Flexeril and Levofloxacin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Flexeril and Levofloxacin. Common interactions include arrhythmia among females and gastrointestinal haemorrhage among males.
The phase IV clinical study analyzes what interactions people who take Flexeril and Levofloxacin have. It is created by eHealthMe based on reports of 45 people who take Flexeril and Levofloxacin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
45 people who take Flexeril and Levofloxacin together, and have interactions are studied.
What is Flexeril?
Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 36,937 Flexeril users for its effectiveness, alternative drugs and more.
What is Levofloxacin?
Levofloxacin has active ingredients of levofloxacin; sodium chloride. It is often used in sinusitis. eHealthMe is studying from 16,305 Levofloxacin users for its effectiveness, alternative drugs and more.
Number of Flexeril and Levofloxacin reports submitted per year:

Common Flexeril and Levofloxacin drug interactions by gender *:
female:
- Arrhythmia
- General physical health deterioration
- Palpitations
- Chills
- Cholelithiasis
- Diarrhoea
- Fall
- Fatigue
- Headache
- Hypotension
male:
- Gastrointestinal haemorrhage
- Anaemia
- Cataract
- Cellulitis
- Cerebral ischaemia
- Chronic obstructive pulmonary disease
- Decreased interest
- Dental caries
- Diabetes mellitus
- Diverticulum intestinal
Common Flexeril and Levofloxacin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Chills
- Conjunctivitis
- Cytokine release syndrome
- Diarrhoea
- Hyperhidrosis
- Hypotension
- Nausea
- Oral dysaesthesia
- Periorbital oedema
- Photophobia
20-29:
- Pain
- Anxiety
- Arrhythmia
- Chest discomfort
- Chest pain
- Emotional distress
- General physical health deterioration
- Mental disorder
- Palpitations
- Tachycardia
30-39:
- Depression
40-49:
- Fatigue
- Headache
- Infusion site erythema
- Nausea
50-59:
- Aphthous stomatitis
- Arteriosclerosis
- Asthma
- Blood glucose fluctuation
- Bone disorder
- Bronchitis
- Cataract
- Cellulitis
- Cerebral ischaemia
- Chronic obstructive pulmonary disease
60+:
- Gastrointestinal haemorrhage
- Pain
- Confusional state
- Gait disturbance
- Heparin-induced thrombocytopenia
- Abasia
- Agranulocytosis
- Altered state of consciousness
- Amnesia
- Anaemia
Common conditions people have *:
- Urinary Tract Infection: 7 people, 15.56%
- Hypersensitivity: 5 people, 11.11%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 11.11%
- Pain: 4 people, 8.89%
- Migraine (headache): 4 people, 8.89%
- Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 8.89%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 6.67%
- Constipation: 3 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Flexeril and Levofloxacin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Flexeril (36,937 reports)
- Levofloxacin (16,305 reports)
Common Flexeril and Levofloxacin interactions:
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 9 reports
- Back pain: 8 reports
- Diarrhea: 5 reports
- Joint pain: 4 reports
Browse all drug interactions of Flexeril and Levofloxacin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Flexeril side effects:
- Pain: 4,126 reports
- Fatigue (feeling of tiredness): 3,092 reports
- Stress and anxiety: 2,879 reports
- Headache (pain in head): 2,664 reports
- Breathing difficulty: 2,356 reports
- Depression: 2,304 reports
Browse all side effects of Flexeril:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levofloxacin side effects:
- Fever: 1,445 reports
- Pneumonia: 1,220 reports
- Thrombocytopenia (decrease of platelets in blood): 1,037 reports
- Rashes (redness): 797 reports
- Hypotension (abnormally low blood pressure): 711 reports
- Weakness: 692 reports
Browse all side effects of Levofloxacin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Flexeril interactions:
- Flexeril and Aspirin: 4,393 reports
- Flexeril and Lyrica: 3,969 reports
- Flexeril and Xanax: 3,636 reports
- Flexeril and Prednisone: 3,575 reports
- Flexeril and Neurontin: 3,554 reports
- Flexeril and Gabapentin: 3,536 reports
- Flexeril and Nexium: 3,322 reports
- Flexeril and Cymbalta: 3,308 reports
- Flexeril and Lisinopril: 3,228 reports
- Flexeril and Prilosec: 3,134 reports
Browse all interactions between Flexeril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levofloxacin interactions:
- Levofloxacin and Furosemide: 1,314 reports
- Levofloxacin and Fluconazole: 1,216 reports
- Levofloxacin and Prednisone: 1,112 reports
- Levofloxacin and Acetaminophen: 1,064 reports
- Levofloxacin and Omeprazole: 1,060 reports
- Levofloxacin and Aspirin: 975 reports
- Levofloxacin and Lasix: 962 reports
- Levofloxacin and Lopurin: 884 reports
- Levofloxacin and Acyclovir: 867 reports
- Levofloxacin and Dexamethasone: 857 reports
Browse all interactions between Levofloxacin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cyclobenzaprine hydrochloride and levofloxacin; sodium chloride (the active ingredients of Flexeril and Levofloxacin, respectively), and Flexeril and Levofloxacin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Flexeril and Levofloxacin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Gliclazide and Pco2 Decreased - a second ago
- Psoriasis and Arthropod Bite - 2 seconds ago
- Mepron and Revlimid drug interaction - 5 seconds ago
- Zoledronic Acid and Buspirone Hcl drug interaction - 7 seconds ago
- Lexapro and Antinuclear Antibody Positive - 15 seconds ago
- Levetiracetam and Depo-Testosterone drug interaction - 19 seconds ago
- Myasthenia Gravis and Hyperhidrosis - 31 seconds ago
- Benylin and Stools - Watery - 32 seconds ago
- Benylin and Diarrhea - 32 seconds ago
- Mepron and Lopurin drug interaction - 46 seconds ago