Miralax and Phenytoin drug interactions - a phase IV clinical study of FDA data


Drug interactions are reported among people who take Miralax and Phenytoin. Common interactions include communication disorder among females and convulsion among males.

The phase IV clinical study analyzes what interactions people who take Miralax and Phenytoin have. It is created by eHealthMe based on reports of 35 people who take Miralax and Phenytoin from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Nov, 24, 2022

35 people who take Miralax and Phenytoin together, and have interactions are studied.

What is Miralax?

Miralax has active ingredients of polyethylene glycol 3350. It is often used in constipation. eHealthMe is studying from 72,714 Miralax users for its effectiveness, alternative drugs and more.

What is Phenytoin?

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. eHealthMe is studying from 13,397 Phenytoin users for its effectiveness, alternative drugs and more.

Number of Miralax and Phenytoin reports submitted per year:

Miralax and Phenytoin drug interactions.

Common Miralax and Phenytoin drug interactions by gender *:


  1. Communication disorder
  2. Compression fracture
  3. Conjunctival haemorrhage
  4. Death
  5. Dental plaque
  6. Device related infection
  7. Dizziness
  8. Drug abuse
  9. Drug ineffective
  10. Drug level below therapeutic


  1. Convulsion
  2. Dyspnoea
  3. Erythema
  4. Headache
  5. Hypotension
  6. Lethargy
  7. Malaise
  8. Pancreatitis acute
  9. Paraesthesia
  10. Pharyngeal oedema

Common Miralax and Phenytoin drug interactions by age *:




  1. Clostridium difficile colitis
  2. Convulsion
  3. Klebsiella infection
  4. Lobar pneumonia
  5. Metapneumovirus infection
  6. Pyrexia
  7. Rash erythematous
  8. Rash papular
  9. Rash pruritic
  10. Respiratory distress


  1. Convulsion
  2. Pulmonary embolism
  3. Agitation
  4. Akathisia
  5. Drug level below therapeutic
  6. Eye movement disorder
  7. Gingival hyperplasia
  8. Injury
  9. Mood altered
  10. Movement disorder


  1. Convulsion
  2. Granulocytopenia


  1. Convulsion
  2. Drug abuse
  3. Drug ineffective


  1. Bronchiolitis
  2. Convulsion
  3. Drug effect decreased
  4. Drug level decreased
  5. Dyspnoea
  6. Injury
  7. Lung infiltration
  8. Pain
  9. Pulmonary embolism


  1. Pleural effusion
  2. Sinus headache
  3. Vomiting
  4. Death
  5. Faecal incontinence
  6. Hyperglycaemia
  7. Nausea


  1. Convulsion
  2. Nausea
  3. Headache
  4. Hypotension
  5. Lethargy
  6. Malaise
  7. Pancreatitis acute
  8. Paraesthesia
  9. Pharyngeal oedema
  10. Photosensitivity reaction

Common conditions people have *:

  1. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 9 people, 25.71%
  2. Pain: 7 people, 20.00%
  3. Stress And Anxiety: 5 people, 14.29%
  4. Diarrhea: 4 people, 11.43%
  5. Nausea (feeling of having an urge to vomit): 3 people, 8.57%
  6. Multiple Myeloma (cancer of the plasma cells): 3 people, 8.57%
  7. Mucosal Inflammation (infection of mucous membrane): 3 people, 8.57%
  8. Malignant Melanoma (skin cancer rises from melancytes): 3 people, 8.57%
  9. Insomnia (sleeplessness): 3 people, 8.57%
  10. Diabetes: 3 people, 8.57%

* Approximation only. Some reports may have incomplete information.

Do you take Miralax and Phenytoin?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related publications that referenced our studies

  • Wandalkar P, Daswani BR, Pandit PT, Ghongane BB, "A case of Phenytoin toxicity", INTERNATIONAL JOURNAL OF ADVANCES IN PHARMACY, BIOLOGY AND CHEMISTRY, 2014 Jan .

Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Miralax and Phenytoin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Miralax interactions:

Browse all interactions between Miralax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Phenytoin interactions:

Browse all interactions between Phenytoin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on polyethylene glycol 3350 and phenytoin (the active ingredients of Miralax and Phenytoin, respectively), and Miralax and Phenytoin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Miralax and Phenytoin.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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