Antabuse and Depakote drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Antabuse and Depakote. Common interactions include hepatic cirrhosis among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people who take Antabuse and Depakote have. It is created by eHealthMe based on reports of 36 people who take Antabuse and Depakote from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 28, 2022

36 people who take Antabuse and Depakote together, and have interactions are studied.


What is Antabuse?

Antabuse has active ingredients of disulfiram. It is often used in alcoholism. eHealthMe is studying from 1,155 Antabuse users for its effectiveness, alternative drugs and more.

What is Depakote?

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 52,727 Depakote users for its effectiveness, alternative drugs and more.

Number of Antabuse and Depakote reports submitted per year:

Antabuse and Depakote drug interactions.

Common Antabuse and Depakote drug interactions by gender *:

female:

  1. Hepatic cirrhosis
  2. Hyperglycaemia
  3. Hyperlipidaemia
  4. International normalised ratio increased
  5. Loss of consciousness
  6. Memory impairment
  7. Nausea
  8. Neuropathy peripheral
  9. Obesity
  10. Pancreatitis

male:

  1. Diabetes mellitus
  2. Abnormal dreams
  3. Cerebrovascular accident
  4. Chest pain
  5. Convulsions
  6. Deafness
  7. Delirium
  8. Depressed level of consciousness
  9. Depression
  10. Diabetes mellitus non-insulin-dependent

Common Antabuse and Depakote drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Vision blurred

20-29:

  1. Anxiety
  2. Diabetes mellitus
  3. Glucose tolerance impaired
  4. Loss of consciousness
  5. Nausea
  6. Supraventricular tachycardia
  7. Type 1 diabetes mellitus

30-39:

  1. Abnormal dreams
  2. Blood cholesterol increased
  3. Chest pain
  4. Constipation
  5. Convulsions
  6. Delirium
  7. Depressed level of consciousness
  8. Diabetes mellitus
  9. Diabetic coma
  10. Diabetic ketoacidosis

40-49:

  1. Panic attack
  2. Patella fracture
  3. Somnambulism
  4. Therapeutic response decreased
  5. Urinary retention
  6. Wrist fracture
  7. Mania
  8. Tooth loss
  9. Insomnia
  10. Drug ineffective

50-59:

  1. Hospitalisation
  2. Blood glucose increased
  3. Delusion
  4. Dyskinesia
  5. Tardive dyskinesia

60+:

n/a

Common conditions people have *:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 16 people, 44.44%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 44.44%
  3. Depression: 5 people, 13.89%
  4. Sleep Disorder: 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Antabuse and Depakote?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Antabuse and Depakote:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Antabuse interactions:

Browse all interactions between Antabuse and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Depakote interactions:

Browse all interactions between Depakote and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on disulfiram and divalproex sodium (the active ingredients of Antabuse and Depakote, respectively), and Antabuse and Depakote (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Antabuse and Depakote.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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