Alendronate sodium and Prograf drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Alendronate sodium and Prograf together. This study is created by eHealthMe based on reports of 193 people who take Alendronate sodium and Prograf from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on alendronate sodium and tacrolimus (the active ingredients of Alendronate sodium and Prograf, respectively), and Alendronate sodium and Prograf (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Alendronate sodium?

Alendronate sodium has active ingredients of alendronate sodium. It is often used in osteoporosis. (latest outcomes from Alendronate sodium 27,033 users)

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. (latest outcomes from Prograf 34,483 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Feb, 25, 2019

193 people who take Alendronate sodium, Prograf are studied.


Number of reports submitted per year:

Alendronate sodium and Prograf drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Granulocytopenia (lack of granulocyte)
  2. Stomatitis (inflammation of mucous membrane of mouth)
  3. Vomiting
  4. Aphthous stomatitis (mouth ulcer)
  5. Cough
  6. Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
  7. Eating disorder
  8. Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
  9. Head injury
  10. Immunosuppressant drug level increased
1 - 6 months:
  1. Renal impairment (severely reduced kidney function)
  2. Aphthous stomatitis (mouth ulcer)
  3. Cough
  4. Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
  5. Eating disorder
  6. Gastric ulcer (stomach ulcer)
  7. Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
  8. Head injury
  9. Immunosuppressant drug level increased
  10. Interstitial lung disease
6 - 12 months:
  1. Constipation
  2. Pyrexia (fever)
  3. Thrombotic microangiopathy (a pathology that results in thrombosis in capillaries and arterioles, due to an endothelial injury)
  4. Upper respiratory tract inflammation
  5. Gastric ulcer (stomach ulcer)
  6. Histiocytosis haematophagic
  7. Hypertension (high blood pressure)
  8. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  9. Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
  10. Viral infection
1 - 2 years:
  1. Urinary retention (the inability to completely or partially empty the bladder)
  2. Drug level increased
  3. Intracranial hypotension (low pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
  4. Nephrotic syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema)
  5. Osteonecrosis (death of bone)
  6. Prostate cancer
  7. Pruritus (severe itching of the skin)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Anxiety disorder
  10. Death of relative
2 - 5 years:
  1. Klebsiella infection
  2. Legionella infection (a lung infection caused by bacteria of the species legionella)
  3. Leukoencephalopathy (disease of the white matter in the brain)
  4. Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
  5. Lung infection
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Meningitis cryptococcal (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  8. Meningitis tuberculous (a bacterial infection of the membranes covering the brain and spinal cord (meninges))
  9. Muscle spasms (muscle contraction)
  10. Obliterative bronchiolitis (bronchiolar inflammation)
5 - 10 years:
  1. Alopecia (absence of hair from areas of the body)
  2. Asthma
  3. Dyspepsia (indigestion)
  4. Gastritis (inflammation of stomach)
  5. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  6. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  7. Glossitis (infection of tongue with soreness)
  8. Headache (pain in head)
  9. Heart transplant rejection
  10. Herpes zoster
10+ years:

n/a

not specified:
  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Renal impairment (severely reduced kidney function)
  3. Upper respiratory tract inflammation
  4. Herpes zoster
  5. White blood cell count increased
  6. Influenza
  7. Oral candidiasis (fungal infection of mouth)
  8. Neoplasm skin (skin tumour)
  9. Periodontal disease (disease that attacks the gum and bone and around the teeth)
  10. Diarrhoea

Most common drug interactions by gender *:

female:
  1. Vomiting
  2. Nausea (feeling of having an urge to vomit)
  3. Osteonecrosis (death of bone)
  4. Decreased appetite
  5. Cardiac failure
  6. Dizziness
  7. Renal impairment (severely reduced kidney function)
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pneumonia
  10. Pruritus (severe itching of the skin)
male:
  1. Upper respiratory tract inflammation
  2. Renal impairment (severely reduced kidney function)
  3. Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
  4. Pain
  5. Cough
  6. Blood creatinine increased
  7. Anaemia (lack of blood)
  8. Back pain
  9. Dyspnoea (difficult or laboured respiration)
  10. Immunosuppressant drug level increased

Most common drug interactions by age *:

0-1:
  1. Arterial disorder
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
  4. Cellulitis (infection under the skin)
  5. Chest pain
  6. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  7. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  8. Fracture
  9. Infection
  10. Laceration (tearing of soft body tissue)
2-9:
  1. Behcet's syndrome (involves inflammation of the blood vessels)
10-19:
  1. Fluid retention (an abnormal accumulation of fluid in the blood)
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Staphylococcal sepsis (blood infection by an infection with staphylococcus bacteria)
  4. Adrenal insufficiency (condition in which the adrenal glands do not produce adequate amounts of steroids)
  5. Gastroenteritis (inflammation of stomach and intestine)
  6. Histiocytosis haematophagic
  7. Influenza
20-29:
  1. Pyrexia (fever)
  2. Viral infection
  3. Immunosuppressant drug level increased
  4. Aphthous stomatitis (mouth ulcer)
  5. Cough
  6. Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
  7. Eating disorder
  8. Pain
  9. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  10. Stomatitis (inflammation of mucous membrane of mouth)
30-39:
  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Constipation
  3. Upper respiratory tract inflammation
  4. Condition
  5. Nephrolithiasis (calculi in the kidneys)
  6. Blood creatinine increased
  7. Diarrhoea
  8. Hypertension (high blood pressure)
  9. Nasopharyngitis (inflammation of the nasopharynx)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)
40-49:
  1. Diarrhoea
  2. Oedema peripheral (superficial swelling)
  3. Anaemia (lack of blood)
  4. Condition
  5. Gastritis (inflammation of stomach)
  6. Hypertension (high blood pressure)
  7. Iron deficiency anaemia
  8. Nasopharyngitis (inflammation of the nasopharynx)
  9. Pruritus (severe itching of the skin)
  10. Adenomyosis (presence of ectopic glandular tissue found in muscle)
50-59:
  1. Dyspnoea (difficult or laboured respiration)
  2. Gait disturbance
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  5. Scar
  6. Skin ulcer
  7. Antinuclear antibody positive
  8. Arrhythmia (irregular heartbeat)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Blood creatinine increased
60+:
  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Renal impairment (severely reduced kidney function)
  3. Headache (pain in head)
  4. Diarrhoea
  5. Vomiting
  6. Dizziness
  7. Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
  8. Anaemia (lack of blood)
  9. Interstitial lung disease
  10. Cardiac failure

* Approximation only. Some reports may have incomplete information.


Do you take Alendronate sodium and Prograf?

You are not alone:




Related publications that referenced our studies

Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Alendronate sodium and drugs from A to Z
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Interactions between Prograf and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Alendronate sodium and Prograf
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Alendronate sodium and Prograf (26,855 reports studied)



FDA reports used in this study


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