Brintellix and Paroxetine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Brintellix and Paroxetine. Common interactions include drug ineffective among females and tremor among males.
The phase IV clinical study analyzes what interactions people who take Brintellix and Paroxetine have. It is created by eHealthMe based on reports of 52 people who take Brintellix and Paroxetine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
52 people who take Brintellix and Paroxetine together, and have interactions are studied.
What is Brintellix?
Brintellix has active ingredients of vortioxetine hydrobromide. It is often used in depression. eHealthMe is studying from 6,025 Brintellix users for its effectiveness, alternative drugs and more.
What is Paroxetine?
Paroxetine has active ingredients of paroxetine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 58,180 Paroxetine users for its effectiveness, alternative drugs and more.
Number of Brintellix and Paroxetine reports submitted per year:

Common Brintellix and Paroxetine drug interactions by gender *:
female:
- Drug ineffective
- Crying
- Decreased appetite
- Diarrhoea
- Feeling drunk
- Head discomfort
- Suicidal ideation
- Fall
- Gait disturbance
- Psychomotor retardation
male:
- Tremor
- Antipsychotic drug level increased
- Decreased appetite
- Drug ineffective
- Drug withdrawal syndrome
- Irritability
- Loss of libido
- Acquired phimosis
- Angioedema
- Blood pressure increased
Common Brintellix and Paroxetine drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Urinary retention
- Intentional self-injury
- Sluggishness
- Sexual dysfunction
30-39:
- Hypertonia
- Libido decreased
- Salivary hypersecretion
- Tremor
40-49:
- Acquired phimosis
- Bradycardia
- Hypertension
- Priapism
50-59:
- Fall
- Gait disturbance
- Psychomotor retardation
- Hepatocellular injury
- Headache
- Angioedema
- Chronic kidney disease
- Hypersensitivity
- Hypoaesthesia
- Hypomania
60+:
- Tremor
- Crying
- Epistaxis
- Platelet count decreased
- Deep brain stimulation
- Hallucination
- Bradycardia
- Mydriasis
- Aortic dilatation
- Aortic valve incompetence
Common conditions people have *:
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 19.23%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 10 people, 19.23%
- Psychotic Disorder: 6 people, 11.54%
* Approximation only. Some reports may have incomplete information.
Do you take Brintellix and Paroxetine?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Coskun M, Adak I, Akaltun I, "Bilateral gynecomastia in a preadolescent boy while under treatment with methylphenidate and paroxetine", Journal of clinical psychopharmacology, 2014 Aug .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Brintellix (6,025 reports)
- Paroxetine (58,180 reports)
Browse all drug interactions of Brintellix and Paroxetine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Brintellix side effects:
- Suicidal ideation: 389 reports
- Indigestion: 333 reports
- Drug ineffective: 295 reports
- Stress and anxiety: 286 reports
- Itching: 281 reports
- Headache (pain in head): 275 reports
- Dizziness: 261 reports
- Rashes (redness): 221 reports
- Insomnia (sleeplessness): 207 reports
Browse all side effects of Brintellix:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Paroxetine side effects:
- Stress and anxiety: 4,007 reports
- Fatigue (feeling of tiredness): 3,970 reports
- Dizziness: 3,506 reports
- Drug ineffective: 3,397 reports
- Depression: 3,150 reports
- Headache (pain in head): 3,042 reports
- Diarrhea: 2,844 reports
- Suicidal ideation: 2,774 reports
Browse all side effects of Paroxetine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Brintellix interactions:
- Brintellix and Xyrem: 378 reports
- Brintellix and Lorazepam: 281 reports
- Brintellix and Xanax: 247 reports
- Brintellix and Alprazolam: 223 reports
- Brintellix and Gabapentin: 220 reports
- Brintellix and Wellbutrin: 218 reports
- Brintellix and Adderall: 217 reports
- Brintellix and Abilify: 216 reports
- Brintellix and Clonazepam: 214 reports
- Brintellix and Omeprazole: 204 reports
Browse all interactions between Brintellix and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Paroxetine interactions:
- Paroxetine and Omeprazole: 4,661 reports
- Paroxetine and Alprazolam: 4,198 reports
- Paroxetine and Aspirin: 3,845 reports
- Paroxetine and Lorazepam: 3,570 reports
- Paroxetine and Gabapentin: 3,554 reports
- Paroxetine and Prednisone: 3,343 reports
- Paroxetine and Metformin: 3,337 reports
- Paroxetine and Furosemide: 3,325 reports
- Paroxetine and Clonazepam: 3,187 reports
- Paroxetine and Lisinopril: 3,097 reports
Browse all interactions between Paroxetine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on vortioxetine hydrobromide and paroxetine hydrochloride (the active ingredients of Brintellix and Paroxetine, respectively), and Brintellix and Paroxetine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Brintellix and Paroxetine.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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