Estring and Colace drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Estring and Colace. Common interactions include drug effect decreased among females and ankle fracture among males.
The phase IV clinical study analyzes what interactions people who take Estring and Colace have. It is created by eHealthMe based on reports of 19 people who take Estring and Colace from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
19 people who take Estring and Colace together, and have interactions are studied.
What is Estring?
Estring has active ingredients of estradiol. eHealthMe is studying from 4,546 Estring users for its effectiveness, alternative drugs and more.
What is Colace?
Colace has active ingredients of docusate . It is often used in constipation. eHealthMe is studying from 38,011 Colace users for its effectiveness, alternative drugs and more.
Number of Estring and Colace reports submitted per year:

Common Estring and Colace drug interactions by gender *:
female:
- Drug effect decreased
- Drug intolerance
- Dry mouth
- Dry throat
- Dysstasia
- Dysuria
- Endocrine disorder
- Facial nerve disorder
- Gastrooesophageal reflux disease
- Depression
male:
- Ankle fracture
- Blood cholesterol increased
- Osteoporosis
- Pelvic fracture
- Pyrexia
- Rib fracture
- Stress fracture
- Urticaria
- Vulvovaginal dryness
- Weight decreased
Common Estring and Colace drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Ankle fracture
- Blood cholesterol increased
- Bone loss
- Bone marrow oedema
- Bone pain
- Cervical vertebral fracture
- Fatigue
- Fibromyalgia
- Fracture
- Oedema
50-59:
- Endocrine disorder
- Facial nerve disorder
- Fatigue
- General physical condition
- Inflammatory bowel disease
- Insomnia
- Jaw disorder
- Metastases to liver
- Metastases to lung
- Muscle spasms
60+:
- Atrial fibrillation
- Pneumonia
- Abnormal behaviour
- Agitation
- Anxiety
- Arthralgia
- Back pain
- Body height decreased
- Chills
- Colitis ischaemic
Common conditions people have *:
- Pain: 8 people, 42.11%
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 21.05%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 21.05%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 15.79%
- Hypersensitivity: 3 people, 15.79%
- Breast Cancer: 3 people, 15.79%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 15.79%
- Atrophic Vulvovaginitis (inflammation of the vulva): 2 people, 10.53%
- Depression: 2 people, 10.53%
- Hair Loss: 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Estring and Colace?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Estring and Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Estring side effects:
- Drug ineffective: 647 reports
- Pain: 234 reports
- Urinary tract infection: 232 reports
- Headache (pain in head): 178 reports
- Vaginal discharge: 177 reports
- Vaginal bleeding: 160 reports
Browse all side effects of Estring:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Colace side effects:
- Fatigue (feeling of tiredness): 3,903 reports
- Pain: 2,982 reports
- Breathing difficulty: 2,925 reports
- Weakness: 2,887 reports
- Diarrhea: 2,555 reports
- Constipation: 2,467 reports
Browse all side effects of Colace:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Estring interactions:
- Estring and Synthroid: 269 reports
- Estring and Premarin: 214 reports
- Estring and Vitamin d: 182 reports
- Estring and Aspirin: 178 reports
- Estring and Omeprazole: 132 reports
- Estring and Simvastatin: 121 reports
- Estring and Gabapentin: 119 reports
- Estring and Zyrtec: 115 reports
- Estring and Prednisone: 105 reports
Browse all interactions between Estring and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Colace interactions:
- Colace and Aspirin: 8,891 reports
- Colace and Tylenol: 5,969 reports
- Colace and Miralax: 5,239 reports
- Colace and Lasix: 4,999 reports
- Colace and Zofran: 4,793 reports
- Colace and Vitamin d: 4,768 reports
- Colace and Prednisone: 4,641 reports
- Colace and Gabapentin: 3,970 reports
- Colace and Omeprazole: 3,945 reports
- Colace and Lisinopril: 3,871 reports
Browse all interactions between Colace and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estradiol and docusate (the active ingredients of Estring and Colace, respectively), and Estring and Colace (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Estring and Colace.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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