9. Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 2 people, 11.11%
  10. Synovial Sarcoma (tumour of synovial membrane of joint): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and Votrient?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Aldactone and Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Aldactone side effects:

Browse all side effects of Aldactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Votrient side effects:

Browse all side effects of Votrient:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Aldactone interactions:

Browse all interactions between Aldactone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Votrient interactions:

Browse all interactions between Votrient and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone and pazopanib hydrochloride (the active ingredients of Aldactone and Votrient, respectively), and Aldactone and Votrient (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Aldactone and Votrient.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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