Diovan and Avandia drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Diovan and Avandia together. This study is created by eHealthMe based on reports of 1,931 people who take Diovan and Avandia from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on valsartan and rosiglitazone maleate (the active ingredients of Diovan and Avandia, respectively), and Diovan and Avandia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Diovan?

Diovan has active ingredients of valsartan. It is often used in high blood pressure. (latest outcomes from Diovan 72,779 users)

What is Avandia?

Avandia has active ingredients of rosiglitazone maleate. It is often used in diabetes. (latest outcomes from Avandia 141,364 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Feb, 22, 2019

1,931 people who take Diovan, Avandia are studied.


Number of reports submitted per year:

Diovan and Avandia drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Pain
  3. Anxiety
  4. Cardiac failure congestive
  5. Emotional distress
  6. Fear
  7. Renal failure (kidney dysfunction)
  8. Renal impairment (severely reduced kidney function)
  9. Renal injury (kidney injury)
  10. Stress
1 - 6 months:
  1. Cardiac failure congestive
  2. Oedema peripheral (superficial swelling)
  3. Weight increased
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  7. Fatigue (feeling of tiredness)
  8. Blood glucose increased
  9. Drug ineffective
  10. Dyspnoea (difficult or laboured respiration)
6 - 12 months:
  1. Acute myocardial infarction (acute heart attack)
  2. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  3. Insomnia (sleeplessness)
  4. Cardiac valve disease (heart valve disease)
  5. Emotional distress
  6. Muscle strain (an injury to a muscle in which the muscle fibres tear)
  7. Nervousness
  8. Respiratory failure (inadequate gas exchange by the respiratory system)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Facet joint syndrome (problem with movement of the facet joints of the spine)
1 - 2 years:
  1. Cardiac failure congestive
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Dyspnoea (difficult or laboured respiration)
  6. Cardiac disorder
  7. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  8. Cardiovascular disorder (heart diseases)
  9. Injury
  10. Oedema peripheral (superficial swelling)
2 - 5 years:
  1. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  2. Cardiac failure congestive
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Heart injury
  6. Mitral valve incompetence (inefficient heart valve)
  7. Pain
  8. Dyspnoea (difficult or laboured respiration)
  9. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
5 - 10 years:
  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Change of bowel habit
  3. Cholecystitis (infection of gallbladder)
  4. Colitis (inflammation of colon)
  5. Colonic polyp (extra part of colon tissue grow in intestine)
  6. Confusional state
  7. Cough
  8. Crohn's disease (condition that causes inflammation of the gastrointestinal tract)
  9. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
  10. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
10+ years:
  1. Abdominal distension
  2. Cardiac failure congestive
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. Headache (pain in head)
  6. Oedema peripheral (superficial swelling)
  7. Weight increased
not specified:
  1. Cardiac failure congestive
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  5. Dyspnoea (difficult or laboured respiration)
  6. Pain
  7. Weight increased
  8. Oedema peripheral (superficial swelling)
  9. Chest pain
  10. Anxiety

Most common drug interactions by gender *:

female:
  1. Weight increased
  2. Chest pain
  3. Oedema peripheral (superficial swelling)
  4. Blood glucose increased
  5. Pain
  6. Cardiac disorder
  7. Nausea (feeling of having an urge to vomit)
  8. Pneumonia
  9. Anxiety
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
male:
  1. Cardiac failure congestive
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Oedema peripheral (superficial swelling)
  4. Weight increased
  5. Acute myocardial infarction (acute heart attack)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Dizziness
  8. Weight decreased
  9. Pneumonia
  10. Asthenia (weakness)

Most common drug interactions by age *:

0-1:
  1. Balance disorder
  2. Bradycardia (abnormally slow heart action)
  3. Cholecystitis chronic (long lasting infection of gallbladder)
  4. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  5. Diabetic complication
  6. Dyspnoea (difficult or laboured respiration)
  7. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  8. Hypotension (abnormally low blood pressure)
  9. Nervous system disorder (a general class of medical conditions affecting the nervous system)
  10. Orthopnoea (shortness of breath (dyspnea) when lying down)
2-9:

n/a

10-19:
  1. Cardiac failure congestive
  2. Coronary artery bypass
  3. Dizziness
  4. Hypotonia (low muscle tone)
  5. Insomnia (sleeplessness)
  6. Pleural effusion (water on the lungs)
  7. Rash
  8. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  9. Weight decreased
20-29:
  1. Cardiac failure congestive
  2. Cardiomyopathy (weakening of the heart muscle)
  3. Chest pain
  4. Cough
  5. Dyspnoea (difficult or laboured respiration)
  6. Oedema (fluid collection in tissue)
  7. Pneumonia
  8. Pyrexia (fever)
  9. Vomiting
  10. Diabetes mellitus inadequate control
30-39:
  1. Cardiac failure congestive
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Chest pain
  4. Cerebrovascular disorder (disease of brain)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  7. Acute myocardial infarction (acute heart attack)
  8. Cardiac disorder
  9. Cardiomyopathy (weakening of the heart muscle)
  10. Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
40-49:
  1. Cardiac failure congestive
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Chest pain
  6. Dyspnoea (difficult or laboured respiration)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
  9. Coronary arterial stent insertion
  10. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
50-59:
  1. Pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Anxiety
  4. Emotional distress
  5. Insomnia (sleeplessness)
  6. Injury
  7. Acute myocardial infarction (acute heart attack)
  8. Arthralgia (joint pain)
  9. Fatigue (feeling of tiredness)
  10. Weight increased
60+:
  1. Cardiac failure congestive
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Cardiac disorder
  4. Acute myocardial infarction (acute heart attack)
  5. Pain
  6. Weight decreased
  7. Nausea (feeling of having an urge to vomit)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Diarrhoea
  10. Fatigue (feeling of tiredness)

* Approximation only. Some reports may have incomplete information.


Do you take Diovan and Avandia?

You are not alone:




Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Diovan and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Avandia and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Diovan and Avandia
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Diovan and Avandia (35,402 reports studied)



FDA reports used in this study


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