Gemcitabine and Fluorouracil drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Gemcitabine and Fluorouracil. Common interactions include metastases to liver among females and neutropenia among males.
The phase IV clinical study analyzes what interactions people who take Gemcitabine and Fluorouracil have. It is created by eHealthMe based on reports of 927 people who take Gemcitabine and Fluorouracil from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
927 people who take Gemcitabine and Fluorouracil together, and have interactions are studied.
What is Gemcitabine?
Gemcitabine has active ingredients of gemcitabine. eHealthMe is studying from 23,262 Gemcitabine users for its effectiveness, alternative drugs and more.
What is Fluorouracil?
Fluorouracil has active ingredients of fluorouracil. It is often used in colon cancer metastatic. eHealthMe is studying from 84,340 Fluorouracil users for its effectiveness, alternative drugs and more.
Number of Gemcitabine and Fluorouracil reports submitted per year:

Gemcitabine and Fluorouracil drug interactions by gender *:
Gemcitabine and Fluorouracil drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Gemcitabine and Fluorouracil?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Gemcitabine (23,262 reports)
- Fluorouracil (84,340 reports)
Common Gemcitabine and Fluorouracil interactions:
- Chills (felling of cold): 13 reports
Browse all drug interactions of Gemcitabine and Fluorouracil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Gemcitabine side effects:
- Thrombocytopenia (decrease of platelets in blood): 2,453 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1,947 reports
- Fever: 1,527 reports
- Fatigue (feeling of tiredness): 1,291 reports
- Nausea and vomiting: 1,202 reports
- Death: 1,144 reports
- Diarrhea: 1,140 reports
Browse all side effects of Gemcitabine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Fluorouracil side effects:
- Diarrhea: 8,012 reports
- Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 6,985 reports
- Nausea and vomiting: 5,556 reports
- Thrombocytopenia (decrease of platelets in blood): 4,679 reports
- Fever: 4,562 reports
- Fatigue (feeling of tiredness): 3,898 reports
Browse all side effects of Fluorouracil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Gemcitabine interactions:
- Gemcitabine and Cisplatin: 5,201 reports
- Gemcitabine and Carboplatin: 4,167 reports
- Gemcitabine and Abraxane: 2,886 reports
- Gemcitabine and Paclitaxel: 2,466 reports
- Gemcitabine and Oxaliplatin: 2,026 reports
- Gemcitabine and Docetaxel: 1,681 reports
- Gemcitabine and Cyclophosphamide: 1,391 reports
- Gemcitabine and Dexamethasone: 1,207 reports
- Gemcitabine and Ondansetron: 1,121 reports
- Gemcitabine and Capecitabine: 1,084 reports
Browse all interactions between Gemcitabine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Fluorouracil interactions:
- Fluorouracil and Oxaliplatin: 28,471 reports
- Fluorouracil and Leucovorin calcium: 13,243 reports
- Fluorouracil and Avastin: 10,055 reports
- Fluorouracil and Cisplatin: 9,725 reports
- Fluorouracil and Cyclophosphamide: 8,252 reports
- Fluorouracil and Docetaxel: 5,306 reports
- Fluorouracil and Eloxatin: 3,511 reports
- Fluorouracil and Ondansetron: 3,413 reports
- Fluorouracil and Irinotecan hydrochloride: 3,284 reports
- Fluorouracil and Capecitabine: 3,100 reports
Browse all interactions between Fluorouracil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on gemcitabine and fluorouracil (the active ingredients of Gemcitabine and Fluorouracil, respectively), and Gemcitabine and Fluorouracil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Gemcitabine and Fluorouracil.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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