Keppra and Accutane drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Keppra and Accutane. Common interactions include pulmonary embolism among females and inflammatory bowel disease among males.
The phase IV clinical study analyzes what interactions people who take Keppra and Accutane have. It is created by eHealthMe based on reports of 36 people who take Keppra and Accutane from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
36 people who take Keppra and Accutane together, and have interactions are studied.
What is Keppra?
Keppra has active ingredients of levetiracetam. It is often used in epilepsy. eHealthMe is studying from 66,560 Keppra users for its effectiveness, alternative drugs and more.
What is Accutane?
Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 33,664 Accutane users for its effectiveness, alternative drugs and more.
Number of Keppra and Accutane reports submitted per year:

Common Keppra and Accutane drug interactions by gender *:
female:
- Pulmonary embolism
- Abdominal adhesions
- Anal fissure
- Bronchitis
- Colitis
- Convulsion
- Dizziness
- Head injury
- Headache
- Joint swelling
male:
- Inflammatory bowel disease
- Colitis ulcerative
- Arthralgia
- Arthritis
- Asthenia
- Blood glucose decreased
- Blood lactate dehydrogenase increased
- Blood uric acid decreased
- Bone marrow failure
- Cerebral disorder
Common Keppra and Accutane drug interactions by age *:
0-1:
n/a
2-9:
- Colitis ulcerative
- Depression
- Inflammatory bowel disease
- Abdominal adhesions
- Bronchitis
- Convulsion
- Crohn's disease
- Deep vein thrombosis
- Gastrointestinal injury
- Injury
10-19:
- Cerebral disorder
20-29:
- Oral discomfort
- Rash
- Rhinorrhoea
- Sinusitis
- Tremor
- Visual field defect
- Vomiting
- Weight decreased
- Xeroderma
- Emotional distress
30-39:
- Anal fissure
- Depression
- Inflammatory bowel disease
- Suicidal ideation
- Abortion spontaneous
- Clostridium difficile colitis
- Colitis ulcerative
- Crohn's disease
- Deep vein thrombosis
- Intestinal obstruction
40-49:
- Alopecia
- Arthralgia
- Blood cholesterol increased
- Blood triglycerides increased
- Cholelithiasis
- Colitis
- Colitis ulcerative
- Depression
- Dizziness
- Fall
50-59:
- Crohn's disease
- Death
- Inflammatory bowel disease
- Intestinal stenosis
- Glioblastoma multiforme
- Haematuria
- Hypertonic bladder
- Urge incontinence
60+:
- Inflammatory bowel disease
- Colitis ulcerative
- Blood triglycerides increased
- Cheilitis
- Cholestasis
- Crohn's disease
- Cytolytic hepatitis
- Dermatitis
- Hyperhidrosis
- Lip dry
Common conditions people have *:
- Brain Neoplasm Malignant (brain cancer tumour): 7 people, 19.44%
- Acne Cystic (skin problems that cause pimples): 3 people, 8.33%
- Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 2 people, 5.56%
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 5.56%
- Growth Hormone Deficiency: 2 people, 5.56%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 5.56%
- Birth Control: 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Keppra and Accutane?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Spengler DC, Montouris GD, Hohler AD, "Levetiracetam as a possible contributor to acute kidney injury", Clinical therapeutics, 2014 Aug .
- Almeida DM, Jean MR, Chystsiakova A, Monahan E, Oliveira SB, Monteiro IM, "Levetiracetam-associated acute pancreatitis in an adolescent with autism: a case report", Pancreas, 2013 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Keppra and Accutane interactions:
- Depression: 16 reports
- Headache (pain in head): 4 reports
Browse all drug interactions of Keppra and Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Keppra side effects:
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6,563 reports
- Fatigue (feeling of tiredness): 3,947 reports
- Drug ineffective: 3,428 reports
- Drowsiness: 2,702 reports
- Headache (pain in head): 2,524 reports
- Dizziness: 2,508 reports
- Weakness: 2,353 reports
Browse all side effects of Keppra:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane side effects:
- Depression: 9,826 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 9,190 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 7,519 reports
- Stress and anxiety: 5,193 reports
- Irritable bowel syndrome: 4,848 reports
Browse all side effects of Accutane:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Keppra interactions:
- Keppra and Lamictal: 5,003 reports
- Keppra and Vimpat: 4,661 reports
- Keppra and Aspirin: 3,354 reports
- Keppra and Topamax: 2,959 reports
- Keppra and Tegretol: 2,931 reports
- Keppra and Gabapentin: 2,475 reports
- Keppra and Clonazepam: 2,271 reports
- Keppra and Lamotrigine: 2,235 reports
- Keppra and Omeprazole: 2,220 reports
- Keppra and Depakote: 2,194 reports
Browse all interactions between Keppra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Accutane interactions:
- Accutane and Ortho tri-cyclen: 1,116 reports
- Accutane and Prednisone: 639 reports
- Accutane and Profen: 446 reports
- Accutane and Ibuprofen: 445 reports
- Accutane and Tylenol: 422 reports
- Accutane and Retin-a: 351 reports
- Accutane and Advil: 315 reports
- Accutane and Zoloft: 313 reports
- Accutane and Yasmin: 266 reports
- Accutane and Cleocin: 258 reports
Browse all interactions between Accutane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levetiracetam and isotretinoin (the active ingredients of Keppra and Accutane, respectively), and Keppra and Accutane (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Keppra and Accutane.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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