Estring and Zofran drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Estring and Zofran. Common interactions include interstitial lung disease among females.
The phase IV clinical study analyzes what interactions people who take Estring and Zofran have. It is created by eHealthMe based on reports of 30 people who take Estring and Zofran from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
30 people who take Estring and Zofran together, and have interactions are studied.
What is Estring?
Estring has active ingredients of estradiol. eHealthMe is studying from 4,546 Estring users for its effectiveness, alternative drugs and more.
What is Zofran?
Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 84,340 Zofran users for its effectiveness, alternative drugs and more.
Number of Estring and Zofran reports submitted per year:

Common Estring and Zofran drug interactions by gender *:
female:
- Interstitial lung disease
- Pain
- Candidiasis
- Device related infection
- Sinus congestion
- Ear infection fungal
- Fatigue
- Otitis externa
- Otitis media
- Arthritis
male:
n/a
Common Estring and Zofran drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Haemorrhoids
- Hypercholesterolaemia
- Irritable bowel syndrome
- Learning disorder
- Lethargy
- Memory impairment
- Migraine
- Muscle spasms
- Neuropathy peripheral
- Osteoporosis
60+:
- Arthritis
- Azotaemia
- Fall
- Fatigue
- Glossodynia
- Headache
- Herpes virus infection
- Hyperhidrosis
- Hypervolaemia
- Hypoxia
Common conditions people have *:
- Immunodeficiency Common Variable: 14 people, 46.67%
- Pain: 4 people, 13.33%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 13.33%
- Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 10.00%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 6.67%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 6.67%
- Insomnia (sleeplessness): 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Estring and Zofran?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Estring and Zofran:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Estring side effects:
- Drug ineffective: 647 reports
- Pain: 234 reports
- Urinary tract infection: 232 reports
- Headache (pain in head): 178 reports
- Vaginal discharge: 177 reports
- Vaginal bleeding: 160 reports
Browse all side effects of Estring:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Zofran side effects:
- Fatigue (feeling of tiredness): 8,640 reports
- Nausea and vomiting: 8,106 reports
- Diarrhea: 7,770 reports
- Indigestion: 7,679 reports
- Pain: 7,289 reports
- Stress and anxiety: 5,464 reports
Browse all side effects of Zofran:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Estring interactions:
- Estring and Synthroid: 269 reports
- Estring and Premarin: 214 reports
- Estring and Vitamin d: 182 reports
- Estring and Aspirin: 178 reports
- Estring and Omeprazole: 132 reports
- Estring and Simvastatin: 121 reports
- Estring and Gabapentin: 119 reports
- Estring and Zyrtec: 115 reports
- Estring and Prednisone: 105 reports
Browse all interactions between Estring and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Zofran interactions:
- Zofran and Aspirin: 10,735 reports
- Zofran and Tylenol: 9,367 reports
- Zofran and Prednisone: 8,033 reports
- Zofran and Protonix: 7,650 reports
- Zofran and Ativan: 7,514 reports
- Zofran and Vitamin d: 7,404 reports
- Zofran and Gabapentin: 7,142 reports
- Zofran and Omeprazole: 7,114 reports
- Zofran and Lasix: 6,995 reports
- Zofran and Benadryl: 6,668 reports
Browse all interactions between Zofran and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on estradiol and ondansetron hydrochloride (the active ingredients of Estring and Zofran, respectively), and Estring and Zofran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Estring and Zofran.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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