Aldactone and Votrient drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aldactone and Votrient. Common interactions include pyrexia among females and asthenia among males.

The phase IV clinical study analyzes what interactions people who take Aldactone and Votrient have. It is created by eHealthMe based on reports of 18 people who take Aldactone and Votrient from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 29, 2022

18 people who take Aldactone and Votrient together, and have interactions are studied.

What is Aldactone?

Aldactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 43,456 Aldactone users for its effectiveness, alternative drugs and more.

What is Votrient?

Votrient has active ingredients of pazopanib hydrochloride. It is often used in metastatic renal cell carcinoma. eHealthMe is studying from 24,021 Votrient users for its effectiveness, alternative drugs and more.

Number of Aldactone and Votrient reports submitted per year:

Common Aldactone and Votrient drug interactions by gender *:

female:

Pyrexia
Acute sinusitis
Diarrhoea
Enteritis
Haemoptysis
Hypertriglyceridaemia
Hypokalaemia
Hyponatraemia
Productive cough
Nausea

male:

Asthenia
Diarrhoea
Fatigue
Dyspnoea
Pyrexia
Cough
Death
Discomfort
Dysphagia
Ecchymosis

Common Aldactone and Votrient drug interactions by age *:

0-1:

n/a

2-9:

Cerebral haemorrhage
Cholelithiasis
Haemorrhage intracranial
Headache
Pyrexia
Seizure
Upper respiratory tract infection

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Nausea
Vomiting
Dehydration
Hyperthyroidism
Left ventricular dysfunction
Oedema
Asthenia
Cough
Death
Discomfort

50-59:

Cardiac failure

60+:

Diarrhoea
Pyrexia
Nausea
Dysgeusia
Atrial fibrillation
Decreased appetite
Dyspnoea
Fall
Abdominal distension
Ascites

Common conditions people have *:

High Blood Pressure: 8 people, 44.44%
Renal Cell Carcinoma (a kidney cancer): 8 people, 44.44%
Pneumonia: 4 people, 22.22%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 4 people, 22.22%
Overdose: 4 people, 22.22%
Cough: 4 people, 22.22%
Malnutrition (condition that results from eating a diet in which certain nutrients are lacking): 4 people, 22.22%
Metastases To Lung (cancer spreads to lung): 4 people, 22.22%
Anaplastic Astrocytoma (tumour of the glial (supportive) tissue of the brain): 2 people, 11.11%
Synovial Sarcoma (tumour of synovial membrane of joint): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Aldactone and Votrient?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Costa DA, de Almeida SB, Barata PC, Quintela A, Cabral P, Afonso A, Silva JM, "Pazopanib-Induced Cutaneous Leukocytoclastic Vasculitis: An Exclusion Diagnosis of a Multidisciplinary Approach", Case Reports in Oncology, 2013 Jan .