Oxycontin and Zyprexa drug interactions - from FDA reports


Drug interactions are reported among people who take Oxycontin and Zyprexa together. This study is created by eHealthMe based on reports of 483 people who take Oxycontin and Zyprexa from FDA, and is updated regularly.

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On Jan, 11, 2019

483 people who take Oxycontin, Zyprexa are studied.


Number of reports submitted per year:

Oxycontin and Zyprexa drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Decreased appetite
  2. Leukoencephalopathy (disease of the white matter in the brain)
  3. Multi-organ failure (multisystem organ failure)
  4. Anoxic encephalopathy (brain damage due to lack of oxygen)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Completed suicide (act of taking one's own life)
  7. Gastrointestinal inflammation (inflammation of stomach and intestine)
  8. Overdose
  9. Gastritis (inflammation of stomach)
  10. Liver function test abnormal
1 - 6 months:
  1. Suicidal ideation
  2. Dyspnoea (difficult or laboured respiration)
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  4. Hallucination, auditory (perceiving sounds without auditory stimulus)
  5. Headache (pain in head)
  6. Nausea (feeling of having an urge to vomit)
  7. Arthralgia (joint pain)
  8. Dehydration (dryness resulting from the removal of water)
  9. Drug dependence
  10. Chest pain
6 - 12 months:
  1. Drug dependence
  2. Chest pain
  3. Dizziness
  4. Drug ineffective
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Panic attack
  8. Suicidal ideation
  9. Anxiety
  10. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
1 - 2 years:
  1. Constipation
  2. Drug dependence
  3. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  4. Nightmare (unpleasant dream)
  5. Oedema peripheral (superficial swelling)
  6. Weight decreased
  7. Chest pain
  8. Drug ineffective
  9. Headache (pain in head)
  10. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
2 - 5 years:
  1. Blood cholesterol increased
  2. Blood glucose decreased
  3. Blood pressure abnormal
  4. Blood pressure diastolic increased
  5. Blood triglycerides increased
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Cardiomegaly (increased size of heart than normal)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Chronic obstructive airways disease exacerbated
  10. Coordination abnormal (abnormal movement)
5 - 10 years:
  1. Fall
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Gait disturbance
  4. Glaucoma (increased fluid pressure in the eye with vision loss)
  5. Hepatic steatosis (fatty liver disease)
  6. Intervertebral disc disorder (spinal disc disorder)
  7. Loss of consciousness
  8. Neuropathy peripheral (surface nerve damage)
  9. Pain in extremity
  10. Pancreatitis (inflammation of pancreas)
10+ years:

n/a

not specified:
  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Fatigue (feeling of tiredness)
  5. Arthralgia (joint pain)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Chest pain
  8. Osteonecrosis of jaw (death of bone of jaw)
  9. Dehydration (dryness resulting from the removal of water)
  10. Diarrhoea

Most common drug interactions by gender *:

female:
  1. Spinal osteoarthritis (joint cartilage loss in spine)
  2. Arthralgia (joint pain)
  3. Osteomyelitis (infection of bone)
  4. Diarrhoea
  5. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  6. Pain in jaw
  7. Weight increased
  8. Injury
  9. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  10. Pyrexia (fever)
male:
  1. Drug dependence
  2. Suicidal ideation
  3. Drug ineffective
  4. Pain in extremity
  5. Dehydration (dryness resulting from the removal of water)
  6. Vomiting
  7. Agitation (state of anxiety or nervous excitement)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

Most common drug interactions by age *:

0-1:
  1. Cardiac arrest
  2. Hypertension (high blood pressure)
  3. Pulmonary embolism (blockage of the main artery of the lung)
  4. Unresponsive to stimuli
2-9:
  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Chest tightness
  6. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  7. Drug dependence
  8. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  9. Dyspnoea (difficult or laboured respiration)
  10. Emotional distress
10-19:
  1. Anoxic encephalopathy (brain damage due to lack of oxygen)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Completed suicide (act of taking one's own life)
  4. Multi-organ failure (multisystem organ failure)
  5. Overdose
  6. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Accidental overdose
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Coagulopathy (blood's ability to clot is impaired)
20-29:
  1. Anxiety
  2. Cardiac failure
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Dehydration (dryness resulting from the removal of water)
  5. Myocarditis (inflammation of heart muscle myocardium)
  6. Pulmonary embolism (blockage of the main artery of the lung)
  7. Splenomegaly (enlargement of spleen)
  8. Accidental overdose
  9. Agitation (state of anxiety or nervous excitement)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
30-39:
  1. Suicidal ideation
  2. Dyspnoea (difficult or laboured respiration)
  3. Anxiety
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Arthralgia (joint pain)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Memory impairment
  9. Pyrexia (fever)
  10. Dehydration (dryness resulting from the removal of water)
40-49:
  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Insomnia (sleeplessness)
  5. Suicidal ideation
  6. Constipation
  7. Anxiety
  8. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  9. Oedema peripheral (superficial swelling)
  10. Drug dependence
50-59:
  1. Fatigue (feeling of tiredness)
  2. Decreased interest
  3. Headache (pain in head)
  4. Osteonecrosis of jaw (death of bone of jaw)
  5. Decreased appetite
  6. Spinal osteoarthritis (joint cartilage loss in spine)
  7. Actinomycosis (infection that causes sores, or abscesses)
  8. Diarrhoea
  9. Osteomyelitis (infection of bone)
  10. Pain in jaw
60+:
  1. Pneumonia
  2. Decreased appetite
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Cellulitis (infection under the skin)
  5. Confusional state
  6. Dehydration (dryness resulting from the removal of water)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fall
  9. Oedema peripheral (superficial swelling)
  10. Osteonecrosis of jaw (death of bone of jaw)

* Approximation only. Some reports may have incomplete information.

FDA reports used in this study



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Browse by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Oxycontin and drugs from A to Z
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Interactions between Zyprexa and drugs from A to Z
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Browse all drug interactions of Oxycontin and Zyprexa
a b c d e f g h i j k l m n o p q r s t u v w x y z

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What would happen?

Predict new side effects and undetected conditions when you take Oxycontin and Zyprexa (30,174 reports studied)

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