Imbruvica and Amitiza drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imbruvica and Amitiza. Common interactions include central nervous system lymphoma among females and asthenia among males.

The phase IV clinical study analyzes what interactions people who take Imbruvica and Amitiza have. It is created by eHealthMe based on reports of 18 people who take Imbruvica and Amitiza from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 30, 2022

18 people who take Imbruvica and Amitiza together, and have interactions are studied.

What is Imbruvica?

Imbruvica has active ingredients of ibrutinib. It is often used in chronic lymphocytic leukemia (cll). eHealthMe is studying from 50,134 Imbruvica users for its effectiveness, alternative drugs and more.

What is Amitiza?

Amitiza has active ingredients of lubiprostone. It is often used in constipation. eHealthMe is studying from 9,586 Amitiza users for its effectiveness, alternative drugs and more.

Number of Imbruvica and Amitiza reports submitted per year:

Common Imbruvica and Amitiza drug interactions by gender *:

female:

Central nervous system lymphoma
Disease progression
Mycosis fungoides
Death
Pleural effusion
Atrial fibrillation
Blister
Dysgeusia
Epistaxis
Gingival bleeding

male:

Asthenia
Fall
Tooth disorder
Tooth extraction
Influenza
Nasopharyngitis
Postoperative adhesion
Cardiac disorder
Nephrolithiasis
Pancreatitis

Common Imbruvica and Amitiza drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Local swelling
Neck pain
Pharyngeal oedema
Pyrexia

60+:

Central nervous system lymphoma
Disease progression
Mouth haemorrhage
Abnormal behaviour
Pancreatic carcinoma
Tooth disorder
Tooth extraction
Influenza
Nasopharyngitis
Pleural effusion

Common conditions people have *:

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 12 people, 66.67%
Mantle Cell Lymphoma (cancer of lymphocytes, a type of white blood cell): 2 people, 11.11%
T-Cell Lymphoma (a blood cell cancer): 1 person, 5.56%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 1 person, 5.56%
Chronic Lymphocytic Leukaemia Stage 4 (blood cell cancer with too few blood platelets), with or without anaemia, enlarged lymph nodes, spleen, or liver): 1 person, 5.56%
B-Cell Small Lymphocytic Lymphoma (blood cancer affecting b cells): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Imbruvica and Amitiza?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.