Oxycontin and Zyprexa drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Oxycontin and Zyprexa together. This study is created by eHealthMe based on reports of 483 people who take Oxycontin and Zyprexa from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on oxycodone hydrochloride and olanzapine (the active ingredients of Oxycontin and Zyprexa, respectively), and Oxycontin and Zyprexa (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Oxycontin?

Oxycontin has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycontin 93,862 users)

What is Zyprexa?

Zyprexa has active ingredients of olanzapine. It is often used in bipolar disorder. (latest outcomes from Zyprexa 57,205 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 26, 2019

483 people who take Oxycontin, Zyprexa are studied.


Number of reports submitted per year:

Oxycontin and Zyprexa drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Decreased appetite
  2. Leukoencephalopathy (disease of the white matter in the brain)
  3. Multi-organ failure (multisystem organ failure)
  4. Anoxic encephalopathy (brain damage due to lack of oxygen)
  5. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  6. Completed suicide (act of taking one's own life)
  7. Gastrointestinal inflammation (inflammation of stomach and intestine)
  8. Overdose
  9. Gastritis (inflammation of stomach)
  10. Somnolence (a state of near-sleep, a strong desire for sleep)
1 - 6 months:
  1. Suicidal ideation
  2. Dyspnoea (difficult or laboured respiration)
  3. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  4. Drug abuser
  5. Hallucination, auditory (perceiving sounds without auditory stimulus)
  6. Headache (pain in head)
  7. Nausea (feeling of having an urge to vomit)
  8. Arthralgia (joint pain)
  9. Dehydration (dryness resulting from the removal of water)
  10. Drug dependence
6 - 12 months:
  1. Drug dependence
  2. Chest pain
  3. Dizziness
  4. Drug ineffective
  5. Dyspnoea (difficult or laboured respiration)
  6. Headache (pain in head)
  7. Panic attack
  8. Suicidal ideation
  9. Vomiting
  10. Anxiety
1 - 2 years:
  1. Constipation
  2. Drug dependence
  3. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  4. Nightmare (unpleasant dream)
  5. Oedema peripheral (superficial swelling)
  6. Weight decreased
  7. Chest pain
  8. Drug ineffective
  9. Headache (pain in head)
  10. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
2 - 5 years:
  1. Bedridden
  2. Blood calcium decreased
  3. Blood cholesterol increased
  4. Blood glucose decreased
  5. Blood pressure diastolic increased
  6. Blood triglycerides increased
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Cardiomegaly (increased size of heart than normal)
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Chronic obstructive airways disease
5 - 10 years:
  1. Fall
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Gait disturbance
  4. Glaucoma (increased fluid pressure in the eye with vision loss)
  5. Hepatic steatosis (fatty liver disease)
  6. Intervertebral disc disorder (spinal disc disorder)
  7. Loss of consciousness
  8. Neuropathy peripheral (surface nerve damage)
  9. Pain in extremity
  10. Pancreatitis (inflammation of pancreas)
10+ years:

n/a

not specified:
  1. Anxiety
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Fatigue (feeling of tiredness)
  5. Arthralgia (joint pain)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Chest pain
  8. Diarrhoea
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Dehydration (dryness resulting from the removal of water)

Most common drug interactions by gender *:

female:
  1. Headache (pain in head)
  2. Spinal osteoarthritis (joint cartilage loss in spine)
  3. Arthralgia (joint pain)
  4. Osteomyelitis (infection of bone)
  5. Diarrhoea
  6. Pneumonia
  7. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  8. Pain in jaw
  9. Weight increased
  10. Injury
male:
  1. Anxiety
  2. Drug dependence
  3. Dizziness
  4. Drug ineffective
  5. Pain in extremity
  6. Dehydration (dryness resulting from the removal of water)
  7. Agitation (state of anxiety or nervous excitement)
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Drug abuser

Most common drug interactions by age *:

