Cordarone and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cordarone and Centrum. Common interactions include glaucoma among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people who take Cordarone and Centrum have. It is created by eHealthMe based on reports of 37 people who take Cordarone and Centrum from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

37 people who take Cordarone and Centrum together, and have interactions are studied.

What is Cordarone?

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 22,007 Cordarone users for its effectiveness, alternative drugs and more.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 33,488 Centrum users for its effectiveness, alternative drugs and more.

Number of Cordarone and Centrum reports submitted per year:

Common Cordarone and Centrum drug interactions by gender *:

female:

Glaucoma
Haemorrhagic anaemia
Headache
Heart rate increased
Hypotension
Injury
Laryngitis
Left ventricular dysfunction
Mobility decreased
Multiple injuries

male:

Gastrointestinal haemorrhage
Haematuria
Apnoea
Death
Dizziness
Drug ineffective
Dyspnoea
Epistaxis
Haemorrhage intracranial
Hypotension

Common Cordarone and Centrum drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dysphagia
Peripheral swelling
Respiratory arrest
Skin papilloma
Acne
Arteriosclerosis
Arthralgia
Cardiac arrest
Catheter site oedema
Catheter site pain

50-59:

Glycosylated haemoglobin increased

60+:

Asthenia
Nausea
Dyspnoea
Gastrointestinal haemorrhage
Haematuria
Haemoptysis
Hypothyroidism
Hypoxia
Leukocytosis
Malnutrition

Common conditions people have *:

Insomnia (sleeplessness): 8 people, 21.62%
High Blood Pressure: 8 people, 21.62%
Pain: 7 people, 18.92%
Diarrhea: 5 people, 13.51%
Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 5 people, 13.51%
Nausea (feeling of having an urge to vomit): 4 people, 10.81%
Constipation: 3 people, 8.11%
High Blood Cholesterol: 3 people, 8.11%
Stress And Anxiety: 3 people, 8.11%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 5.41%

* Approximation only. Some reports may have incomplete information.

Do you take Cordarone and Centrum?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Tesic D, Kostic M, Paunovic D, Jankovic SM, "Analysis of the cost–effectiveness of dronedarone versus amiodarone, propafenone, and sotalol in patients with atrial fibrillation: results for Serbia", Kardiologia Polska (Polish Heart Journal), 2016 Jan .
Kim DJ, Lee SC, Park GS, Kim GJ, Hwang WT, Lee CS, Lee MH, Hahn DH, Koh HC, "Amiodarone Induced Multiorgan Toxicity in a Patient of Hypertrophic Cardiomyopathy With Atrial Fibrillation", Journal of the Korean Geriatrics Society, 2013 Dec .