Lorcet-hd and Pristiq drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among 7 people who take Lorcet-hd and Pristiq. Common interactions include disorientation among females, and sudden onset of sleep among males.

The phase IV clinical study analyzes what interactions people who take Lorcet-hd and Pristiq have. It is created by eHealthMe based on reports from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions.

On Sep, 25, 2023

7 people who take Lorcet-hd and Pristiq together, and have interactions are studied.

What is Lorcet-hd?

Lorcet-hd has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain. Currently, eHealthMe is studying from 2,221 Lorcet-hd users.

What is Pristiq?

Pristiq has active ingredients of desvenlafaxine succinate. It is used in depression. Currently, eHealthMe is studying from 19,471 Pristiq users.

Number of Lorcet-hd and Pristiq reports submitted per year:

Lorcet-hd and Pristiq drug interactions.

Common Lorcet-Hd and Pristiq drug interactions by gender *:


  1. Disorientation
  2. Diarrhoea
  3. Dyspnoea
  4. Eructation
  5. Eye infection
  6. Fatigue
  7. Fluid retention
  8. Hyperhidrosis
  9. Nervousness
  10. Ocular hyperaemia


  1. Sudden onset of sleep

Common Lorcet-Hd and Pristiq drug interactions by age *:










  1. Aggression
  2. Anger
  3. Nervousness
  4. Social avoidant behaviour


  1. Arthralgia
  2. Diarrhoea
  3. Disorientation
  4. Dizziness
  5. Dyspnoea
  6. Eructation
  7. Fatigue
  8. Fluid retention
  9. Hyperhidrosis
  10. Palpitations


  1. Drug effect decreased
  2. Irritability
  3. Obsessive thoughts
  4. Somnolence


  1. Disorientation
  2. Dizziness
  3. Eye infection
  4. Ocular hyperaemia
  5. Vision blurred

* Approximation only. Some reports may have incomplete information.

Do you take Lorcet-hd and Pristiq?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Common Lorcet-hd side effects:

Browse all side effects of Lorcet-hd:

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Common Pristiq side effects:

Browse all side effects of Pristiq:

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Common Lorcet-hd interactions:

Browse all interactions between Lorcet-hd and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Pristiq interactions:

Browse all interactions between Pristiq and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; hydrocodone bitartrate and desvenlafaxine succinate (the active ingredients of Lorcet-hd and Pristiq, respectively), and Lorcet-hd and Pristiq (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Lorcet-hd and Pristiq.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 700+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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