Apresoline and Alkeran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported only by a few people who take Apresoline and Alkeran together.

The phase IV clinical study analyzes what interactions people who take Apresoline and Alkeran have. It is created by eHealthMe based on reports of 4 people who take the same drugs from the FDA, and is updated regularly.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Oct, 01, 2022

4 people who take Apresoline and Alkeran together, and have interactions are studied.


What is Apresoline?

Apresoline has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,304 Apresoline users for its effectiveness, alternative drugs and more.

What is Alkeran?

Alkeran has active ingredients of melphalan. eHealthMe is studying from 5,429 Alkeran users for its effectiveness, alternative drugs and more.

Number of Apresoline and Alkeran reports submitted per year:

Apresoline and Alkeran drug interactions.

Common Apresoline and Alkeran drug interactions by gender *:

female:

  1. Asthenia
  2. Diarrhoea
  3. Epistaxis
  4. Mouth ulceration
  5. Mucosal inflammation
  6. Rash
  7. Somnolence

male:

  1. Haematuria
  2. Proteinuria
  3. Pericardial effusion
  4. Pleural effusion
  5. Pneumonia
  6. Pneumonia aspiration
  7. Posterior reversible encephalopathy syndrome
  8. Sepsis
  9. Stem cell transplant
  10. Renal failure acute

Common Apresoline and Alkeran drug interactions by age *:

0-1:

n/a

2-9:

  1. Haematuria
  2. Proteinuria
  3. Renal failure acute
  4. Stomatitis

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Enterococcus test positive
  2. Hypoxia
  3. Intestinal obstruction
  4. Pericardial effusion
  5. Pleural effusion
  6. Pneumonia
  7. Pneumonia aspiration
  8. Posterior reversible encephalopathy syndrome
  9. Sepsis
  10. Stem cell transplant

50-59:

n/a

60+:

  1. Asthenia
  2. Diarrhoea
  3. Epistaxis
  4. Mouth ulceration
  5. Mucosal inflammation
  6. Rash
  7. Somnolence

* Approximation only. Some reports may have incomplete information.

Do you take Apresoline and Alkeran?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Apresoline and Alkeran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Apresoline interactions:

Browse all interactions between Apresoline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Alkeran interactions:

Browse all interactions between Alkeran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydralazine hydrochloride and melphalan (the active ingredients of Apresoline and Alkeran, respectively), and Apresoline and Alkeran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Apresoline and Alkeran.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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