Cyclosporine and Mesalamine drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among people who take Cyclosporine and Mesalamine. Common interactions include muscular weakness among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people who take Cyclosporine and Mesalamine have. It is created by eHealthMe based on reports of 80 people who take Cyclosporine and Mesalamine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 28, 2022

80 people who take Cyclosporine and Mesalamine together, and have interactions are studied.

What is Cyclosporine?

Cyclosporine has active ingredients of cyclosporine. It is often used in psoriasis. eHealthMe is studying from 46,172 Cyclosporine users for its effectiveness, alternative drugs and more.

What is Mesalamine?

Mesalamine has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 15,051 Mesalamine users for its effectiveness, alternative drugs and more.

Number of Cyclosporine and Mesalamine reports submitted per year:

Cyclosporine and Mesalamine drug interactions.

Common Cyclosporine and Mesalamine drug interactions by gender *:


  1. Muscular weakness
  2. Neurilemmoma
  3. Neuropathy peripheral
  4. Pain
  5. Spasmodic dysphonia
  6. Speech disorder
  7. Cough
  8. Pneumonia
  9. Weight decreased
  10. Autoimmune thyroiditis


  1. Diarrhoea
  2. Pyrexia
  3. Adverse event
  4. Blindness
  5. Drug ineffective
  6. Feeling cold
  7. Histiocytosis haematophagic
  8. Psoriatic arthropathy
  9. Syncope
  10. Tremor

Common Cyclosporine and Mesalamine drug interactions by age *:




  1. Fungal skin infection
  2. Histiocytosis haematophagic
  3. Septic shock
  4. Viral infection


  1. Syncope
  2. Gingival hypertrophy
  3. Nephropathy toxic
  4. Pyrexia
  5. Abdominal symptom
  6. Acinetobacter test positive
  7. Blood creatinine increased
  8. C-reactive protein increased
  9. Convulsion
  10. Cutaneous vasculitis


  1. Abdominal pain
  2. Gastrointestinal haemorrhage
  3. Headache
  4. Ileal ulcer
  5. Liver disorder
  6. Neurilemmoma
  7. Pain
  8. Diarrhoea haemorrhagic
  9. Face oedema
  10. Hypoalbuminaemia


  1. Abdominal pain
  2. Abortion spontaneous
  3. Constipation
  4. Drug exposure during pregnancy
  5. Headache
  6. Hypersensitivity
  7. Hypoaesthesia
  8. Insomnia
  9. Irritability
  10. Mood swings


  1. Haematochezia
  2. Drug ineffective
  3. Abdominal pain
  4. Anorexia
  5. Drug hypersensitivity
  6. Gait disturbance
  7. Osteonecrosis
  8. Rheumatoid arthritis
  9. Bleeding varicose vein
  10. Complications of transplanted liver


  1. Amnesia
  2. Ataxia
  3. Balance disorder
  4. Cerebellar atrophy
  5. Cerebral ischaemia
  6. Dysarthria
  7. Gait disturbance
  8. Muscular weakness
  9. Neuropathy peripheral
  10. Spasmodic dysphonia


  1. Cough
  2. Weight decreased
  3. Pneumonia
  4. White blood cell count decreased
  5. Abdominal pain
  6. Adverse event
  7. Blood albumin decreased
  8. Brain natriuretic peptide increased
  9. Breath sounds
  10. Coronary artery disease

Common conditions people have *:

  1. Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 23 people, 28.75%
  2. Inflammatory Bowel Disease: 8 people, 10.00%
  3. Pain: 5 people, 6.25%
  4. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 6.25%
  5. High Blood Pressure: 5 people, 6.25%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 5.00%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.00%
  8. Dry Eyes (lack of adequate tears): 4 people, 5.00%
  9. Colitis (inflammation of colon): 4 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Cyclosporine and Mesalamine?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Cyclosporine and Mesalamine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Cyclosporine interactions:

Browse all interactions between Cyclosporine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Mesalamine interactions:

Browse all interactions between Mesalamine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and mesalamine (the active ingredients of Cyclosporine and Mesalamine, respectively), and Cyclosporine and Mesalamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Cyclosporine and Mesalamine.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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