Bosentan and Levetiracetam drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among people who take Bosentan and Levetiracetam. Common interactions include nausea among females and pulmonary hypertension among males.

The phase IV clinical study analyzes what interactions people who take Bosentan and Levetiracetam have. It is created by eHealthMe based on reports of 17 people who take Bosentan and Levetiracetam from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Oct, 03, 2022

17 people who take Bosentan and Levetiracetam together, and have interactions are studied.

What is Bosentan?

Bosentan has active ingredients of bosentan. eHealthMe is studying from 8,260 Bosentan users for its effectiveness, alternative drugs and more.

What is Levetiracetam?

Levetiracetam has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 60,619 Levetiracetam users for its effectiveness, alternative drugs and more.

Number of Bosentan and Levetiracetam reports submitted per year:

Bosentan and Levetiracetam drug interactions.

Common Bosentan and Levetiracetam drug interactions by gender *:


  1. Nausea
  2. Vomiting
  3. Acute respiratory failure
  4. Atrial flutter
  5. Disease complication
  6. Hospitalisation
  7. Lung disorder
  8. Pneumonia klebsiella
  9. Pneumonia staphylococcal
  10. Trisomy 18


  1. Pulmonary hypertension
  2. Agitation
  3. Malnutrition
  4. Meningitis
  5. Muscle rigidity
  6. Myoclonic epilepsy
  7. Neuroleptic malignant syndrome
  8. Neurological symptom
  9. Respiratory tract infection
  10. Rhabdomyolysis

Common Bosentan and Levetiracetam drug interactions by age *:


  1. Agitation
  2. Autonomic nervous system imbalance
  3. Disseminated intravascular coagulation
  4. Hospitalisation
  5. Hyperthermia
  6. Hyperthermia malignant
  7. Hypotension
  8. Left ventricular failure
  9. Malnutrition
  10. Meningitis


  1. Acute respiratory failure
  2. Atrial flutter
  3. Disease complication
  4. Lung disorder
  5. Nausea
  6. Pneumonia klebsiella
  7. Pneumonia staphylococcal
  8. Trisomy 18
  9. Vomiting
  10. Hospitalisation


  1. Gastrointestinal disorder
  2. Hospitalisation




  1. Abdominal pain lower
  2. Depression
  3. Nausea
  4. Pelvic pain
  5. Suicidal ideation
  6. Vomiting


  1. Injection site erythema
  2. Injection site induration
  3. Injection site infection
  4. Injection site pain
  5. Injection site pruritus
  6. Injection site rash
  7. Nausea
  8. Pain in extremity
  9. Pruritus
  10. Breast cancer




  1. Cerebral haemorrhage
  2. Dyspnoea
  3. Fall
  4. Headache
  5. Neck pain
  6. Pneumonia

Common conditions people have *:

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 64.71%
  2. Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 11.76%
  3. Staphylococcal Infection (an infection with staphylococcus bacteria): 1 person, 5.88%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  5. Myositis (inflammation of the muscles): 1 person, 5.88%
  6. Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 1 person, 5.88%
  7. Iron Deficiency Anaemia: 1 person, 5.88%
  8. Insomnia (sleeplessness): 1 person, 5.88%
  9. Infantile Spasms: 1 person, 5.88%
  10. Asthma: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Bosentan and Levetiracetam?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Bosentan and Levetiracetam:

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Common Bosentan interactions:

Browse all interactions between Bosentan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Levetiracetam interactions:

Browse all interactions between Levetiracetam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on bosentan and levetiracetam (the active ingredients of Bosentan and Levetiracetam, respectively), and Bosentan and Levetiracetam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Bosentan and Levetiracetam.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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