Labetalol hydrochloride and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Labetalol hydrochloride and Simvastatin. Common interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people who take Labetalol hydrochloride and Simvastatin have. It is created by eHealthMe based on reports of 86 people who take Labetalol hydrochloride and Simvastatin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Sep, 18, 2023

86 people who take Labetalol hydrochloride and Simvastatin together, and have interactions are studied.

What is Labetalol hydrochloride?

Labetalol hydrochloride has active ingredients of labetalol hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 2,155 Labetalol hydrochloride users for its effectiveness, alternative drugs and more.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 249,855 Simvastatin users for its effectiveness, alternative drugs and more.

Number of Labetalol hydrochloride and Simvastatin reports submitted per year:

Common Labetalol Hydrochloride and Simvastatin drug interactions by gender *:

female:

Headache
Vomiting
Cough
Diabetes mellitus
Fatigue
Arrhythmia
Arthralgia
Asthenia
Chronic kidney disease
Dizziness

male:

Chronic kidney disease
Back pain
Chest pain
Difficulty in walking
Disorientation
Erythema
Fatigue
Flushing
Headache
Myalgia

Common Labetalol Hydrochloride and Simvastatin drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Nephropathy
Renal injury

30-39:

n/a

40-49:

Anxiety
Blood glucose increased
Cardiomegaly
Chronic kidney disease
Diarrhoea
Dizziness
Dyspnoea
Electrocardiogram qt prolonged
Haemoglobin decreased
Headache

50-59:

Renal failure chronic
Skin exfoliation
Skin graft failure
Vomiting
Abdominal hernia
Asthenia
Back pain
Clostridium difficile colitis
Confusional state
Convulsion

60+:

Drug ineffective
Diabetes mellitus inadequate control
Abdominal discomfort
Cerebral haemorrhage
Dyspnoea
Cough
Dizziness
Drug hypersensitivity
Fatigue
Headache

Common conditions people have *:

Hyperkalemia (damage to or disease of the kidney): 16 people, 18.60%
Pain: 15 people, 17.44%
Diabetes: 12 people, 13.95%
Restless Leg Syndrome (a powerful urge to move your legs): 11 people, 12.79%
Osteoporosis (bones weak and more likely to break): 10 people, 11.63%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 10 people, 11.63%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 11.63%
Psoriasis (immune-mediated disease that affects the skin): 9 people, 10.47%
Oedema Peripheral (superficial swelling): 9 people, 10.47%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 10.47%

* Approximation only. Some reports may have incomplete information.

Do you take Labetalol hydrochloride and Simvastatin?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Labetalol hydrochloride (2,155 reports)
Simvastatin (249,855 reports)