Irbesartan and Metformin drug interactions - from FDA reports


Drug interactions are reported among people who take Irbesartan and Metformin together. This study is created by eHealthMe based on reports of 2,266 people who take Irbesartan and Metformin from FDA, and is updated regularly.

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On Jan, 19, 2019

2,266 people who take Irbesartan, Metformin are studied.


Number of reports submitted per year:

Irbesartan and Metformin drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Pyrexia (fever)
  2. Blood albumin decreased
  3. Blood urea increased
  4. C-reactive protein increased
  5. Cough
  6. Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
  7. Haemoglobin decreased
  8. Hypoglycaemia (deficiency of glucose in the bloodstream)
  9. Hypotension (abnormally low blood pressure)
  10. Incision site pain
1 - 6 months:
  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Hyperkalaemia (damage to or disease of the kidney)
  4. Anxiety
  5. Hypoglycaemic coma (coma due to deficiency of glucose in the bloodstream)
  6. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  7. Anaemia haemolytic autoimmune (condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  8. Bone disorder
  9. Cardiogenic shock (inadequate circulation of blood)
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
6 - 12 months:
  1. Renal failure (kidney dysfunction)
  2. Vomiting
  3. Asthenia (weakness)
  4. Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances)
  5. Colorectal cancer metastatic (cancer of colon and rectal spreads to other parts)
  6. Diarrhoea
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Lactic acidosis (low ph in body tissues)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
1 - 2 years:
  1. Leukocytoclastic vasculitis (inflammation of small blood vessels (usually post-capillary venules in the dermis), characterized by palpable purpura)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Alveolitis allergic (inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Dyslipidaemia (abnormal amount of lipids)
  7. Ejection fraction decreased (systolic heart failure)
  8. Mitral valve incompetence (inefficient heart valve)
  9. Pain
  10. Renal cyst (kidney cyst)
2 - 5 years:
  1. Renal failure acute (rapid kidney dysfunction)
  2. Amaurosis (partial or total blindness without visible change in the eye)
  3. Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
  4. Hyperkalaemia (damage to or disease of the kidney)
  5. Altered state of consciousness (altered state of mind)
  6. Anaemia haemolytic autoimmune (condition in which the immune system attacks the red blood cells, resulting in fewer of these oxygen-transporting cells)
  7. Anxiety
  8. Aphasia (damage to the parts of the brain that control language)
  9. Bone disorder
  10. Cardiogenic shock (inadequate circulation of blood)
5 - 10 years:
  1. Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)
  2. Sudden death
  3. Confusional state
  4. Aphasia (damage to the parts of the brain that control language)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  7. Concomitant disease progression (progress in accompanying disease)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Blood glucose increased
  10. Hypoaesthesia (reduced sense of touch or sensation)
10+ years:
  1. Femur fracture
  2. Anxiety
  3. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  4. Pneumonia streptococcal (pneumonia, caused by streptococcus pneumoniae)
  5. Brain stem syndrome
  6. Confusional state
  7. Constipation
  8. Death
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea
not specified:
  1. Diarrhoea
  2. Lactic acidosis (low ph in body tissues)
  3. Dyspnoea (difficult or laboured respiration)
  4. Renal failure acute (rapid kidney dysfunction)
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Nausea (feeling of having an urge to vomit)
  7. Hypotension (abnormally low blood pressure)
  8. Vomiting
  9. Asthenia (weakness)
  10. Fatigue (feeling of tiredness)

Most common drug interactions by gender *:

female:
  1. Nausea (feeling of having an urge to vomit)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fall
  4. Vomiting
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Dehydration (dryness resulting from the removal of water)
  7. Hypotension (abnormally low blood pressure)
  8. Drug ineffective
  9. Confusional state
  10. Weight decreased
male:
  1. Dyspnoea (difficult or laboured respiration)
  2. Diarrhoea
  3. Blood creatinine increased
  4. Weight decreased
  5. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  6. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  7. Asthenia (weakness)
  8. Decreased appetite
  9. Anaemia (lack of blood)
  10. Fatigue (feeling of tiredness)

Most common drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:
  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney)
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Hypotension (abnormally low blood pressure)
  5. Intentional overdose
  6. Overdose
  7. Dizziness
  8. Pain
  9. Abdominal discomfort
  10. Acute myocardial infarction (acute heart attack)
20-29:
  1. Nausea (feeling of having an urge to vomit)
  2. Normal newborn
  3. Vomiting
  4. Aphasia (damage to the parts of the brain that control language)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Confusional state
  7. Gallbladder injury
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  10. Abdominal pain upper
30-39:
  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Drug ineffective
  3. Maternal exposure during pregnancy (use of substance during pregnancy)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Bone pain
  8. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  9. Encephalopathy (functioning of the brain is affected by some agent or condition)
  10. Malaise (a feeling of general discomfort or uneasiness)
40-49:
  1. Unresponsive to stimuli
  2. Constipation
  3. Diverticular perforation (serious gastrointestinal condition in which the intestine's walls are perforated)
  4. Gastric disorder (disease of stomach)
  5. Haematemesis (vomiting of blood)
  6. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)
  7. Salivary hypersecretion (excess saliva secretion)
  8. Lactic acidosis (low ph in body tissues)
  9. Diarrhoea
  10. Hypotension (abnormally low blood pressure)
50-59:
  1. Aphasia (damage to the parts of the brain that control language)
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Confusional state
  4. Dysphagia (condition in which swallowing is difficult or painful)
  5. Hemiparesis (weakness on one side of the body)
  6. Pain in extremity
  7. Asthenia (weakness)
  8. Headache (pain in head)
  9. Affect lability (emotional incontinence)
  10. Drug ineffective
60+:
  1. Lactic acidosis (low ph in body tissues)
  2. Renal failure acute (rapid kidney dysfunction)
  3. Dehydration (dryness resulting from the removal of water)
  4. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  5. Dizziness
  6. Nausea (feeling of having an urge to vomit)
  7. Weight decreased
  8. Pyrexia (fever)
  9. Fatigue (feeling of tiredness)
  10. Decreased appetite

* Approximation only. Some reports may have incomplete information.

Do you take Irbesartan and Metformin?


You are not alone:




Related studies

Irbesartan

Irbesartan has active ingredients of irbesartan. It is often used in high blood pressure. (latest outcomes from Irbesartan 16,059 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 259,096 users)


Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Irbesartan and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Metformin and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Irbesartan and Metformin
a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

What would happen?

Predict new side effects and undetected conditions when you take Irbesartan and Metformin (51,920 reports studied)

FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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