Defitelio and Foscavir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Defitelio and Foscavir. Common interactions include cholestasis among females and acute respiratory distress syndrome among males.
The phase IV clinical study analyzes what interactions people who take Defitelio and Foscavir have. It is created by eHealthMe based on reports of 25 people who take Defitelio and Foscavir from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
25 people who take Defitelio and Foscavir together, and have interactions are studied.
What is Defitelio?
Defitelio has active ingredients of defibrotide sodium. eHealthMe is studying from 3,105 Defitelio users for its effectiveness, alternative drugs and more.
What is Foscavir?
Foscavir has active ingredients of foscarnet sodium. eHealthMe is studying from 1,548 Foscavir users for its effectiveness, alternative drugs and more.
Number of Defitelio and Foscavir reports submitted per year:

Common Defitelio and Foscavir drug interactions by gender *:
female:
- Cholestasis
- Drug ineffective
- Hepatitis a
- Intermenstrual bleeding
- Pulmonary toxicity
- Venoocclusive disease
- Acute respiratory distress syndrome
- Colitis
- Death
- Disease progression
male:
- Acute respiratory distress syndrome
- Graft versus host disease
- Platelet count decreased
- Renal impairment
- Subarachnoid haemorrhage
- Bone marrow failure
- Staphylococcal sepsis
- Pneumonia
- Cerebral haemorrhage
Common Defitelio and Foscavir drug interactions by age *:
0-1:
n/a
2-9:
- Acute respiratory distress syndrome
- Colitis
- Gastritis
- Melaena
- Overdose
- Pericardial effusion
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Venoocclusive disease
- Pneumonia
- Bone marrow failure
- Death
- Disease progression
- Graft versus host disease
- Renal impairment
- Acute respiratory distress syndrome
- Cerebral haemorrhage
- Cholestasis
60+:
- Platelet count decreased
- Subarachnoid haemorrhage
- Staphylococcal sepsis
Common conditions people have *:
- Venoocclusive Liver Disease (small veins in the liver are obstructed): 18 people, 72.00%
- Fever: 9 people, 36.00%
- Sepsis (a severe blood infection that can lead to organ failure and death): 7 people, 28.00%
- Pulmonary Veno-Occlusive Disease (obstructive disease of the pulmonary veins): 7 people, 28.00%
- Disease Recurrence: 7 people, 28.00%
- Diarrhea: 7 people, 28.00%
- Venoocclusive Disease (small veins in the liver are obstructed): 5 people, 20.00%
- Cytomegalovirus Infection: 5 people, 20.00%
- Staphylococcal Infection (an infection with staphylococcus bacteria): 2 people, 8.00%
- Pneumonia: 2 people, 8.00%
* Approximation only. Some reports may have incomplete information.
Do you take Defitelio and Foscavir?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Defitelio and Foscavir:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Defitelio side effects:
- Death: 708 reports
- Acute kidney failure: 171 reports
- Septic shock (shock due to blood infection): 124 reports
Browse all side effects of Defitelio:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Foscavir side effects:
- Thrombocytopenia (decrease of platelets in blood): 112 reports
- Fever: 110 reports
Browse all side effects of Foscavir:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Defitelio interactions:
- Defitelio and Cyclophosphamide: 188 reports
- Defitelio and Fludara: 178 reports
- Defitelio and Heparin: 149 reports
- Defitelio and Furosemide: 105 reports
Browse all interactions between Defitelio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Foscavir interactions:
- Foscavir and Bactrim: 171 reports
- Foscavir and Prograf: 167 reports
- Foscavir and Solu-medrol: 140 reports
- Foscavir and Fludara: 128 reports
- Foscavir and Methotrexate: 120 reports
- Foscavir and Prednisolone: 118 reports
- Foscavir and Fluconazole: 117 reports
- Foscavir and Vfend: 111 reports
- Foscavir and Tacrolimus: 110 reports
Browse all interactions between Foscavir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on defibrotide sodium and foscarnet sodium (the active ingredients of Defitelio and Foscavir, respectively), and Defitelio and Foscavir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Defitelio and Foscavir.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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