0-1:
  1. Cardiac arrest
  2. Hypertension (high blood pressure)
  3. Pulmonary embolism (blockage of the main artery of the lung)
  4. Unresponsive to stimuli
2-9:
  1. Angina pectoris (chest pain due to ischemia of the heart muscle)
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
  4. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  5. Chest tightness
  6. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  7. Disease recurrence
  8. Drug abuser
  9. Drug dependence
  10. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
10-19:
  1. Anoxic encephalopathy (brain damage due to lack of oxygen)
  2. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  3. Completed suicide (act of taking one's own life)
  4. Multi-organ failure (multisystem organ failure)
  5. Overdose
  6. Brain oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain)
  7. Encephalopathy (functioning of the brain is affected by some agent or condition)
  8. Accidental overdose
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Coagulopathy (blood's ability to clot is impaired)
20-29:
  1. Anxiety
  2. Cardiac failure
  3. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  4. Dehydration (dryness resulting from the removal of water)
  5. Myocarditis (inflammation of heart muscle myocardium)
  6. Condition
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Splenomegaly (enlargement of spleen)
  9. Accidental overdose
  10. Agitation (state of anxiety or nervous excitement)
30-39:
  1. Dyspnoea (difficult or laboured respiration)
  2. Anxiety
  3. Suicidal ideation
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Arthralgia (joint pain)
  6. Headache (pain in head)
  7. Vomiting
  8. Fatigue (feeling of tiredness)
  9. Diarrhoea
  10. Memory impairment
40-49:
  1. Chest pain
  2. Dyspnoea (difficult or laboured respiration)
  3. Headache (pain in head)
  4. Pneumonia
  5. Insomnia (sleeplessness)
  6. Suicidal ideation
  7. Constipation
  8. Anxiety
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Oedema peripheral (superficial swelling)
50-59:
  1. Oedema peripheral (superficial swelling)
  2. Fatigue (feeling of tiredness)
  3. Decreased interest
  4. Headache (pain in head)
  5. Osteonecrosis of jaw (death of bone of jaw)
  6. Decreased appetite
  7. Spinal osteoarthritis (joint cartilage loss in spine)
  8. Urinary tract infection
  9. Actinomycosis (infection that causes sores, or abscesses)
  10. Diarrhoea
60+:
  1. Pneumonia
  2. Decreased appetite
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Cellulitis (infection under the skin)
  5. Confusional state
  6. Dehydration (dryness resulting from the removal of water)
  7. Dyspnoea (difficult or laboured respiration)
  8. Fall
  9. Oedema peripheral (superficial swelling)
  10. Osteonecrosis of jaw (death of bone of jaw)

* Approximation only. Some reports may have incomplete information.


Do you take Oxycontin and Zyprexa?


You are not alone, use our "Ginger Health" app to:

  • connect with people like you who take Oxycontin and Zyprexa
  • use your healthcare experience to help people like you, and be rewarded



Related publications that referenced our studies


Results from eHealthMe (non-FDA) reports of taking Oxycontin and Zyprexa together

Drug effectiveness (drug is found to be effective) over time *:
Oxycontin:
  • < 1 month: 100% (1 of 1 people)
  • 1 - 6 months: 0.0% (0 of 2 people)
  • 6 - 12 months: 0.0% (0 of 0 people)
  • 1 - 2 years: 0.0% (0 of 0 people)
  • 2 - 5 years: 0.0% (0 of 1 people)
  • 5 - 10 years: 0.0% (0 of 0 people)
  • 10+ years: 0.0% (0 of 0 people)
  • not specified: 0.0% (0 of 0 people)
Zyprexa:
  • < 1 month: 0.0% (0 of 1 people)
  • 1 - 6 months: 0.0% (0 of 1 people)
  • 6 - 12 months: 0.0% (0 of 0 people)
  • 1 - 2 years: 0.0% (0 of 0 people)
  • 2 - 5 years: 0.0% (0 of 0 people)
  • 5 - 10 years: 0.0% (0 of 0 people)
  • 10+ years: 0.0% (0 of 0 people)
  • not specified: 0.0% (0 of 0 people)
Drug effectiveness (drug is found to be effective) by gender *:
Oxycontin:
  • female: 0.0% (0 of 3 people)
  • male: 100% (1 of 1 people)
Zyprexa:
  • female: 0.0% (0 of 2 people)
  • male: 0.0% (0 of 0 people)
Drug effectiveness (drug is found to be effective) by age *:
Oxycontin:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 50.0% (1 of 2 people)
  • 30-39: 0.0% (0 of 0 people)
  • 40-49: 0.0% (0 of 0 people)
  • 50-59: 0.0% (0 of 0 people)
  • 60+: 0.0% (0 of 2 people)
Zyprexa:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 0.0% (0 of 0 people)
  • 40-49: 0.0% (0 of 0 people)
  • 50-59: 0.0% (0 of 0 people)
  • 60+: 0.0% (0 of 2 people)
Race of the people *:
  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 100 %

* Approximation only.


Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Oxycontin and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Zyprexa and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Oxycontin and Zyprexa
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Oxycontin and Zyprexa (30,174 reports studied)



FDA reports used in this study


Recent updates

Recent general studies
Recent personal studies


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.