Kombiglyze xr and Fluoxetine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kombiglyze xr and Fluoxetine. Common interactions include cardiac failure among females and cardiac failure among males.

The phase IV clinical study analyzes what interactions people who take Kombiglyze xr and Fluoxetine have. It is created by eHealthMe based on reports of 19 people who take Kombiglyze xr and Fluoxetine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 18, 2023

19 people who take Kombiglyze xr and Fluoxetine together, and have interactions are studied.

What is Kombiglyze xr?

Kombiglyze xr has active ingredients of metformin hydrochloride; saxagliptin. It is often used in diabetes. eHealthMe is studying from 2,613 Kombiglyze xr users for its effectiveness, alternative drugs and more.

What is Fluoxetine?

Fluoxetine has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 85,788 Fluoxetine users for its effectiveness, alternative drugs and more.

Number of Kombiglyze xr and Fluoxetine reports submitted per year:

Common Kombiglyze Xr and Fluoxetine drug interactions by gender *:

female:

Cardiac failure
Cardiac failure congestive
Cardiovascular disorder
Coronary artery disease
Bundle branch block left
Cardiomegaly
Respiratory failure
Weight increased
Cardiac arrest
Cardiac valve disease

male:

Cardiac failure
Cardiac failure congestive
Pancreatic neuroendocrine tumour
Chronic obstructive pulmonary disease
Diabetic ketoacidosis
Left ventricular failure
Respiratory failure
Acute left ventricular failure
Acute myocardial infarction
Cardiovascular disorder

Common Kombiglyze Xr and Fluoxetine drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Diabetic ketoacidosis

30-39:

Abdominal pain upper
Blood glucose increased
Diarrhoea
Generalised oedema
Glycosylated haemoglobin increased
Inflammation
Nausea
Syncope
Weight increased

40-49:

Drug hypersensitivity
Paraesthesia oral

50-59:

Cardiac failure
Cardiac failure congestive
Respiratory failure
Left ventricular failure
Chronic obstructive pulmonary disease
Bundle branch block left
Cardiomegaly
Death
Decreased appetite
Dyspnoea

60+:

Cardiac failure
Cardiac failure congestive
Chronic left ventricular failure
Pancreatic neuroendocrine tumour
Pancreatitis
Pancreatitis acute
Renal failure
Cardiovascular disorder
Coronary artery disease
Myocardial infarction

Common conditions people have *:

Type 2 Diabetes: 12 people, 63.16%
Urinary Tract Infection: 1 person, 5.26%
Stress And Anxiety: 1 person, 5.26%
Neuropathy Peripheral (surface nerve damage): 1 person, 5.26%
Neuralgia (pain in one or more nerves): 1 person, 5.26%
Hypertriglyceridaemia (excess of triglycerides in the blood): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%
Cor Pulmonale Chronic (long lasting enlargement of the right ventricle of the heart): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Kombiglyze xr and Fluoxetine?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.