Cylert and Prozac drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 95 people who take Cylert and Prozac. Common interactions include hypoaesthesia among females, and headache among males.

The phase IV clinical study analyzes what interactions people who take Cylert and Prozac have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 700+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 25, 2023

95 people who take Cylert and Prozac together, and have interactions are studied.

What is Cylert?

Cylert has active ingredients of pemoline. Currently, eHealthMe is studying from 785 Cylert users.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is used in depression. Currently, eHealthMe is studying from 81,208 Prozac users.

Number of Cylert and Prozac reports submitted per year:

Cylert and Prozac drug interactions.

Common Cylert and Prozac drug interactions by gender *:


  1. Hypoaesthesia
  2. Influenza like illness
  3. Injection site inflammation
  4. Asthma
  5. Cerebral artery thrombosis
  6. Confusion
  7. Diarrhoea
  8. Dyspepsia
  9. Gastro-oesophageal reflux disease
  10. Hemiplegia


  1. Headache
  2. Aggression
  3. Agitation
  4. Anger
  5. Bipolar disorder
  6. Brain injury
  7. Disturbance in social behaviour
  8. Drug administration error
  9. Drug dependence
  10. Emotional disorder

Common Cylert and Prozac drug interactions by age *:




  1. Drug ineffective
  2. Epistaxis


  1. Tongue neoplasm malignant stage unspecified
  2. Squamous cell carcinoma
  3. Oral soft tissue disorder


  1. Headache
  2. Drug dependence
  3. Drug withdrawal syndrome
  4. Neck pain
  5. Pain in limb
  6. Rebound effect
  7. Sleep disorder
  8. Stress symptoms
  9. Dysthymic disorder
  10. Insomnia


  1. Cerebral artery thrombosis
  2. Confusion
  3. Hemiplegia
  4. Amnesia
  5. Arthritis
  6. Ataxia
  7. Cardiac disorder
  8. Difficulty in walking
  9. Granuloma
  10. Hallucination, auditory


  1. Multiple sclerosis
  2. Pain
  3. White blood cell count decreased
  4. Alanine aminotransferase increased
  5. Chest pain
  6. Dysarthria
  7. Hemiparesis
  8. Hypoaesthesia
  9. Injection site inflammation
  10. Injection site pain


  1. Valvular heart disease
  2. Word salad
  3. Dyspnoea
  4. Multiple sclerosis
  5. Urinary incontinence
  6. Chest pain
  7. Arthritis
  8. Asthenia
  9. Asthma
  10. Diarrhoea


  1. Headache
  2. Hypertension
  3. Dyspepsia
  4. Hearing impaired
  5. Hot flushes
  6. Hyponatraemia
  7. Hypothyroidism
  8. Inappropriate adh secretion
  9. Injection site erythema
  10. Injection site inflammation

* Approximation only. Some reports may have incomplete information.

Do you take Cylert and Prozac?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Common Prozac side effects:

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Cylert interactions:

Browse all interactions between Cylert and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Prozac interactions:

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pemoline and fluoxetine hydrochloride (the active ingredients of Cylert and Prozac, respectively), and Cylert and Prozac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Cylert and Prozac.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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