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Cardura and Rapamune drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cardura and Rapamune. Common interactions include diverticulum among females and kidney transplant rejection among males.

The phase IV clinical study analyzes what interactions people who take Cardura and Rapamune have. It is created by eHealthMe based on reports of 74 people who take Cardura and Rapamune from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Dec, 02, 2022

74 people who take Cardura and Rapamune together, and have interactions are studied.

What is Cardura?

Cardura has active ingredients of doxazosin mesylate. It is often used in high blood pressure. eHealthMe is studying from 19,907 Cardura users for its effectiveness, alternative drugs and more.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,319 Rapamune users for its effectiveness, alternative drugs and more.

Number of Cardura and Rapamune reports submitted per year:

Cardura and Rapamune drug interactions.

Common Cardura and Rapamune drug interactions by gender *:

female:

  1. Diverticulum
  2. Hydronephrosis
  3. Hypophagia
  4. Lactic acidosis
  5. Metabolic acidosis
  6. Blood creatine increased
  7. Blood lactate dehydrogenase increased
  8. Blood magnesium increased
  9. Blood triglycerides increased
  10. Disseminated intravascular coagulation

male:

  1. Kidney transplant rejection
  2. Renal impairment
  3. Tremor
  4. Vomiting
  5. Activated partial thromboplastin time prolonged
  6. Blood creatinine increased
  7. Blood glucose increased
  8. Blood lactate dehydrogenase increased
  9. Bone marrow depression
  10. Failure to thrive

Common Cardura and Rapamune drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Diabetes mellitus
  2. Dissociative disorder
  3. Encephalitis

20-29:

  1. Disseminated intravascular coagulation
  2. Loin pain
  3. Nephritis
  4. Pyelonephritis
  5. Pyrexia
  6. White blood cells urine positive

30-39:

  1. Asthma
  2. Blood lactate dehydrogenase increased
  3. Blood magnesium increased
  4. Blood triglycerides increased
  5. Central nervous system lesion
  6. Cor pulmonale chronic
  7. Deep vein thrombosis
  8. Depression
  9. Ejection fraction decreased
  10. Extremity contracture

40-49:

  1. Renal impairment
  2. Drug hypersensitivity
  3. Nasal congestion
  4. Diarrhoea
  5. Haemoglobin decreased
  6. Osteonecrosis
  7. Blood pressure systolic increased
  8. Haematocrit decreased
  9. Kidney transplant rejection
  10. Nausea

50-59:

  1. Blood uric acid increased
  2. Conjunctival oedema
  3. Cytomegalovirus infection
  4. Diabetes mellitus inadequate control
  5. Dyspnoea
  6. Eye irritation
  7. Eye oedema
  8. Eye pain
  9. Eyelid oedema
  10. Gout

60+:

  1. Kidney transplant rejection
  2. Abdominal pain
  3. Balance disorder
  4. Blood bilirubin increased
  5. Epistaxis
  6. Fluid overload
  7. Gastroenteritis
  8. General physical health deterioration
  9. Haemoglobin decreased
  10. Hepatic failure

Common conditions people have *:

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Cardura and Rapamune?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Cardura and Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Cardura side effects:

Browse all side effects of Cardura:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Rapamune side effects:

Browse all side effects of Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Cardura interactions:

Browse all interactions between Cardura and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Rapamune interactions:

Browse all interactions between Rapamune and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on doxazosin mesylate and sirolimus (the active ingredients of Cardura and Rapamune, respectively), and Cardura and Rapamune (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Cardura and Rapamune.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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