Paracetamol and Xylocaine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Paracetamol and Xylocaine. Common interactions include febrile neutropenia among females and cytokine release syndrome among males.

The phase IV clinical study analyzes what interactions people who take Paracetamol and Xylocaine have. It is created by eHealthMe based on reports of 45 people who take Paracetamol and Xylocaine from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.



On Sep, 25, 2022

45 people who take Paracetamol and Xylocaine together, and have interactions are studied.


What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 114,957 Paracetamol users for its effectiveness, alternative drugs and more.

What is Xylocaine?

Xylocaine has active ingredients of lidocaine hydrochloride. eHealthMe is studying from 5,700 Xylocaine users for its effectiveness, alternative drugs and more.

Number of Paracetamol and Xylocaine reports submitted per year:

Paracetamol and Xylocaine drug interactions.

Common Paracetamol and Xylocaine drug interactions by gender *:

female:

  1. Febrile neutropenia
  2. Diarrhoea
  3. Mucosal inflammation
  4. Abdominal pain upper
  5. Decreased appetite
  6. Dehydration
  7. Eating disorder
  8. Hypokalaemia
  9. Nausea
  10. Takayasu's arteritis

male:

  1. Cytokine release syndrome
  2. Enterococcal sepsis
  3. Skin exfoliation
  4. Wound infection
  5. Angioedema
  6. Asthenia
  7. Blister
  8. Bone marrow failure
  9. Chest pain
  10. Cholecystitis acute

Common Paracetamol and Xylocaine drug interactions by age *:

0-1:

n/a

2-9:

  1. Febrile neutropenia
  2. Mucosal inflammation
  3. Neutropenia

10-19:

  1. Cytokine release syndrome
  2. Enterococcal sepsis
  3. Metabolic acidosis
  4. Bone marrow failure
  5. Ischaemic stroke
  6. Thrombocytopenia

20-29:

  1. Pulmonary embolism
  2. Diabetic retinopathy
  3. Hypoglycaemia

30-39:

n/a

40-49:

  1. Takayasu's arteritis
  2. Cholecystitis acute

50-59:

  1. Hypertension
  2. Paraneoplastic syndrome
  3. Febrile bone marrow aplasia
  4. Infection
  5. Alopecia
  6. Angioedema
  7. Anxiety
  8. Chest pain
  9. Confusional state
  10. Duodenal perforation

60+:

  1. Diarrhoea
  2. Febrile neutropenia
  3. Nausea
  4. Sepsis
  5. Fluid retention
  6. General physical health deterioration
  7. Pemphigoid
  8. Cardio-respiratory arrest
  9. Hypotension
  10. Incision site infection

Common conditions people have *:

  1. Nausea (feeling of having an urge to vomit): 19 people, 42.22%
  2. Constipation: 11 people, 24.44%
  3. High Blood Pressure: 10 people, 22.22%
  4. Stress And Anxiety: 8 people, 17.78%
  5. Fever: 8 people, 17.78%
  6. Insomnia (sleeplessness): 6 people, 13.33%
  7. Febrile Neutropenia (fever with reduced white blood cells): 6 people, 13.33%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.33%
  9. Diarrhea: 5 people, 11.11%
  10. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Paracetamol and Xylocaine?

Personalize this study to your gender and age

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.



Related studies

Alternative drugs to, pros and cons of the 2 drugs:

Browse all drug interactions of Paracetamol and Xylocaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Paracetamol interactions:

Browse all interactions between Paracetamol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common Xylocaine interactions:

Browse all interactions between Xylocaine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and lidocaine hydrochloride (the active ingredients of Paracetamol and Xylocaine, respectively), and Paracetamol and Xylocaine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Paracetamol and Xylocaine.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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