Lonsurf and Pentasa drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported only by a few people who take Lonsurf and Pentasa together.
The phase IV clinical study analyzes what interactions people who take Lonsurf and Pentasa have. It is created by eHealthMe based on reports of 2 people who take the same drugs from the FDA, and is updated regularly.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
2 people who take Lonsurf and Pentasa together, and have interactions are studied.
What is Lonsurf?
Lonsurf has active ingredients of tipiracil hydrochloride; trifluridine. eHealthMe is studying from 8,062 Lonsurf users for its effectiveness, alternative drugs and more.
What is Pentasa?
Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 19,553 Pentasa users for its effectiveness, alternative drugs and more.
Number of Lonsurf and Pentasa reports submitted per year:

Common Lonsurf and Pentasa drug interactions by gender *:
female:
- Deep vein thrombosis
male:
- Alopecia
- Dyspepsia
Common Lonsurf and Pentasa drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Deep vein thrombosis
60+:
n/a
* Approximation only. Some reports may have incomplete information.
Do you take Lonsurf and Pentasa?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Jacobsson H, Eriksen J, Karlén P, "Mesalazine-induced renal calculi", The American journal of case reports, 2015 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Lonsurf and Pentasa:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lonsurf side effects:
- Death: 2,259 reports
- Fatigue (feeling of tiredness): 1,035 reports
- Diarrhea: 755 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 501 reports
- Nausea and vomiting: 487 reports
- Weakness: 394 reports
Browse all side effects of Lonsurf:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Pentasa side effects:
- Drug ineffective: 1,790 reports
- Crohn's disease (condition that causes inflammation of the gastrointestinal tract): 1,746 reports
- Diarrhea: 1,715 reports
- Fatigue (feeling of tiredness): 1,263 reports
- Abdominal pain: 1,175 reports
- Ulcerative colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1,125 reports
- Fever: 1,106 reports
- Headache (pain in head): 1,000 reports
- Joint pain: 987 reports
Browse all side effects of Pentasa:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lonsurf interactions:
- Lonsurf and Amlodipine: 507 reports
- Lonsurf and Gabapentin: 502 reports
- Lonsurf and Ondansetron: 488 reports
- Lonsurf and Zofran: 463 reports
- Lonsurf and Lisinopril: 453 reports
- Lonsurf and Oxycodone: 445 reports
- Lonsurf and Omeprazole: 355 reports
- Lonsurf and Metformin: 321 reports
- Lonsurf and Morphine: 314 reports
- Lonsurf and Furosemide: 264 reports
Browse all interactions between Lonsurf and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Pentasa interactions:
- Pentasa and Humira: 5,579 reports
- Pentasa and Prednisone: 3,767 reports
- Pentasa and Remicade: 3,499 reports
- Pentasa and Imuran: 1,615 reports
- Pentasa and Azathioprine: 1,083 reports
- Pentasa and Vitamin d: 1,073 reports
- Pentasa and Omeprazole: 1,011 reports
- Pentasa and Pantoprazole: 961 reports
- Pentasa and Methotrexate: 878 reports
- Pentasa and Prednisolone: 871 reports
Browse all interactions between Pentasa and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on tipiracil hydrochloride; trifluridine and mesalamine (the active ingredients of Lonsurf and Pentasa, respectively), and Lonsurf and Pentasa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Lonsurf and Pentasa.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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