Levaquin and Hydroxyurea drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Levaquin and Hydroxyurea. Common interactions include bacteraemia among females and fatigue among males.
The phase IV clinical study analyzes what interactions people who take Levaquin and Hydroxyurea have. It is created by eHealthMe based on reports of 96 people who take Levaquin and Hydroxyurea from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
96 people who take Levaquin and Hydroxyurea together, and have interactions are studied.
What is Levaquin?
Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 55,045 Levaquin users for its effectiveness, alternative drugs and more.
What is Hydroxyurea?
Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 13,918 Hydroxyurea users for its effectiveness, alternative drugs and more.
Number of Levaquin and Hydroxyurea reports submitted per year:

Common Levaquin and Hydroxyurea drug interactions by gender *:
female:
- Bacteraemia
- Chest pain
- Cytomegalovirus viraemia
- Leukaemia
- Lung infection
- Metabolic encephalopathy
- Pain in extremity
- Platelet count decreased
- Pruritus
- Rash maculo-papular
male:
- Fatigue
- Anaemia
- Pyrexia
- Acute myeloid leukaemia
- Hypotension
- Respiratory failure
- Blood creatinine increased
- Pancytopenia
- Urinary retention
- White blood cell count decreased
Common Levaquin and Hydroxyurea drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Respiratory syncytial virus infection
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Chest pain
- Clostridium difficile colitis
- Colonoscopy
- Death
- Epstein-barr virus infection
- Hypersensitivity
- Mycobacterial infection
20-29:
- Dyspnoea
- Unresponsive to stimuli
30-39:
- Acute myeloid leukaemia
- Cellulitis
- Death
- Fatigue
- Pancytopenia
- Stomatitis
40-49:
- Concomitant disease progression
- Diarrhoea
- Erythema
- Feeling hot
- Gastroenteritis
- Haemolysis
- Haemosiderosis
- Jaundice
- Klebsiella infection
- Lobar pneumonia
50-59:
- Febrile neutropenia
- Mucosal inflammation
- Hypotension
- Respiratory failure
- Cytomegalovirus viraemia
- Metabolic encephalopathy
- Vaginal haemorrhage
- Acute myeloid leukaemia
- Atelectasis
- Cerebral infarction
60+:
- Anaemia
- Fatigue
- Acute myeloid leukaemia
- Hypoxia
- Blood creatinine increased
- Blood pressure decreased
- Chills
- Lung infection
- Oxygen saturation decreased
- Pulmonary mass
Common conditions people have *:
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 40 people, 41.67%
- High Blood Pressure: 16 people, 16.67%
- Pain: 14 people, 14.58%
- Nausea (feeling of having an urge to vomit): 13 people, 13.54%
- Primary Myelofibrosis (primary disorder of the bone marrow): 11 people, 11.46%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 11 people, 11.46%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.42%
- Stress And Anxiety: 6 people, 6.25%
- Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 6 people, 6.25%
- Itching: 6 people, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Levaquin and Hydroxyurea?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Bhuvan KC, ALrasheedy AA, Ibrahim MI, "A case report from Nepalese community pharmacy on levofloxacin induced severe abdominal pain", Saudi Pharmaceutical Journal, 2013 Jul .
- MITTAL V, ARCHANA D, GUPTA A, SRIVASTAV U, CHANDRA V, SAXENA A, AGRAWAL P, "Aphasia: a Rarest Complication with a Well Known Drug Levofloxacin", Medical Science, 2013 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Levaquin (55,045 reports)
- Hydroxyurea (13,918 reports)
Browse all drug interactions of Levaquin and Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levaquin side effects:
- Pain: 5,268 reports
- Joint pain: 4,266 reports
- Stress and anxiety: 3,943 reports
- Weakness: 3,848 reports
- Breathing difficulty: 3,741 reports
- Fatigue (feeling of tiredness): 3,545 reports
Browse all side effects of Levaquin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Hydroxyurea side effects:
- Fatigue (feeling of tiredness): 1,423 reports
- Diarrhea: 1,237 reports
- Headache (pain in head): 953 reports
- Thrombocytopenia (decrease of platelets in blood): 892 reports
- Weakness: 794 reports
- Fever: 786 reports
- Pain: 754 reports
Browse all side effects of Hydroxyurea:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Levaquin interactions:
- Levaquin and Prednisone: 6,696 reports
- Levaquin and Aspirin: 5,090 reports
- Levaquin and Protonix: 4,008 reports
- Levaquin and Nexium: 3,829 reports
- Levaquin and Lasix: 3,677 reports
- Levaquin and Lisinopril: 3,504 reports
- Levaquin and Prilosec: 3,470 reports
- Levaquin and Tylenol: 3,179 reports
- Levaquin and Albuterol: 3,164 reports
- Levaquin and Cipro: 3,058 reports
Browse all interactions between Levaquin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Hydroxyurea interactions:
- Hydroxyurea and Jakafi: 2,801 reports
- Hydroxyurea and Aspirin: 2,287 reports
- Hydroxyurea and Lopurin: 1,671 reports
- Hydroxyurea and Omeprazole: 922 reports
- Hydroxyurea and Furosemide: 834 reports
- Hydroxyurea and Amlodipine: 777 reports
- Hydroxyurea and Lisinopril: 762 reports
- Hydroxyurea and Vitamin d: 705 reports
- Hydroxyurea and Prednisone: 687 reports
- Hydroxyurea and Folic acid: 681 reports
Browse all interactions between Hydroxyurea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on levofloxacin and hydroxyurea (the active ingredients of Levaquin and Hydroxyurea, respectively), and Levaquin and Hydroxyurea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Levaquin and Hydroxyurea.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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