Nyquil and Zantac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Nyquil and Zantac. Common interactions include chronic kidney disease among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people who take Nyquil and Zantac have. It is created by eHealthMe based on reports of 33 people who take Nyquil and Zantac from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
33 people who take Nyquil and Zantac together, and have interactions are studied.
What is Nyquil?
Nyquil has active ingredients of acetaminophen / dextromethorphan / doxylamine / pseudoephedrine. It is often used in cold symptoms. eHealthMe is studying from 2,050 Nyquil users for its effectiveness, alternative drugs and more.
What is Zantac?
Zantac has active ingredients of ranitidine hydrochloride. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 433,180 Zantac users for its effectiveness, alternative drugs and more.
Number of Nyquil and Zantac reports submitted per year:

Common Nyquil and Zantac drug interactions by gender *:
female:
- Chronic kidney disease
- Device related infection
- Sleep apnoea syndrome
- Weight decreased
- Asthma exercise induced
- Familial mediterranean fever
- Haematuria
- Hysterectomy
- Nausea
- Oropharyngeal pain
male:
- Chronic kidney disease
- Aphonia
- Anxiety
- Bone disorder
- Chronic obstructive pulmonary disease
- Depression
- Fall
- Humerus fracture
- Hyperparathyroidism secondary
- Influenza
Common Nyquil and Zantac drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Androgen deficiency
- Ankle fracture
- Anxiety
- Bone disorder
- Chronic kidney disease
- Chronic obstructive pulmonary disease
- Depression
- Fall
- Hospitalisation
- Humerus fracture
30-39:
- Familial mediterranean fever
- Hysterectomy
- Abnormal behaviour
- Agoraphobia
- Arthralgia
- Back pain
- Bankruptcy
- Binge eating
- Blunted affect
- Compulsive sexual behaviour
40-49:
- Chronic kidney disease
- Menorrhagia
- Sinusitis
50-59:
- Oropharyngeal pain
- Productive cough
- Renal failure
- Anxiety
- Chronic kidney disease
- Aphonia
- Diarrhoea
- Dysphonia
- Heart rate irregular
- Helicobacter infection
60+:
- Chronic kidney disease
- Influenza
- Spinal compression fracture
- Yersinia infection
Common conditions people have *:
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 12 people, 36.36%
- High Blood Pressure: 7 people, 21.21%
- Nasopharyngitis (inflammation of the nasopharynx): 7 people, 21.21%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 15.15%
- Stress And Anxiety: 4 people, 12.12%
- Depression: 4 people, 12.12%
- Pain: 4 people, 12.12%
- Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 4 people, 12.12%
- Infection: 4 people, 12.12%
- Headache (pain in head): 4 people, 12.12%
* Approximation only. Some reports may have incomplete information.
Do you take Nyquil and Zantac?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Browse all drug interactions of Nyquil and Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Nyquil side effects:
- Fatigue (feeling of tiredness): 108 reports
Browse all side effects of Nyquil:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Zantac side effects:
- Prostate cancer: 42,886 reports
- Colon cancer: 38,438 reports
- Renal cell carcinoma (a kidney cancer): 31,691 reports
- Breast cancer: 31,011 reports
- Bladder cancer: 28,922 reports
- Gastric cancer (stomach cancer): 14,090 reports
- Pancreatic carcinoma (pancreatic cancer): 11,333 reports
Browse all side effects of Zantac:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Nyquil interactions:
- Nyquil and Dayquil: 292 reports
- Nyquil and Tylenol: 230 reports
- Nyquil and Xyrem: 208 reports
- Nyquil and Aspirin: 185 reports
- Nyquil and Vitamin d: 180 reports
- Nyquil and Profen: 174 reports
- Nyquil and Ibu: 173 reports
- Nyquil and Mucinex: 142 reports
- Nyquil and Benadryl: 126 reports
- Nyquil and Omeprazole: 114 reports
Browse all interactions between Nyquil and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Zantac interactions:
- Zantac and Ranitidine: 87,401 reports
- Zantac and Nexium: 10,488 reports
- Zantac and Aspirin: 9,568 reports
- Zantac and Prilosec: 9,529 reports
- Zantac and Prednisone: 7,957 reports
- Zantac and Prevacid: 7,861 reports
- Zantac and Protonix: 7,120 reports
- Zantac and Omeprazole: 6,292 reports
- Zantac and Lisinopril: 6,268 reports
- Zantac and Tylenol: 5,750 reports
Browse all interactions between Zantac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen / dextromethorphan / doxylamine / pseudoephedrine and ranitidine hydrochloride (the active ingredients of Nyquil and Zantac, respectively), and Nyquil and Zantac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Nyquil and Zantac.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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