Invega and Dilantin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Invega and Dilantin. Common interactions include hepatocellular damage among females and arrhythmia among males.
The phase IV clinical study analyzes what interactions people who take Invega and Dilantin have. It is created by eHealthMe based on reports of 13 people who take Invega and Dilantin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
13 people who take Invega and Dilantin together, and have interactions are studied.
What is Invega?
Invega has active ingredients of paliperidone. It is often used in bipolar disorder. eHealthMe is studying from 30,825 Invega users for its effectiveness, alternative drugs and more.
What is Dilantin?
Dilantin has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 20,839 Dilantin users for its effectiveness, alternative drugs and more.
Number of Invega and Dilantin reports submitted per year:

Common Invega and Dilantin drug interactions by gender *:
female:
- Hepatocellular damage
- Hypospadias
- Muscle spasms
- Oedema peripheral
- Pancreatitis
- Renal injury
- Suicide attempt
- Galactorrhoea
- Hyperprolactinaemia
- Headache
male:
- Arrhythmia
- Death
Common Invega and Dilantin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Death
50-59:
- Breast swelling
- Oedema peripheral
60+:
- Muscle spasms
Common conditions people have *:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 38.46%
- Stress And Anxiety: 3 people, 23.08%
- Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 23.08%
- Borderline Personality Disorder: 3 people, 23.08%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 15.38%
- Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 2 people, 15.38%
- Migraine (headache): 2 people, 15.38%
- Schizoaffective Disorder (a mental disorder characterized by disordered thought): 1 person, 7.69%
- Psychotic Disorder: 1 person, 7.69%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Invega and Dilantin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Invega and Dilantin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Invega side effects:
- Gynecomastia (enlargement of the gland tissue of the male breast): 6,878 reports
- Nipple discharge - abnormal: 2,301 reports
- Weight increased: 1,352 reports
- Drug ineffective: 1,101 reports
- Weight loss: 659 reports
Browse all side effects of Invega:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Dilantin side effects:
- Fatigue (feeling of tiredness): 1,181 reports
- Drug ineffective: 1,155 reports
- Weakness: 1,057 reports
- Headache (pain in head): 1,046 reports
- Dizziness: 926 reports
Browse all side effects of Dilantin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Invega interactions:
- Invega and Risperdal: 20,942 reports
- Invega and Risperidone: 2,731 reports
- Invega and Invega sustenna: 1,871 reports
- Invega and Risperdal consta: 1,027 reports
- Invega and Abilify: 952 reports
- Invega and Zyprexa: 826 reports
- Invega and Seroquel: 809 reports
- Invega and Clozapine: 498 reports
- Invega and Olanzapine: 487 reports
- Invega and Latuda: 472 reports
Browse all interactions between Invega and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Dilantin interactions:
- Dilantin and Keppra: 1,613 reports
- Dilantin and Neurontin: 1,164 reports
- Dilantin and Depakote: 994 reports
- Dilantin and Synthroid: 945 reports
- Dilantin and Lamictal: 934 reports
- Dilantin and Aspirin: 868 reports
- Dilantin and Lasix: 837 reports
- Dilantin and Lipitor: 825 reports
- Dilantin and Coumadin: 788 reports
- Dilantin and Lisinopril: 760 reports
Browse all interactions between Dilantin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on paliperidone and phenytoin sodium (the active ingredients of Invega and Dilantin, respectively), and Invega and Dilantin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Invega and Dilantin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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