Lidocaine and Skelaxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lidocaine and Skelaxin. Common interactions include dyspnoea among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people who take Lidocaine and Skelaxin have. It is created by eHealthMe based on reports of 98 people who take Lidocaine and Skelaxin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
98 people who take Lidocaine and Skelaxin together, and have interactions are studied.
What is Lidocaine?
Lidocaine has active ingredients of lidocaine. It is often used in pain. eHealthMe is studying from 15,233 Lidocaine users for its effectiveness, alternative drugs and more.
What is Skelaxin?
Skelaxin has active ingredients of metaxalone. It is often used in back pain. eHealthMe is studying from 9,567 Skelaxin users for its effectiveness, alternative drugs and more.
Number of Lidocaine and Skelaxin reports submitted per year:

Common Lidocaine and Skelaxin drug interactions by gender *:
female:
- Dyspnoea
- Osteonecrosis of jaw
- Rib fracture
- Vision blurred
- Gingival bleeding
- Sinusitis
- Intervertebral disc degeneration
- Metastases to bone
- Mitral valve incompetence
- Osteoarthritis
male:
- Arthralgia
- Headache
- Pain in extremity
- Sinusitis
- Somnolence
- Tooth disorder
- Weight decreased
- Angioedema
- Anorectal discomfort
- Asthma
Common Lidocaine and Skelaxin drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Anxiety
- Deep vein thrombosis
- Emotional distress
- General physical health deterioration
- Injury
- Pulmonary embolism
- Pulmonary infarction
- Viral infection
20-29:
- Maculopathy
30-39:
- Mucosal inflammation
- Nausea
- Palmar-plantar erythrodysaesthesia syndrome
- Pneumonia
- Rash
40-49:
- Arthralgia
- Bone disorder
- Depression
- Lung infiltration
- Musculoskeletal pain
- Pain in extremity
- Cough
- Osteonecrosis of jaw
- Rib fracture
- Chronic obstructive pulmonary disease
50-59:
- Diarrhoea
- Diplopia
- Dysphagia
- Haemorrhoids
- Hypoaesthesia
- Hypotension
- Intervertebral disc protrusion
- Limb injury
- Multiple sclerosis
- Muscle twitching
60+:
- Weight decreased
- Dysphagia
- Therapeutic agent toxicity
- Alopecia
- Anaemia
- Asthenia
- Atrioventricular block
- Balance disorder
- Bundle branch block right
- Carotid artery aneurysm
Common conditions people have *:
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 15 people, 15.31%
- Nerve Block (the interruption of signals travelling along a nerve): 8 people, 8.16%
- Anaesthesia: 8 people, 8.16%
- Headache (pain in head): 7 people, 7.14%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 7.14%
- Sleep Disorder: 5 people, 5.10%
- Neck Pain: 5 people, 5.10%
- Muscle Spasms (muscle contraction): 5 people, 5.10%
- Dry Eyes (lack of adequate tears): 5 people, 5.10%
* Approximation only. Some reports may have incomplete information.
Do you take Lidocaine and Skelaxin?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Lidocaine and Skelaxin interactions:
- Pain: 37 reports
- Breathing difficulty: 19 reports
Browse all drug interactions of Lidocaine and Skelaxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lidocaine side effects:
- Pain: 1,948 reports
- Stress and anxiety: 1,406 reports
- Fatigue (feeling of tiredness): 1,048 reports
- Hypotension (abnormally low blood pressure): 957 reports
- Headache (pain in head): 948 reports
- Acute kidney failure: 944 reports
Browse all side effects of Lidocaine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Skelaxin side effects:
- Pain: 1,202 reports
- Stress and anxiety: 898 reports
- Fatigue (feeling of tiredness): 793 reports
- Headache (pain in head): 743 reports
- Back pain: 705 reports
- Depression: 684 reports
- Breathing difficulty: 682 reports
- High blood pressure: 631 reports
Browse all side effects of Skelaxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lidocaine interactions:
- Lidocaine and Acetaminophen: 2,840 reports
- Lidocaine and Hydramine: 2,028 reports
- Lidocaine and Heparin: 1,960 reports
- Lidocaine and Epinephrine: 1,875 reports
- Lidocaine and Aspirin: 1,822 reports
- Lidocaine and Fentanyl: 1,775 reports
- Lidocaine and Morphine: 1,567 reports
- Lidocaine and Gabapentin: 1,382 reports
- Lidocaine and Propofol: 1,367 reports
- Lidocaine and Prednisone: 1,344 reports
Browse all interactions between Lidocaine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Skelaxin interactions:
- Skelaxin and Nexium: 1,146 reports
- Skelaxin and Celebrex: 1,136 reports
- Skelaxin and Lyrica: 1,054 reports
- Skelaxin and Neurontin: 992 reports
- Skelaxin and Aspirin: 932 reports
- Skelaxin and Ambien: 877 reports
- Skelaxin and Cymbalta: 827 reports
- Skelaxin and Tramadol: 819 reports
- Skelaxin and Vioxx: 796 reports
- Skelaxin and Lipitor: 755 reports
Browse all interactions between Skelaxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lidocaine and metaxalone (the active ingredients of Lidocaine and Skelaxin, respectively), and Lidocaine and Skelaxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Lidocaine and Skelaxin.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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