Carvedilol and Evening primrose oil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Carvedilol and Evening primrose oil. Common interactions include bowel movement irregularity among females and blood cholesterol increased among males.
The phase IV clinical study analyzes what interactions people who take Carvedilol and Evening primrose oil have. It is created by eHealthMe based on reports of 7 people who take Carvedilol and Evening primrose oil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
7 people who take Carvedilol and Evening primrose oil together, and have interactions are studied.
What is Carvedilol?
Carvedilol has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 97,371 Carvedilol users for its effectiveness, alternative drugs and more.
What is Evening primrose oil?
Evening primrose oil has active ingredients of evening primrose oil. It is often used in premenstrual syndrome. eHealthMe is studying from 1,230 Evening primrose oil users for its effectiveness, alternative drugs and more.
Number of Carvedilol and Evening primrose oil reports submitted per year:

Common Carvedilol and Evening Primrose Oil drug interactions by gender *:
female:
- Bowel movement irregularity
- Constipation
- Diarrhoea
- Gastrointestinal tract irritation
- Haemorrhage
- Muscle spasms
male:
- Blood cholesterol increased
- Blood glucose increased
- Oral mucosal blistering
- Sleep disorder
- Somnolence
- White blood cell count decreased
- Blood triglycerides increased
- Diarrhoea
- Dizziness
- Drug ineffective
Common Carvedilol and Evening Primrose Oil drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Drug ineffective
- White blood cell count decreased
60+:
- Diarrhoea
- Blood cholesterol increased
- Haemorrhage
- Low density lipoprotein increased
- Muscle spasms
- Nausea
- Oral mucosal blistering
- Sleep disorder
- Somnolence
- Blood glucose increased
* Approximation only. Some reports may have incomplete information.
Do you take Carvedilol and Evening primrose oil?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Min IS, Lee JY, Jung TS, Kang NK, Park BB, Kim BK, "Development of a Complete Atrioventricular Block Associated with Intake of Evening Primrose Oil", The Korean Journal of Medicine, 2016 May .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Carvedilol (97,371 reports)
- Evening primrose oil (1,230 reports)
Browse all drug interactions of Carvedilol and Evening primrose oil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Carvedilol side effects:
- Fatigue (feeling of tiredness): 6,610 reports
- Breathing difficulty: 6,175 reports
- Hypotension (abnormally low blood pressure): 5,548 reports
- Diarrhea: 4,974 reports
- Dizziness: 4,960 reports
- Weakness: 4,730 reports
Browse all side effects of Carvedilol:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Evening primrose oil side effects:
- Fatigue (feeling of tiredness): 138 reports
- Headache (pain in head): 118 reports
Browse all side effects of Evening primrose oil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Carvedilol interactions:
- Carvedilol and Aspirin: 24,958 reports
- Carvedilol and Furosemide: 23,097 reports
- Carvedilol and Lisinopril: 16,653 reports
- Carvedilol and Amlodipine: 14,791 reports
- Carvedilol and Metformin: 11,555 reports
- Carvedilol and Omeprazole: 11,179 reports
- Carvedilol and Spironolactone: 10,246 reports
- Carvedilol and Simvastatin: 9,862 reports
- Carvedilol and Losartan: 9,347 reports
- Carvedilol and Gabapentin: 8,580 reports
Browse all interactions between Carvedilol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Evening primrose oil interactions:
- Evening primrose oil and Vitamin d: 232 reports
- Evening primrose oil and Fish oil: 194 reports
- Evening primrose oil and Aspirin: 166 reports
- Evening primrose oil and Calcium: 150 reports
- Evening primrose oil and Magnesium: 146 reports
- Evening primrose oil and Vitamin c: 144 reports
- Evening primrose oil and Vitamin b12: 139 reports
- Evening primrose oil and Omeprazole: 135 reports
- Evening primrose oil and Vitamin d3: 103 reports
Browse all interactions between Evening primrose oil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on carvedilol and evening primrose oil (the active ingredients of Carvedilol and Evening primrose oil, respectively), and Carvedilol and Evening primrose oil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Carvedilol and Evening primrose oil.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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