Namenda and Lunesta drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Namenda and Lunesta. Common interactions include meningitis viral among females and fall among males.
The phase IV clinical study analyzes what interactions people who take Namenda and Lunesta have. It is created by eHealthMe based on reports of 82 people who take Namenda and Lunesta from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
82 people who take Namenda and Lunesta together, and have interactions are studied.
What is Namenda?
Namenda has active ingredients of memantine hydrochloride. It is often used in dementia. eHealthMe is studying from 13,744 Namenda users for its effectiveness, alternative drugs and more.
What is Lunesta?
Lunesta has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 25,595 Lunesta users for its effectiveness, alternative drugs and more.
Number of Namenda and Lunesta reports submitted per year:

Common Namenda and Lunesta drug interactions by gender *:
female:
- Meningitis viral
- Type 2 diabetes mellitus
- Urinary tract infection
- Asthenia
- Cardiac failure congestive
- Constipation
- Depression
- Diarrhoea
- Diastolic dysfunction
- Dysstasia
male:
- Fall
- Hyperhidrosis
- Aggression
- Blood pressure increased
- Confusional state
- Dry mouth
- Hallucination
- Heart rate increased
- Bipolar disorder
- Blood insulin increased
Common Namenda and Lunesta drug interactions by age *:
0-1:
- Blood cholesterol increased
- Blood triglycerides increased
- Hyperprolactinaemia
- Leiomyoma
- Obesity
- Osteoarthritis
- Patellofemoral pain syndrome
- Stress fracture
- Type 2 diabetes mellitus
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Acanthosis
- Arthralgia
- Asthma
- Blood cholesterol increased
- Blood triglycerides increased
- Chest pain
- Constipation
- Convulsion
- Dyspnoea
- Fracture
40-49:
n/a
50-59:
- Renal impairment
- Respiratory arrest
- Upper respiratory tract infection
- Aphasia
- Asthenia
- Cardiac disorder
- Cerebrovascular accident
- Cold sweat
- Drug administration error
- Drug effect delayed
60+:
- Confusional state
- Catatonia
- Abnormal behaviour
- Aggression
- Disorientation
- Drug ineffective
- Encephalitis
- General physical health deterioration
- Hip fracture
- Meningitis viral
Common conditions people have *:
- Depression: 11 people, 13.41%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 10.98%
- Parkinson's Disease: 8 people, 9.76%
- Pain: 8 people, 9.76%
- Stress And Anxiety: 7 people, 8.54%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 7.32%
- High Blood Pressure: 6 people, 7.32%
- High Blood Cholesterol: 6 people, 7.32%
- Type 2 Diabetes: 5 people, 6.10%
- Psychotic Disorder: 5 people, 6.10%
* Approximation only. Some reports may have incomplete information.
Do you take Namenda and Lunesta?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Namenda and Lunesta:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Namenda side effects:
- Dizziness: 974 reports
- Fatigue (feeling of tiredness): 916 reports
- Drowsiness: 844 reports
- Weakness: 767 reports
- Death: 612 reports
- Drug ineffective: 600 reports
Browse all side effects of Namenda:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lunesta side effects:
- Drug ineffective: 4,839 reports
- Insomnia (sleeplessness): 4,208 reports
- Taste - impaired: 4,104 reports
- Headache (pain in head): 1,293 reports
- Fatigue (feeling of tiredness): 1,257 reports
- Stress and anxiety: 1,227 reports
- Pain: 1,066 reports
Browse all side effects of Lunesta:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Namenda interactions:
- Namenda and Aricept: 3,363 reports
- Namenda and Aspirin: 2,155 reports
- Namenda and Lisinopril: 970 reports
- Namenda and Synthroid: 950 reports
- Namenda and Seroquel: 878 reports
- Namenda and Lipitor: 867 reports
- Namenda and Vitamin d: 836 reports
- Namenda and Omeprazole: 823 reports
- Namenda and Donepezil: 817 reports
- Namenda and Nuplazid: 794 reports
Browse all interactions between Namenda and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Lunesta interactions:
- Lunesta and Ambien: 2,291 reports
- Lunesta and Cymbalta: 1,857 reports
- Lunesta and Aspirin: 1,767 reports
- Lunesta and Nexium: 1,714 reports
- Lunesta and Xanax: 1,479 reports
- Lunesta and Xyrem: 1,469 reports
- Lunesta and Lyrica: 1,426 reports
- Lunesta and Synthroid: 1,371 reports
- Lunesta and Gabapentin: 1,270 reports
- Lunesta and Lisinopril: 1,268 reports
Browse all interactions between Lunesta and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on memantine hydrochloride and eszopiclone (the active ingredients of Namenda and Lunesta, respectively), and Namenda and Lunesta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Namenda and Lunesta.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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