Elavil and Cosopt drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Elavil and Cosopt. Common interactions include abdominal pain upper among females and skin lesion among males.
The phase IV clinical study analyzes what interactions people who take Elavil and Cosopt have. It is created by eHealthMe based on reports of 10 people who take Elavil and Cosopt from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
10 people who take Elavil and Cosopt together, and have interactions are studied.
What is Elavil?
Elavil has active ingredients of amitriptyline hydrochloride. It is often used in depression. eHealthMe is studying from 19,551 Elavil users for its effectiveness, alternative drugs and more.
What is Cosopt?
Cosopt has active ingredients of dorzolamide hydrochloride; timolol maleate. It is often used in glaucoma. eHealthMe is studying from 8,369 Cosopt users for its effectiveness, alternative drugs and more.
Number of Elavil and Cosopt reports submitted per year:

Common Elavil and Cosopt drug interactions by gender *:
female:
- Abdominal pain upper
- Dyspepsia
- Myalgia
- Myopathy
- Nausea
- Tooth infection
male:
- Skin lesion
- Anhedonia
- Hypoglycaemia
- Metabolic encephalopathy
- Nasopharyngitis
- Osteopenia
- Pain
- Rash
- Renal impairment
- Sexual dysfunction
Common Elavil and Cosopt drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Malaise
- Skin lesion
30-39:
n/a
40-49:
n/a
50-59:
- Anhedonia
- Anxiety
- Asthenia
- Chronic kidney disease
- Emotional distress
- Hip fracture
- Osteopenia
- Pain
- Renal impairment
- Sexual dysfunction
60+:
- Aspartate aminotransferase decreased
- Blood alkaline phosphatase increased
- Dyspepsia
- Incoherent
- Mental status changes
- Multiple drug overdose
- Myalgia
- Myopathy
- Nausea
- Nuclear magnetic resonance imaging brain
Common conditions people have *:
- High Blood Pressure: 3 people, 30.00%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 2 people, 20.00%
- Bone Pain: 2 people, 20.00%
- Deformity (disfigurement): 2 people, 20.00%
- Dementia Alzheimer's Type (loss of mental ability with alzheimer's symptom): 2 people, 20.00%
- Diabetes: 2 people, 20.00%
- Erection Problems: 2 people, 20.00%
- Herpes Virus Infection: 2 people, 20.00%
- High Blood Cholesterol: 2 people, 20.00%
- Urinary Retention (the inability to completely or partially empty the bladder): 2 people, 20.00%
* Approximation only. Some reports may have incomplete information.
Do you take Elavil and Cosopt?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Li W, Lamichhane J, "From Heartbreak to Left Bundle Branch Block: A Case of Amitriptyline Overdose", American Journal of Therapeutics, 2017 Sep .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Elavil and Cosopt:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Elavil side effects:
- Pain: 2,351 reports
- Fatigue (feeling of tiredness): 2,006 reports
- Drug ineffective: 1,853 reports
- Headache (pain in head): 1,772 reports
- Stress and anxiety: 1,717 reports
- Weakness: 1,706 reports
- Joint pain: 1,613 reports
Browse all side effects of Elavil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Cosopt side effects:
- Drug ineffective: 523 reports
- Eye pain: 395 reports
- Weakness: 354 reports
- Breathing difficulty: 342 reports
- Death: 335 reports
- Fatigue (feeling of tiredness): 326 reports
Browse all side effects of Cosopt:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Elavil interactions:
- Elavil and Prednisone: 2,215 reports
- Elavil and Neurontin: 2,211 reports
- Elavil and Synthroid: 1,815 reports
- Elavil and Lyrica: 1,771 reports
- Elavil and Lasix: 1,733 reports
- Elavil and Aspirin: 1,526 reports
- Elavil and Methotrexate: 1,515 reports
- Elavil and Prilosec: 1,471 reports
- Elavil and Xanax: 1,466 reports
- Elavil and Lipitor: 1,448 reports
Browse all interactions between Elavil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Cosopt interactions:
- Cosopt and Xalatan: 1,380 reports
- Cosopt and Alphagan: 1,121 reports
- Cosopt and Lumigan: 834 reports
- Cosopt and Aspirin: 750 reports
- Cosopt and Alphagan p: 580 reports
- Cosopt and Latanoprost: 469 reports
- Cosopt and Travatan: 458 reports
- Cosopt and Prednisone: 391 reports
- Cosopt and Lisinopril: 354 reports
- Cosopt and Lipitor: 348 reports
Browse all interactions between Cosopt and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on amitriptyline hydrochloride and dorzolamide hydrochloride; timolol maleate (the active ingredients of Elavil and Cosopt, respectively), and Elavil and Cosopt (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Elavil and Cosopt.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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