Clopidogrel and Kombiglyze xr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clopidogrel and Kombiglyze xr. Common interactions include cardiac failure congestive among females and cardiac failure congestive among males.
The phase IV clinical study analyzes what interactions people who take Clopidogrel and Kombiglyze xr have. It is created by eHealthMe based on reports of 43 people who take Clopidogrel and Kombiglyze xr from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
43 people who take Clopidogrel and Kombiglyze xr together, and have interactions are studied.
What is Clopidogrel?
Clopidogrel has active ingredients of clopidogrel. It is often used in blood clots. eHealthMe is studying from 79,618 Clopidogrel users for its effectiveness, alternative drugs and more.
What is Kombiglyze xr?
Kombiglyze xr has active ingredients of metformin hydrochloride; saxagliptin. It is often used in diabetes. eHealthMe is studying from 2,613 Kombiglyze xr users for its effectiveness, alternative drugs and more.
Number of Clopidogrel and Kombiglyze xr reports submitted per year:

Common Clopidogrel and Kombiglyze Xr drug interactions by gender *:
female:
- Cardiac failure congestive
- Cardiac failure
- Chronic kidney disease
- Cardiovascular disorder
- Renal failure
- Renal injury
- Blood glucose increased
- Bone disorder
- Dyskinesia
- Gastritis
male:
- Cardiac failure congestive
- Cardiac failure
- Coronary artery occlusion
- Coronary artery stenosis
- Drug ineffective
- Dysuria
- Fall
- Hypertension
- Incisional hernia
- Left ventricular failure
Common Clopidogrel and Kombiglyze Xr drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Cardiac failure
- Cardiac failure congestive
- Cardiomyopathy
- Cardiovascular disorder
- Coronary artery disease
50-59:
- Cardiac failure congestive
- Cardiac failure
- Coronary artery disease
- Cardiovascular disorder
- Coronary artery stenosis
- Chronic left ventricular failure
- Diastolic dysfunction
- Ischaemic cardiomyopathy
- Acute left ventricular failure
- Left ventricular failure
60+:
- Cardiac failure congestive
- Cardiac failure
- Blood glucose increased
- Weight decreased
- Renal injury
- Bone disorder
- Dyskinesia
- Gastritis
- Hyperkeratosis
- Influenza
Common conditions people have *:
- Type 2 Diabetes: 21 people, 48.84%
- High Blood Pressure: 6 people, 13.95%
- High Blood Cholesterol: 6 people, 13.95%
- Pain: 5 people, 11.63%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.30%
- Cardiac Disorder: 3 people, 6.98%
* Approximation only. Some reports may have incomplete information.
Do you take Clopidogrel and Kombiglyze xr?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Lai SW, Lin CL, Liao KF, "Actively using clopidogrel correlates with an increased risk of acute pancreatitis in Taiwan", International journal of cardiology, 2015 Mar .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Clopidogrel (79,618 reports)
- Kombiglyze xr (2,613 reports)
Browse all drug interactions of Clopidogrel and Kombiglyze xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Clopidogrel side effects:
- Breathing difficulty: 4,485 reports
- Fatigue (feeling of tiredness): 4,088 reports
- Dizziness: 3,829 reports
- Weakness: 3,360 reports
- Diarrhea: 3,158 reports
Browse all side effects of Clopidogrel:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Kombiglyze xr side effects:
- Heart disease: 248 reports
- Diarrhea: 195 reports
- Death: 137 reports
- Drug ineffective: 119 reports
- Dizziness: 106 reports
- High blood pressure: 102 reports
Browse all side effects of Kombiglyze xr:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Clopidogrel interactions:
- Clopidogrel and Aspirin: 21,878 reports
- Clopidogrel and Furosemide: 11,370 reports
- Clopidogrel and Amlodipine: 10,425 reports
- Clopidogrel and Simvastatin: 9,920 reports
- Clopidogrel and Pantoprazole: 9,346 reports
- Clopidogrel and Metformin: 8,719 reports
- Clopidogrel and Acetylsalicylic acid: 8,653 reports
- Clopidogrel and Ramipril: 7,815 reports
- Clopidogrel and Omeprazole: 7,263 reports
- Clopidogrel and Lisinopril: 6,970 reports
Browse all interactions between Clopidogrel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Kombiglyze xr interactions:
- Kombiglyze xr and Onglyza: 580 reports
- Kombiglyze xr and Metformin: 351 reports
- Kombiglyze xr and Lisinopril: 296 reports
- Kombiglyze xr and Aspirin: 281 reports
- Kombiglyze xr and Amlodipine: 178 reports
- Kombiglyze xr and Simvastatin: 150 reports
- Kombiglyze xr and Losartan: 147 reports
- Kombiglyze xr and Glimepiride: 137 reports
- Kombiglyze xr and Crestor: 136 reports
- Kombiglyze xr and Furosemide: 132 reports
Browse all interactions between Kombiglyze xr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on clopidogrel and metformin hydrochloride; saxagliptin (the active ingredients of Clopidogrel and Kombiglyze xr, respectively), and Clopidogrel and Kombiglyze xr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Clopidogrel and Kombiglyze xr.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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