Climara and Primidone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Climara and Primidone. Common interactions include nephrolithiasis among females.

The phase IV clinical study analyzes what interactions people who take Climara and Primidone have. It is created by eHealthMe based on reports of 19 people who take Climara and Primidone from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Dec, 07, 2022

19 people who take Climara and Primidone together, and have interactions are studied.


What is Climara?

Climara has active ingredients of estradiol. It is often used in menopause. eHealthMe is studying from 6,489 Climara users for its effectiveness, alternative drugs and more.

What is Primidone?

Primidone has active ingredients of primidone. It is often used in essential tremor. eHealthMe is studying from 9,103 Primidone users for its effectiveness, alternative drugs and more.

Number of Climara and Primidone reports submitted per year:

Climara and Primidone drug interactions.

Common Climara and Primidone drug interactions by gender *:

female:

  1. Nephrolithiasis
  2. Abdominal pain upper
  3. Osteoarthritis
  4. Sleep apnoea syndrome
  5. Weight decreased
  6. Bladder prolapse
  7. Sinusitis
  8. Acute sinusitis
  9. Blood pressure decreased
  10. Brain neoplasm

male:

n/a

Common Climara and Primidone drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Abdominal pain upper
  2. Back injury
  3. Weight increased
  4. Constipation
  5. Fall
  6. Foot deformity
  7. Hepatic enzyme increased
  8. Insomnia
  9. Renal failure acute
  10. Renal failure chronic

Common conditions people have *:

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 89.47%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 12 people, 63.16%
  3. Drowsiness: 7 people, 36.84%
  4. Back Injury: 5 people, 26.32%
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 21.05%
  6. Dry Skin: 4 people, 21.05%
  7. Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 21.05%
  8. Fungal Nail Infection: 4 people, 21.05%
  9. Gastrointestinal Motility Disorder (abnormal intestinal contractions): 4 people, 21.05%
  10. Heart Rate Irregular: 4 people, 21.05%

* Approximation only. Some reports may have incomplete information.

Do you take Climara and Primidone?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Climara and Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Climara side effects:

Browse all side effects of Climara:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Primidone side effects:

Browse all side effects of Primidone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Climara interactions:

Browse all interactions between Climara and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Primidone interactions:

Browse all interactions between Primidone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on estradiol and primidone (the active ingredients of Climara and Primidone, respectively), and Climara and Primidone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Climara and Primidone.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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