Methotrexate and Plaquenil drug interactions - from FDA reports
Drug interactions are reported among people who take Methotrexate and Plaquenil together. This study is created by eHealthMe based on reports of 17,735 people who take Methotrexate and Plaquenil from FDA, and is updated regularly.
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17,735 people who take Methotrexate, Plaquenil are studied.
Number of reports submitted per year:
Most common drug interactions over time *:
< 1 month:
1 - 6 months:
6 - 12 months:
1 - 2 years:
2 - 5 years:
5 - 10 years:
Most common drug interactions by gender *:
- Drug ineffective
- Joint swelling
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Treatment failure
- Pulmonary embolism (blockage of the main artery of the lung)
- Drug effect decreased
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Dyspnoea (difficult or laboured respiration)
Most common drug interactions by age *:
- Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
- Pyrexia (fever)
- Congenital pyelocaliectasis (birth defect of upper urinary tract obstruction)
- Congenital spinal cord anomaly (abnormal spinal cord by birth)
- Viral upper respiratory tract infection
- Asthenia (weakness)
- Atrial septal defect (an abnormal opening between the left and right atria of the heart)
- Bladder diverticulum (pouch like projection in the bladder, by birth or acquired)
- Cardiac murmur (an heart sound in valve abnormality)
- Cardiac septal defect (heart valve defect by birth)
- Renal failure acute (rapid kidney dysfunction)
- Back pain
- Dyspnoea (difficult or laboured respiration)
- Hypertension (high blood pressure)
- Pruritus (severe itching of the skin)
- Renal failure chronic (long lasting kidney dysfunction)
- Colonic pseudo-obstruction (severe impairment in the ability of the intestines to push food through)
- Pneumatosis intestinalis (air or gas in an intestine)
- Abdominal distension
* Approximation only. Some reports may have incomplete information.
FDA reports used in this study
- Want to find out more about the FDA reports used in the study? You can request them from FDA.
Do you take Methotrexate and Plaquenil?
You are not alone:
Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 307,853 users)
Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in systemic lupus erythematosus. (latest outcomes from Plaquenil 45,283 users)
Browse by gender and age
Interactions between Methotrexate and drugs from A to Za b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Plaquenil and drugs from A to Za b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Methotrexate and Plaquenila b c d e f g h i j k l m n o p q r s t u v w x y z
Related publications that referenced our studies
- Henien M, Carey B, Hullah E, Sproat C, Patel V, "methotrexate-associated osteonecrosis of the jaw: A report of two cases", Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 2017 Dec .
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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.
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