Phenytoin sodium and Ibuprofen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Phenytoin sodium and Ibuprofen. Common interactions include drug toxicity among females and convulsion among males.
The phase IV clinical study analyzes what interactions people who take Phenytoin sodium and Ibuprofen have. It is created by eHealthMe based on reports of 109 people who take Phenytoin sodium and Ibuprofen from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
109 people who take Phenytoin sodium and Ibuprofen together, and have interactions are studied.
What is Phenytoin sodium?
Phenytoin sodium has active ingredients of phenytoin sodium. It is often used in epilepsy. eHealthMe is studying from 6,545 Phenytoin sodium users for its effectiveness, alternative drugs and more.
What is Ibuprofen?
Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,514 Ibuprofen users for its effectiveness, alternative drugs and more.
Number of Phenytoin sodium and Ibuprofen reports submitted per year:

Phenytoin sodium and Ibuprofen drug interactions by gender *:
Phenytoin sodium and Ibuprofen drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Phenytoin sodium and Ibuprofen?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Akasaka E, Kayo SJ, Nakano H, Ishii N, Hashimoto T, Sawamura D, "Diaminodiphenyl Sulfone-Induced Hemolytic Anemia and Alopecia in a Case of Linear IgA Bullous Dermatosis", Case reports in dermatology, 2014 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Phenytoin sodium (6,545 reports)
- Ibuprofen (210,514 reports)
Common Phenytoin sodium and Ibuprofen interactions:
- Drug ineffective: 9 reports
- Weakness: 8 reports
- Weight decreased: 6 reports
- Drowsiness: 4 reports
Browse all drug interactions of Phenytoin sodium and Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Phenytoin sodium side effects:
- Drug ineffective: 928 reports
- Seizures (abnormal excessive or synchronous neuronal activity in the brain): 386 reports
- Erythema multiforme (a type of hypersensitivity reaction): 263 reports
- Dizziness: 233 reports
- Rashes (redness): 225 reports
- Fever: 221 reports
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 206 reports
Browse all side effects of Phenytoin sodium:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Ibuprofen side effects:
- Pain: 17,474 reports
- Fatigue (feeling of tiredness): 15,323 reports
- Drug ineffective: 14,992 reports
- Headache (pain in head): 12,711 reports
- Rashes (redness): 11,328 reports
- Joint pain: 10,712 reports
- Nausea and vomiting: 10,601 reports
- Breathing difficulty: 10,304 reports
Browse all side effects of Ibuprofen:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Phenytoin sodium interactions:
- Phenytoin sodium and Levetiracetam: 522 reports
- Phenytoin sodium and Aspirin: 317 reports
- Phenytoin sodium and Carbamazepine: 286 reports
- Phenytoin sodium and Keppra: 277 reports
- Phenytoin sodium and Diazepam: 265 reports
- Phenytoin sodium and Gabapentin: 235 reports
- Phenytoin sodium and Omeprazole: 232 reports
- Phenytoin sodium and Loraz: 228 reports
- Phenytoin sodium and Valproic acid: 225 reports
- Phenytoin sodium and Furosemide: 208 reports
Browse all interactions between Phenytoin sodium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Ibuprofen interactions:
- Ibuprofen and Aspirin: 18,554 reports
- Ibuprofen and Prednisone: 17,888 reports
- Ibuprofen and Omeprazole: 16,600 reports
- Ibuprofen and Methotrexate: 14,412 reports
- Ibuprofen and Tylenol: 14,318 reports
- Ibuprofen and Gabapentin: 14,238 reports
- Ibuprofen and Lisinopril: 12,794 reports
- Ibuprofen and Tramadol: 11,947 reports
- Ibuprofen and Paracetamol: 11,571 reports
- Ibuprofen and Vitamin d: 11,317 reports
Browse all interactions between Ibuprofen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on phenytoin sodium and ibuprofen (the active ingredients of Phenytoin sodium and Ibuprofen, respectively), and Phenytoin sodium and Ibuprofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Phenytoin sodium and Ibuprofen.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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