Losartan and Pravastatin sodium drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Losartan and Pravastatin sodium together. This study is created by eHealthMe based on reports of 629 people who take Losartan and Pravastatin sodium from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on losartan potassium and pravastatin sodium (the active ingredients of Losartan and Pravastatin sodium, respectively), and Losartan and Pravastatin sodium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Losartan?

Losartan has active ingredients of losartan potassium. It is often used in high blood pressure. (latest outcomes from Losartan 74,370 users)

What is Pravastatin sodium?

Pravastatin sodium has active ingredients of pravastatin sodium. It is often used in high blood cholesterol. (latest outcomes from Pravastatin sodium 16,024 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 12, 2019

629 people who take Losartan, Pravastatin sodium are studied.


Number of reports submitted per year:

Losartan and Pravastatin sodium drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Aptyalism (deficiency or absence of saliva)
  2. Arthralgia (joint pain)
  3. Dry mouth
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  5. Stupor (lack of critical cognitive function and level of consciousness)
  6. Abdominal pain upper
  7. Acute myocardial infarction (acute heart attack)
  8. Asthenia (weakness)
  9. Atelectasis (partial or complete collapse of the lung)
  10. Back pain
1 - 6 months:
  1. Insomnia (sleeplessness)
  2. Abnormal faeces (abnormal stool)
  3. Arthralgia (joint pain)
  4. Bradyphrenia (neurological term referring to the slowness of thought common to many disorders of the brain)
  5. Diarrhoea
  6. Eye swelling
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Intraventricular haemorrhage (intraventricular bleeding)
  9. Liver disorder (liver diseases)
  10. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
6 - 12 months:
  1. Accidental overdose
  2. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  4. Depression
  5. Dysphagia (condition in which swallowing is difficult or painful)
  6. Dyspnoea (difficult or laboured respiration)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Blood creatine phosphokinase increased
  9. Drug eruption (adverse drug reaction of the skin)
  10. International normalised ratio increased
1 - 2 years:
  1. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  2. Blood pressure decreased
  3. Dizziness
  4. Irritability
  5. Blood creatinine increased
  6. Blood iron increased
  7. Blood pressure systolic increased
  8. Blood urea increased
  9. Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
  10. Haemoglobin decreased
2 - 5 years:
  1. Irritability
  2. Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
  3. Blood iron increased
  4. Blood pressure systolic increased
  5. Bone marrow depression (decreased ability or inability of the bone marrow to produce blood cells)
  6. Drug eruption (adverse drug reaction of the skin)
  7. Eschar (dead tissue that falls off (sheds) from healthy skin)
  8. Pulmonary haemorrhage (acute bleeding from the lung)
  9. Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands)
  10. Serum ferritin increased
5 - 10 years:
  1. Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
  2. Muscle disorder (muscle disease)
  3. Plasma cell myeloma (cancer that begins in plasma cells)
  4. Pre-existing condition improved
  5. Pulmonary haemorrhage (acute bleeding from the lung)
  6. Therapeutic response unexpected
10+ years:

n/a

not specified:
  1. Pneumonia
  2. Diarrhoea
  3. Asthenia (weakness)
  4. Fall
  5. Vomiting
  6. Drug ineffective
  7. Blood glucose increased
  8. Hypotension (abnormally low blood pressure)
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Pain

Most common drug interactions by gender *:

female:
  1. Drug ineffective
  2. Dizziness
  3. Dyspnoea (difficult or laboured respiration)
  4. Vomiting
  5. Gait disturbance
  6. Renal failure (kidney dysfunction)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Asthma
  9. Hypotension (abnormally low blood pressure)
  10. Muscle spasms (muscle contraction)
male:
  1. Fatigue (feeling of tiredness)
  2. Asthenia (weakness)
  3. Drug ineffective
  4. Nausea (feeling of having an urge to vomit)
  5. Rash
  6. Cardiac failure congestive
  7. Fall
  8. Hypotension (abnormally low blood pressure)
  9. Back pain
  10. Vomiting

