Eliquis and Aspirin drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Eliquis and Aspirin together. This study is created by eHealthMe based on reports of 3,689 people who take Eliquis and Aspirin from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on apixaban and aspirin (the active ingredients of Eliquis and Aspirin, respectively), and Eliquis and Aspirin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Eliquis?

Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. (latest outcomes from Eliquis 52,651 users)

What is Aspirin?

Aspirin has active ingredients of aspirin. It is often used in blood clots. (latest outcomes from Aspirin 385,580 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 10, 2019

3,689 people who take Eliquis, Aspirin are studied.


Number of reports submitted per year:

Eliquis and Aspirin drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Cerebral haemorrhage (bleeding within the brain)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Fall
  4. Aphasia (damage to the parts of the brain that control language)
  5. Haemorrhage (bleeding)
  6. Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
  7. Haematoma (collection of blood outside the blood vessels)
  8. Anaemia (lack of blood)
  9. Hemiplegia (paralysis of one side of the body)
  10. Abdominal pain
1 - 6 months:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Anaemia (lack of blood)
  5. Muscular weakness (muscle weakness)
  6. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  7. Cerebral haemorrhage (bleeding within the brain)
  8. Dizziness
  9. Epistaxis (bleed from the nose)
  10. Abdominal pain
6 - 12 months:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Haemorrhage (bleeding)
  5. Anaemia (lack of blood)
  6. Cough
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Purpura (purplish discoloration of the skin)
  9. Respiratory failure (inadequate gas exchange by the respiratory system)
  10. Gastric antral vascular ectasia (blood vessels in the lining of the stomach become fragile and become prone to rupture and bleeding)
1 - 2 years:
  1. Anaemia (lack of blood)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Gastric ulcer haemorrhage (bleeding ulcer of stomach)
  4. Gingival bleeding (bleeding gums)
  5. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  6. Cardiac failure congestive
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Death
  9. Dyspnoea (difficult or laboured respiration)
  10. Gallbladder disorder
2 - 5 years:
  1. Abdominal pain
  2. Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
  3. Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Cardiogenic shock (inadequate circulation of blood)
  7. Cerebral haemorrhage (bleeding within the brain)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Colitis (inflammation of colon)
  10. Diarrhoea
5 - 10 years:
  1. Fall
  2. Cardiac failure congestive
  3. Dehydration (dryness resulting from the removal of water)
  4. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  5. Acute hepatic failure
  6. Acute left ventricular failure (heart attack)
  7. Arrhythmia (irregular heartbeat)
  8. Arthralgia (joint pain)
  9. Asthenia (weakness)
  10. Blood creatinine increased
10+ years:
  1. Asthenia (weakness)
  2. Blood creatinine increased
  3. Renal failure (kidney dysfunction)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
  6. Abnormal dreams
  7. Aggression
  8. Chest discomfort
  9. Confusional state
  10. Constipation
not specified:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Dyspnoea (difficult or laboured respiration)
  3. Dizziness
  4. Fatigue (feeling of tiredness)
  5. Fall
  6. Asthenia (weakness)
  7. Haemorrhage (bleeding)
  8. Diarrhoea
  9. Anaemia (lack of blood)
  10. Epistaxis (bleed from the nose)

Most common drug interactions by gender *:

female:
  1. Rash
  2. Thrombosis (formation of a blood clot inside a blood vessel)
  3. Drug ineffective
  4. Peripheral swelling
  5. Rectal haemorrhage (bleeding from anus)
  6. Pain
  7. Pain in extremity
  8. Gait disturbance
  9. Vomiting
  10. Haemoglobin decreased
male:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Dyspnoea (difficult or laboured respiration)
  3. Epistaxis (bleed from the nose)
  4. Hypotension (abnormally low blood pressure)
  5. Pneumonia
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Decreased appetite
  8. Nausea (feeling of having an urge to vomit)
  9. Haemoglobin decreased
  10. Drug ineffective

Most common drug interactions by age *:

0-1:

n/a

2-9:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
10-19:

n/a

20-29:
  1. Dizziness
  2. Tooth infection
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Compartment syndrome (painful condition that occurs when pressure within the muscles builds to dangerous levels)
  5. Constipation
  6. Haematoma (collection of blood outside the blood vessels)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Suicidal ideation
40-49:
  1. Asthenia (weakness)
  2. Cataract (clouding of the lens inside the eye)
  3. Hypercholesterolaemia (high levels of cholesterol in the blood)
  4. Anxiety
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Dehydration (dryness resulting from the removal of water)
  7. Aphasia (damage to the parts of the brain that control language)
  8. Body height decreased
  9. Confusional state
  10. Migraine (headache)
50-59:
  1. Epistaxis (bleed from the nose)
  2. Fatigue (feeling of tiredness)
  3. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  4. Fall
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Hypotension (abnormally low blood pressure)
  7. Abdominal pain
  8. Aphasia (damage to the parts of the brain that control language)
  9. Drug hypersensitivity
  10. Headache (pain in head)
60+:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Dyspnoea (difficult or laboured respiration)
  3. Nausea (feeling of having an urge to vomit)
  4. Death
  5. Haemoglobin decreased
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Epistaxis (bleed from the nose)
  8. Weight decreased
  9. Drug ineffective
  10. Decreased appetite

* Approximation only. Some reports may have incomplete information.

Do you take Eliquis and Aspirin?


You are not alone:




Related publications that referenced our studies


Results from eHealthMe (non-FDA) reports of taking Eliquis and Aspirin together

Drug effectiveness (drug is found to be effective) over time *:
Eliquis:
  • < 1 month: 0.0% (0 of 0 people)
  • 1 - 6 months: 0.0% (0 of 2 people)
  • 6 - 12 months: 100% (2 of 2 people)
  • 1 - 2 years: 50% (1 of 2 people)
  • 2 - 5 years: 0.0% (0 of 1 people)
  • 5 - 10 years: 100% (1 of 1 people)
  • 10+ years: 0.0% (0 of 0 people)
  • not specified: 0.0% (0 of 0 people)
Aspirin:
  • < 1 month: 100% (1 of 1 people)
  • 1 - 6 months: 0.0% (0 of 0 people)
  • 6 - 12 months: 0.0% (0 of 0 people)
  • 1 - 2 years: 100% (2 of 2 people)
  • 2 - 5 years: 66% (2 of 3 people)
  • 5 - 10 years: 0.0% (0 of 0 people)
  • 10+ years: 50% (1 of 2 people)
  • not specified: 0.0% (0 of 0 people)
Drug effectiveness (drug is found to be effective) by gender *:
Eliquis:
  • female: 33% (1 of 3 people)
  • male: 60% (3 of 5 people)
Aspirin:
  • female: 66% (2 of 3 people)
  • male: 80% (4 of 5 people)
Drug effectiveness (drug is found to be effective) by age *:
Eliquis:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 0.0% (0 of 0 people)
  • 40-49: 100.0% (1 of 1 people)
  • 50-59: 0.0% (0 of 1 people)
  • 60+: 50.0% (3 of 6 people)
Aspirin:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 0.0% (0 of 0 people)
  • 40-49: 100.0% (1 of 1 people)
  • 50-59: 100.0% (1 of 1 people)
  • 60+: 66.0% (4 of 6 people)
Race of the people *:
  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 3.45 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 96.55 %

* Approximation only.


Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Eliquis and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Aspirin and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Eliquis and Aspirin
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Eliquis and Aspirin (54,987 reports studied)



FDA reports used in this study


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