Januvia and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Januvia and Hydrochlorothiazide. Common interactions include weight decreased among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people who take Januvia and Hydrochlorothiazide have. It is created by eHealthMe based on reports of 2,207 people who take Januvia and Hydrochlorothiazide from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
2,207 people who take Januvia and Hydrochlorothiazide together, and have interactions are studied.
What is Januvia?
Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 67,267 Januvia users for its effectiveness, alternative drugs and more.
What is Hydrochlorothiazide?
Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 160,958 Hydrochlorothiazide users for its effectiveness, alternative drugs and more.
Number of Januvia and Hydrochlorothiazide reports submitted per year:
Januvia and Hydrochlorothiazide drug interactions by gender *:
Januvia and Hydrochlorothiazide drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Januvia and Hydrochlorothiazide?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Liao KF, Lin CL, Lai SW, Chen WC, "Sitagliptin use and risk of acute pancreatitis in type 2 diabetes mellitus: a population-based case-control study in Taiwan", European journal of internal medicine, 2016 Jan .
- Belice T, Yuce S, Kizilkaya B, Kurt A, Cure E, "Noncardiac pulmonary edema induced by sitagliptin treatment", Journal of family medicine and primary care, 2014 Jan .
- Misgar, R. A., Bhat, J. A., Wani, A. I., & Bashir, M. I., "Sitagliptin induced splenic infarcts", Clinical Diabetology, 2014 Jan .
- Stricklin SM, Stoecker WV, Rader RK, Hood AF, Litt JZ, Schuman TP, "Persistent edematous-plaque photosensitivity observed with sitagliptin phosphate (Januvia?)", Dermatology online journal, 2012 Feb .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Januvia (67,267 reports)
- Hydrochlorothiazide (160,958 reports)
Common Januvia and Hydrochlorothiazide interactions:
- Fatigue (feeling of tiredness): 90 reports
- Weakness: 86 reports
- Dizziness: 64 reports
- Headache (pain in head): 62 reports
- Joint pain: 61 reports
- Pancreatitis (inflammation of pancreas): 54 reports
- Chronic kidney disease: 44 reports
- Chest pain: 38 reports
Browse all drug interactions of Januvia and Hydrochlorothiazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Januvia side effects:
- Drug ineffective: 3,347 reports
- Diarrhea: 3,114 reports
- Fatigue (feeling of tiredness): 2,735 reports
- Pancreatitis (inflammation of pancreas): 2,572 reports
- Weakness: 2,512 reports
- Headache (pain in head): 2,496 reports
Browse all side effects of Januvia:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Hydrochlorothiazide side effects:
- Fatigue (feeling of tiredness): 11,742 reports
- High blood pressure: 10,761 reports
- Drug ineffective: 10,097 reports
- Diarrhea: 9,391 reports
- Pain: 9,132 reports
- Dizziness: 8,727 reports
Browse all side effects of Hydrochlorothiazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Januvia interactions:
- Januvia and Metformin: 19,313 reports
- Januvia and Aspirin: 7,942 reports
- Januvia and Lisinopril: 5,713 reports
- Januvia and Lantus: 5,165 reports
- Januvia and Amlodipine: 4,440 reports
- Januvia and Glipizide: 4,245 reports
- Januvia and Furosemide: 4,034 reports
- Januvia and Lipitor: 3,773 reports
- Januvia and Simvastatin: 3,581 reports
- Januvia and Actos: 3,471 reports
Browse all interactions between Januvia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Hydrochlorothiazide interactions:
- Hydrochlorothiazide and Lisinopril: 25,815 reports
- Hydrochlorothiazide and Aspirin: 25,584 reports
- Hydrochlorothiazide and Amlodipine: 19,065 reports
- Hydrochlorothiazide and Metformin: 19,011 reports
- Hydrochlorothiazide and Prednisone: 14,909 reports
- Hydrochlorothiazide and Omeprazole: 14,757 reports
- Hydrochlorothiazide and Simvastatin: 12,918 reports
- Hydrochlorothiazide and Losartan: 12,907 reports
- Hydrochlorothiazide and Atenolol: 12,905 reports
- Hydrochlorothiazide and Gabapentin: 10,726 reports
Browse all interactions between Hydrochlorothiazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sitagliptin phosphate and hydrochlorothiazide (the active ingredients of Januvia and Hydrochlorothiazide, respectively), and Januvia and Hydrochlorothiazide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Januvia and Hydrochlorothiazide.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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