Benzonatate and Tretinoin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Benzonatate and Tretinoin. Common interactions include renal failure among females and hypothyroidism among males.
The phase IV clinical study analyzes what interactions people who take Benzonatate and Tretinoin have. It is created by eHealthMe based on reports of 47 people who take Benzonatate and Tretinoin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
47 people who take Benzonatate and Tretinoin together, and have interactions are studied.
What is Benzonatate?
Benzonatate has active ingredients of benzonatate. It is often used in cough. eHealthMe is studying from 14,176 Benzonatate users for its effectiveness, alternative drugs and more.
What is Tretinoin?
Tretinoin has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 5,058 Tretinoin users for its effectiveness, alternative drugs and more.
Number of Benzonatate and Tretinoin reports submitted per year:

Common Benzonatate and Tretinoin drug interactions by gender *:
female:
- Renal failure
- Sepsis
- Abdominal pain upper
- Abscess limb
- Alanine aminotransferase increased
- Alopecia
- Anxiety
- Arthralgia
- Arthropathy
- Aspartate aminotransferase increased
male:
- Hypothyroidism
- Diabetes mellitus non-insulin-dependent
- Asthenia
- Denervation atrophy
- Difficulty in walking
- Disease progression
- Fall
- Muscle atrophy
- Muscle cramp
- Muscle weakness
Common Benzonatate and Tretinoin drug interactions by age *:
0-1:
- Activities of daily living impaired
- Anhedonia
- Anxiety
- Balance disorder
- Extrapyramidal disorder
- Injury
- Muscle spasms
- Myoclonus
- Neuropathy peripheral
- Osteoarthritis
2-9:
n/a
10-19:
- Abdominal discomfort
- Deep vein thrombosis
- Dyspnoea
- Headache
- Hypoaesthesia
- Nausea
- Oedema peripheral
- Overdose
- Pain
- Pain in extremity
20-29:
n/a
30-39:
- Anxiety
- Deep vein thrombosis
- Emotional distress
- General physical health deterioration
- Injury
- Pain
- Pulmonary embolism
- Pulmonary hypertension
- Pulmonary infarction
- Right ventricular hypertrophy
40-49:
- Foot deformity
- Gastrointestinal disorder
- Glycosuria
- Haematoma
- Hypercholesterolaemia
- Hypertension
- Hypoaesthesia
- Hyporeflexia
- Insomnia
- Malaise
50-59:
- Sepsis
- Asthma
- Chronic kidney disease
- Groin abscess
- Abscess limb
- Anhedonia
- Anxiety
- Drug ineffective
- Emotional distress
- Erythema
60+:
- Chronic kidney disease
- Metastatic malignant melanoma
- Metastases to lymph nodes
- Nephrogenic anaemia
- Nephrolithiasis
- Pneumonia
- Respiratory failure
- Trigger finger
- Renal failure
- Alopecia
Common conditions people have *:
- Pain: 10 people, 21.28%
- Asthma: 9 people, 19.15%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 19.15%
- High Blood Cholesterol: 8 people, 17.02%
- Stress And Anxiety: 7 people, 14.89%
- High Blood Pressure: 7 people, 14.89%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 12.77%
- Depression: 6 people, 12.77%
- Hypokalemia (low potassium): 6 people, 12.77%
- Type 2 Diabetes: 6 people, 12.77%
* Approximation only. Some reports may have incomplete information.
Do you take Benzonatate and Tretinoin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Benzonatate (14,176 reports)
- Tretinoin (5,058 reports)
Common Benzonatate and Tretinoin interactions:
- Weakness: 4 reports
Browse all drug interactions of Benzonatate and Tretinoin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Benzonatate side effects:
- Chronic kidney disease: 1,516 reports
- Fatigue (feeling of tiredness): 1,124 reports
- Acute kidney failure: 1,115 reports
- Pneumonia: 1,041 reports
- Breathing difficulty: 928 reports
- Pain: 904 reports
- Diarrhea: 894 reports
- Cough: 840 reports
- Stress and anxiety: 705 reports
Browse all side effects of Benzonatate:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Tretinoin side effects:
- Drug ineffective: 365 reports
- Pain: 298 reports
- Rashes (redness): 219 reports
- Nausea and vomiting: 208 reports
- Headache (pain in head): 202 reports
- Stress and anxiety: 200 reports
- Diarrhea: 187 reports
- Fatigue (feeling of tiredness): 185 reports
Browse all side effects of Tretinoin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Benzonatate interactions:
- Benzonatate and Prednisone: 3,168 reports
- Benzonatate and Aspirin: 2,824 reports
- Benzonatate and Omeprazole: 2,523 reports
- Benzonatate and Gabapentin: 2,493 reports
- Benzonatate and Furosemide: 2,160 reports
- Benzonatate and Lisinopril: 2,063 reports
- Benzonatate and Albuterol: 1,973 reports
- Benzonatate and Tramadol: 1,918 reports
- Benzonatate and Pantoprazole: 1,860 reports
- Benzonatate and Amlodipine: 1,850 reports
Browse all interactions between Benzonatate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Tretinoin interactions:
- Tretinoin and Cytarabine: 503 reports
- Tretinoin and Vitamin d: 392 reports
- Tretinoin and Xyrem: 357 reports
- Tretinoin and Prednisone: 340 reports
- Tretinoin and Omeprazole: 335 reports
- Tretinoin and Ibuprofen: 303 reports
- Tretinoin and Arsenic trioxide: 302 reports
- Tretinoin and Doxycycline: 285 reports
- Tretinoin and Aspirin: 277 reports
- Tretinoin and Gabapentin: 270 reports
Browse all interactions between Tretinoin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on benzonatate and tretinoin (the active ingredients of Benzonatate and Tretinoin, respectively), and Benzonatate and Tretinoin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Benzonatate and Tretinoin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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