Prilosec and Ambien drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Prilosec and Ambien. Common interactions include nausea among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people who take Prilosec and Ambien have. It is created by eHealthMe based on reports of 6,090 people who take Prilosec and Ambien from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
6,090 people who take Prilosec and Ambien together, and have interactions are studied.
What is Prilosec?
Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 168,989 Prilosec users for its effectiveness, alternative drugs and more.
What is Ambien?
Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 89,833 Ambien users for its effectiveness, alternative drugs and more.
Number of Prilosec and Ambien reports submitted per year:

Prilosec and Ambien drug interactions by gender *:
Prilosec and Ambien drug interactions by age *:
Common conditions people have *:
* Approximation only. Some reports may have incomplete information.
Do you take Prilosec and Ambien?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Prilosec and Ambien interactions:
- Pain: 866 reports
- Stress and anxiety: 772 reports
- Fatigue (feeling of tiredness): 722 reports
- Weakness: 623 reports
- Breathing difficulty: 592 reports
- Diarrhea: 580 reports
- Depression: 569 reports
- Back pain: 563 reports
Browse all drug interactions of Prilosec and Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Prilosec side effects:
- Chronic kidney disease: 50,470 reports
- Acute kidney failure: 18,775 reports
- Pain: 9,171 reports
- Fatigue (feeling of tiredness): 8,895 reports
- Drug ineffective: 8,739 reports
- Breathing difficulty: 7,478 reports
Browse all side effects of Prilosec:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Ambien side effects:
- Fatigue (feeling of tiredness): 7,733 reports
- Pain: 7,337 reports
- Stress and anxiety: 6,917 reports
- Insomnia (sleeplessness): 5,657 reports
- Headache (pain in head): 5,648 reports
Browse all side effects of Ambien:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Prilosec interactions:
- Prilosec and Nexium: 56,489 reports
- Prilosec and Prevacid: 50,473 reports
- Prilosec and Protonix: 44,471 reports
- Prilosec and Nexium 24hr: 33,749 reports
- Prilosec and Dexilant: 29,094 reports
- Prilosec and Prilosec otc: 28,856 reports
- Prilosec and Prevacid 24 hr: 27,132 reports
- Prilosec and Aspirin: 23,150 reports
- Prilosec and Lisinopril: 16,094 reports
- Prilosec and Prednisone: 13,664 reports
Browse all interactions between Prilosec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Ambien interactions:
- Ambien and Aspirin: 9,995 reports
- Ambien and Xanax: 9,196 reports
- Ambien and Prednisone: 7,399 reports
- Ambien and Synthroid: 6,889 reports
- Ambien and Lisinopril: 6,795 reports
- Ambien and Nexium: 6,634 reports
- Ambien and Gabapentin: 6,443 reports
- Ambien and Cymbalta: 6,361 reports
- Ambien and Lipitor: 6,159 reports
- Ambien and Lasix: 6,144 reports
Browse all interactions between Ambien and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on omeprazole and zolpidem tartrate (the active ingredients of Prilosec and Ambien, respectively), and Prilosec and Ambien (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Prilosec and Ambien.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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