Metformin and Atorvastatin calcium drug interactions - from FDA reports


Drug interactions are reported among people who take Metformin and Atorvastatin calcium together. This study is created by eHealthMe based on reports of 3,518 people who take Metformin and Atorvastatin calcium from FDA, and is updated regularly.

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On Jan, 18, 2019

3,518 people who take Metformin, Atorvastatin calcium are studied.


Number of reports submitted per year:

Metformin and Atorvastatin calcium drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Pyrexia (fever)
  2. Diarrhoea
  3. Bacterial infection
  4. C-reactive protein increased
  5. Drug eruption (adverse drug reaction of the skin)
  6. Gastric ulcer (stomach ulcer)
  7. Lymphadenopathy mediastinal (an enlargement of the lymph nodes in the part of the chest that separates the lungs)
  8. Dizziness
  9. Fall
  10. Fracture
1 - 6 months:
  1. Leukopenia (less number of white blood cells in blood)
  2. Pruritus (severe itching of the skin)
  3. Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
  4. Psoriasis (immune-mediated disease that affects the skin)
  5. Septic shock (shock due to blood infection)
  6. Superinfection
  7. Dyspnoea (difficult or laboured respiration)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Myalgia (muscle pain)
  10. Dehydration (dryness resulting from the removal of water)
6 - 12 months:
  1. Vomiting
  2. Respiratory tract infection
  3. Vertigo
  4. Alveolitis fibrosing (idiopathic pulmonary fibrosis)
  5. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  6. Flushing (the warm, red condition of human skin)
  7. Hypokalaemia (low potassium)
  8. Myalgia (muscle pain)
  9. Nausea (feeling of having an urge to vomit)
  10. Pneumonia
1 - 2 years:
  1. Tremor (trembling or shaking movements in one or more parts of your body)
  2. Weight decreased
  3. Constipation
  4. Dystonia (abnormal muscle tone)
  5. Nausea (feeling of having an urge to vomit)
  6. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  7. Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)
  8. Renal failure acute (rapid kidney dysfunction)
  9. Urinary retention (the inability to completely or partially empty the bladder)
  10. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
2 - 5 years:
  1. Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
  2. Blood creatine phosphokinase increased
  3. Chronic kidney disease
  4. Lactic acidosis (low ph in body tissues)
  5. Muscle spasms (muscle contraction)
  6. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  7. Blood bicarbonate decreased
  8. Cardiac arrest
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea
5 - 10 years:
  1. Weight decreased
  2. Constipation
  3. Dystonia (abnormal muscle tone)
  4. Nausea (feeling of having an urge to vomit)
  5. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  6. Tremor (trembling or shaking movements in one or more parts of your body)
  7. Reflux oesophagitis (an oesophageal mucosal injury that occurs of gastric contents into the oesophagus)
  8. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  9. Urinary retention (the inability to completely or partially empty the bladder)
  10. Muscle spasms (muscle contraction)
10+ years:
  1. Blood creatine phosphokinase increased
  2. Cardiac arrest
  3. Vomiting
  4. Myalgia (muscle pain)
  5. Diarrhoea
  6. Haemorrhage intracranial (bleeding within the skull)
  7. Hypoxia (low oxygen in tissues)
  8. Lactic acidosis (low ph in body tissues)
  9. Rectal haemorrhage (bleeding from anus)
  10. Renal failure acute (rapid kidney dysfunction)
not specified:
  1. Diarrhoea
  2. Dyspnoea (difficult or laboured respiration)
  3. Fatigue (feeling of tiredness)
  4. Nausea (feeling of having an urge to vomit)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Vomiting
  7. Dizziness
  8. Asthenia (weakness)
  9. Blood glucose increased
  10. Pain

Most common drug interactions by gender *:

female:
  1. Anaemia (lack of blood)
  2. Drug ineffective
  3. Weight decreased
  4. Arthralgia (joint pain)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pain in extremity
  7. Urinary tract infection
  8. Pneumonia
  9. Fall
  10. Headache (pain in head)
male:
  1. Dyspnoea (difficult or laboured respiration)
  2. Fatigue (feeling of tiredness)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  5. Arthralgia (joint pain)
  6. Pneumonia
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Fall
  9. Vomiting
  10. Anaemia (lack of blood)

Most common drug interactions by age *:

0-1:
  1. Lactic acidosis (low ph in body tissues)
  2. Renal failure acute (rapid kidney dysfunction)
2-9:
  1. Depression
  2. Dizziness
  3. Headache (pain in head)
10-19:
  1. Abdominal discomfort
  2. Abortion spontaneous (naturally occurring miscarriage)
  3. Drug ineffective
  4. Pain
  5. Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
  6. Acidosis (build-up of carbon dioxide in the blood)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Arthralgia (joint pain)
  10. Back pain
20-29:
  1. Blood glucose increased
  2. Myalgia (muscle pain)
  3. Gastric disorder (disease of stomach)
  4. High density lipoprotein decreased
  5. Hypoglycaemia (deficiency of glucose in the bloodstream)
  6. Low density lipoprotein increased (cholesterol increased in blood)
  7. Abdominal pain
  8. Abortion induced (medically referred abortion)
  9. Arthralgia (joint pain)
  10. Asthma
30-39:
  1. Glycosylated haemoglobin increased
  2. General physical health deterioration (weak health status)
  3. Hyperglycaemia (high blood sugar)
  4. Hypotension (abnormally low blood pressure)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Respiratory failure (inadequate gas exchange by the respiratory system)
  7. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  8. Arthralgia (joint pain)
  9. Bradycardia (abnormally slow heart action)
  10. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
40-49:
  1. Pancreatitis (inflammation of pancreas)
  2. Diabetes mellitus inadequate control
  3. Urinary tract infection
  4. Obesity (a medical condition in which excess body fat)
  5. Renal failure acute (rapid kidney dysfunction)
  6. Glycosylated haemoglobin increased
  7. Nausea (feeling of having an urge to vomit)
  8. Weight decreased
  9. Pneumonia
  10. Blood glucose increased
50-59:
  1. Arthralgia (joint pain)
  2. Dizziness
  3. Asthenia (weakness)
  4. Muscle spasms (muscle contraction)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Dyspnoea (difficult or laboured respiration)
  7. Pain in extremity
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Headache (pain in head)
  10. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
60+:
  1. Diarrhoea
  2. Renal failure acute (rapid kidney dysfunction)
  3. Fall
  4. Weight decreased
  5. Blood glucose increased
  6. Pain
  7. Confusional state
  8. Hypotension (abnormally low blood pressure)
  9. Arthralgia (joint pain)
  10. Dehydration (dryness resulting from the removal of water)

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and Atorvastatin calcium?


You are not alone:




Related studies

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 259,096 users)

Atorvastatin calcium

Atorvastatin calcium has active ingredients of atorvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Atorvastatin calcium 34,006 users)


Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Metformin and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Atorvastatin calcium and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Metformin and Atorvastatin calcium
a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

What would happen?

Predict new side effects and undetected conditions when you take Metformin and Atorvastatin calcium

FDA reports used in this study



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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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