Methotrexate and Plaquenil drug interactions - from FDA reports


Drug interactions are reported among people who take Methotrexate and Plaquenil together. This review analyzes the effectiveness and drug interactions between Methotrexate and Plaquenil. It is created by eHealthMe based on reports of 11,985 people who take the same drugs from FDA , and is updated regularly.



On Jul, 15, 2018

11,985 people who take Methotrexate, Plaquenil are studied.


Number of reports submitted per year:

Methotrexate and Plaquenil drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Fatigue (feeling of tiredness)
  2. Arthralgia (joint pain)
  3. Joint swelling
  4. Pain
  5. Nausea (feeling of having an urge to vomit)
1 - 6 months:
  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Abdominal discomfort
  4. Fatigue (feeling of tiredness)
  5. Pain
6 - 12 months:
  1. Drug ineffective
  2. Fatigue (feeling of tiredness)
  3. Nausea (feeling of having an urge to vomit)
  4. Peripheral swelling
  5. Nasopharyngitis (inflammation of the nasopharynx)
1 - 2 years:
  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Joint swelling
  4. Pain
  5. Drug intolerance (drug sensitivity)
2 - 5 years:
  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Pain
  4. Fatigue (feeling of tiredness)
  5. Drug intolerance (drug sensitivity)
5 - 10 years:
  1. Drug effect decreased
  2. Drug intolerance (drug sensitivity)
  3. Headache (pain in head)
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Pain
not specified:
  1. Drug ineffective
  2. Arthralgia (joint pain)
  3. Pain
  4. Nausea (feeling of having an urge to vomit)
  5. Fatigue (feeling of tiredness)

Most common drug interactions by gender *:

male:
  1. Drug ineffective
  2. Arthralgia (joint pain)
  3. Headache (pain in head)
  4. Dyspnoea (difficult or laboured respiration)
  5. Rash

Most common drug interactions by age *:

0-1:
  1. Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
  2. Pyrexia (fever)
  3. Congenital pyelocaliectasis (birth defect of upper urinary tract obstruction)
  4. Congenital spinal cord anomaly (abnormal spinal cord by birth)
  5. Viral upper respiratory tract infection
2-9:
  1. Renal failure acute (rapid kidney dysfunction)
  2. Back pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypertension (high blood pressure)
  5. Pruritus (severe itching of the skin)
10-19:
  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Injection site pain
  4. Pain
  5. Dyspnoea (difficult or laboured respiration)
20-29:
  1. Drug ineffective
  2. Nausea (feeling of having an urge to vomit)
  3. Arthralgia (joint pain)
  4. Headache (pain in head)
  5. Nasopharyngitis (inflammation of the nasopharynx)
30-39:
  1. Drug ineffective
  2. Fatigue (feeling of tiredness)
  3. Headache (pain in head)
  4. Nausea (feeling of having an urge to vomit)
  5. Nasopharyngitis (inflammation of the nasopharynx)
40-49:
  1. Drug ineffective
  2. Pain
  3. Arthralgia (joint pain)
  4. Fatigue (feeling of tiredness)
  5. Joint swelling
50-59:
  1. Drug ineffective
  2. Pain
  3. Arthralgia (joint pain)
  4. Nausea (feeling of having an urge to vomit)
  5. Fatigue (feeling of tiredness)

* Approximation only. Some reports may have incomplete information.

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Related studies

Methotrexate

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 234,889 users)

Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. (latest outcomes from Plaquenil 33,468 users)


Interactions between Methotrexate and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Plaquenil and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Methotrexate and Plaquenil
a b c d e f g h i j k l m n o p q r s t u v w x y z

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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