Nexavar and Xylocaine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nexavar and Xylocaine. Common interactions include abdominal discomfort among females and hypertension among males.
The phase IV clinical study analyzes what interactions people who take Nexavar and Xylocaine have. It is created by eHealthMe based on reports of 9 people who take Nexavar and Xylocaine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
9 people who take Nexavar and Xylocaine together, and have interactions are studied.
What is Nexavar?
Nexavar has active ingredients of sorafenib tosylate. It is often used in hepatocellular carcinoma. eHealthMe is studying from 22,624 Nexavar users for its effectiveness, alternative drugs and more.
What is Xylocaine?
Xylocaine has active ingredients of lidocaine hydrochloride. eHealthMe is studying from 5,700 Xylocaine users for its effectiveness, alternative drugs and more.
Number of Nexavar and Xylocaine reports submitted per year:

Common Nexavar and Xylocaine drug interactions by gender *:
female:
- Abdominal discomfort
- Alopecia
- Anaemia
- Back pain
- Erythema
- Headache
- Hypoaesthesia
- Neuralgia
- Pain in extremity
- Palmar-plantar erythrodysaesthesia syndrome
male:
- Hypertension
- Pleural effusion
- Hypoalbuminaemia
- Renal failure
- Respiratory failure
- Anaemia
- Acidosis
- Convulsion
- Face oedema
- Hypoglycaemia
Common Nexavar and Xylocaine drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Abdominal discomfort
- Alopecia
- Anaemia
- Back pain
- Erythema
- Headache
- Hypoaesthesia
- Neuralgia
- Pain in extremity
- Palmar-plantar erythrodysaesthesia syndrome
60+:
- Hypertension
- Pleural effusion
- Hypoalbuminaemia
- Renal failure
- Respiratory failure
- Anaemia
- Acidosis
- Convulsion
- Face oedema
- Hypoglycaemia
* Approximation only. Some reports may have incomplete information.
Do you take Nexavar and Xylocaine?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Nexavar and Xylocaine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Nexavar side effects:
- Diarrhea: 3,767 reports
- Rashes (redness): 2,997 reports
- High blood pressure: 2,517 reports
- Fatigue (feeling of tiredness): 2,170 reports
- Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat): 1,840 reports
- Hepatocellular carcinoma (liver cancer): 1,817 reports
- Death: 1,553 reports
Browse all side effects of Nexavar:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Xylocaine side effects:
- Drug ineffective: 836 reports
- Hypotension (abnormally low blood pressure): 414 reports
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 263 reports
- Pain: 261 reports
- High blood pressure: 219 reports
Browse all side effects of Xylocaine:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Nexavar interactions:
- Nexavar and Lasix: 971 reports
- Nexavar and Urso 250: 758 reports
- Nexavar and Aldactone: 619 reports
- Nexavar and Aspirin: 612 reports
- Nexavar and Oxycontin: 551 reports
- Nexavar and Norvasc: 509 reports
- Nexavar and Omeprazole: 496 reports
- Nexavar and Amlodipine: 467 reports
- Nexavar and Furosemide: 429 reports
- Nexavar and Stivarga: 406 reports
Browse all interactions between Nexavar and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Xylocaine interactions:
- Xylocaine and Fentanyl: 408 reports
- Xylocaine and Lasix: 370 reports
- Xylocaine and Heparin: 320 reports
- Xylocaine and Morphine: 313 reports
- Xylocaine and Diprivan: 302 reports
- Xylocaine and Marcaine: 214 reports
- Xylocaine and Propofol: 207 reports
- Xylocaine and Aspirin: 200 reports
- Xylocaine and Atarax: 196 reports
- Xylocaine and Dexamethasone: 165 reports
Browse all interactions between Xylocaine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on sorafenib tosylate and lidocaine hydrochloride (the active ingredients of Nexavar and Xylocaine, respectively), and Nexavar and Xylocaine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Nexavar and Xylocaine.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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