Most common drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:
  1. Lymphangioma (tumour of lymph nodes)
  2. Calcinosis (calcium deposits in any soft tissue)
  3. Drug effect decreased
  4. Fluid retention (an abnormal accumulation of fluid in the blood)
  5. General physical health deterioration (weak health status)
  6. Hepatic adenoma (benign liver tumour)
  7. Hepatic mass
  8. Hepatic neoplasm (liver tumour)
  9. Liver disorder (liver diseases)
  10. Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
30-39:
  1. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  2. Asthma
  3. Blood pressure fluctuation
  4. Depression
  5. Fibromyalgia (a long-term condition which causes pain all over the body)
  6. Gait disturbance
  7. Intervertebral disc degeneration (spinal disc degeneration)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  10. Nausea (feeling of having an urge to vomit)
40-49:
  1. Headache (pain in head)
  2. Blood pressure decreased
  3. Dizziness postural
  4. Fatigue (feeling of tiredness)
  5. Feeling hot
  6. Heart rate decreased
  7. Muscle spasms (muscle contraction)
  8. Pain in extremity
  9. Palpitations (feelings or sensations that your heart is pounding or racing)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)
50-59:
  1. Dysstasia (difficulty in standing)
  2. Hypotension (abnormally low blood pressure)
  3. Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
  4. Myalgia (muscle pain)
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  6. Asthenia (weakness)
  7. Dehydration (dryness resulting from the removal of water)
  8. Nausea (feeling of having an urge to vomit)
  9. Cough
  10. Nightmare (unpleasant dream)
60+:
  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Pain
  4. Abdominal pain upper
  5. Hypotension (abnormally low blood pressure)
  6. Abdominal distension
  7. Blood glucose increased
  8. Back pain
  9. Drug ineffective
  10. Weight decreased

* Approximation only. Some reports may have incomplete information.

Do you take Losartan and Pravastatin sodium?


You are not alone:




Related publications that referenced our studies


Results from eHealthMe (non-FDA) reports of taking Losartan and Pravastatin sodium together

Drug effectiveness (drug is found to be effective) over time *:
Losartan:
  • < 1 month: 0.0% (0 of 3 people)
  • 1 - 6 months: 33% (4 of 12 people)
  • 6 - 12 months: 0.0% (0 of 5 people)
  • 1 - 2 years: 16% (2 of 12 people)
  • 2 - 5 years: 14% (1 of 7 people)
  • 5 - 10 years: 36% (4 of 11 people)
  • 10+ years: 50% (1 of 2 people)
  • not specified: 0.0% (0 of 0 people)
Pravastatin sodium:
  • < 1 month: 0.0% (0 of 0 people)
  • 1 - 6 months: 16% (1 of 6 people)
  • 6 - 12 months: 20% (1 of 5 people)
  • 1 - 2 years: 37% (3 of 8 people)
  • 2 - 5 years: 33% (5 of 15 people)
  • 5 - 10 years: 46% (6 of 13 people)
  • 10+ years: 33% (1 of 3 people)
  • not specified: 0.0% (0 of 0 people)
Drug effectiveness (drug is found to be effective) by gender *:
Losartan:
  • female: 22% (5 of 22 people)
  • male: 23% (7 of 30 people)
Pravastatin sodium:
  • female: 35% (7 of 20 people)
  • male: 33% (10 of 30 people)
Drug effectiveness (drug is found to be effective) by age *:
Losartan:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 0.0% (0 of 4 people)
  • 40-49: 0.0% (0 of 5 people)
  • 50-59: 36.0% (4 of 11 people)
  • 60+: 25.0% (8 of 32 people)
Pravastatin sodium:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 25.0% (1 of 4 people)
  • 40-49: 20.0% (1 of 5 people)
  • 50-59: 27.0% (3 of 11 people)
  • 60+: 40.0% (12 of 30 people)
Race of the people *:
  • African American, Non-Hispanic: 1.67 %
  • American Indian/Alaska Native: 0.56 %
  • Asian: 0.56 %
  • Hispanic: 1.11 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 96.11 %

* Approximation only.


Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Losartan and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Pravastatin sodium and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Losartan and Pravastatin sodium
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Losartan and Pravastatin sodium (24,719 reports studied)



FDA reports used in this study


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