Prinivil and Benadryl drug interactions - from FDA reports

Summary

Drug interactions are reported among people who take Prinivil and Benadryl together. This study is created by eHealthMe based on reports of 243 people who take Prinivil and Benadryl from FDA, and is updated regularly.



What's eHealthMe?

eHealthMe is a health data analysis company based in Mountain View, California. eHealthMe monitors and analyzes the outcomes of drugs and supplements that are currently on the market. The results are readily available to health care professionals and consumers.

eHealthMe has released original studies on market drugs and worked with leading universities and institutions such as IBM, London Health Science Centre, Mayo Clinic, Northwestern University and VA. eHealthMe studies have now been referenced in over 500 peer-reviewed medical publications.

How we gather our data?

Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). This information is aggregated and used to produce personalized reports that patients can reference.

The information that eHealthMe collects includes:

  • Side effects (including severity and how people recover from them)
  • Associated conditions or symptoms
  • Drug effectiveness
  • Demographic data regarding drug use

How the study uses the data?

The study is based on lisinopril and diphenhydramine hydrochloride (the active ingredients of Prinivil and Benadryl, respectively), and Prinivil and Benadryl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered.

What is Prinivil?

Prinivil has active ingredients of lisinopril. It is often used in high blood pressure. (latest outcomes from Prinivil 15,223 users)

What is Benadryl?

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 57,530 users)

How to use the study?

Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. It is recommended that patients use the information presented as a part of a broader decision-making process.


On Mar, 14, 2019

243 people who take Prinivil, Benadryl are studied.


Number of reports submitted per year:

Prinivil and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  1. Acute respiratory distress syndrome
  2. Cellulitis (infection under the skin)
  3. Drug ineffective
  4. Eosinophilic pneumonia (eosinophil accumulates in the lung)
  5. Fungal infection
  6. Impaired healing
  7. Injection site pruritus (severe itching at injection site)
  8. Injection site rash
  9. Injection site swelling
  10. Leukocytosis (increased white blood cells)
1 - 6 months:
  1. Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
  2. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  3. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
6 - 12 months:
  1. Dyspnoea (difficult or laboured respiration)
1 - 2 years:
  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. Rectal haemorrhage (bleeding from anus)
2 - 5 years:

n/a

5 - 10 years:
  1. Chest discomfort
  2. Chest pain
  3. Dyspnoea (difficult or laboured respiration)
  4. Hypersensitivity
  5. Hypokalaemia (low potassium)
  6. Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
  7. Swelling face
  8. Tachycardia (a heart rate that exceeds the range of 100 beats/min)
10+ years:

n/a

not specified:
  1. Atrial tachycardia (rhythm disturbance that arises in the atria)
  2. Atrioventricular block complete (heart block complete)
  3. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  4. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  5. Dry skin
  6. Exostosis (formation of new bone on the surface of a bone)
  7. Gingival pain (gum pain)
  8. Gingival ulceration (ulcer on gums)
  9. Haematocrit
  10. Hypoacusis (loss of hearing)

Most common drug interactions by gender *:

female:
  1. Headache (pain in head)
  2. Cardiac failure congestive
  3. Dizziness
  4. Dyspnoea (difficult or laboured respiration)
  5. Nausea (feeling of having an urge to vomit)
  6. Arthralgia (joint pain)
  7. Renal failure (kidney dysfunction)
  8. Vomiting
  9. Urinary tract infection
  10. Malaise (a feeling of general discomfort or uneasiness)
male:
  1. Fatigue (feeling of tiredness)
  2. Constipation
  3. Osteoporosis (bones weak and more likely to break)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Chest pain
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Dizziness
  9. Muscle spasms (muscle contraction)
  10. Osteonecrosis of jaw (death of bone of jaw)

Most common drug interactions by age *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:
  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Cardiac failure congestive
  3. Cholecystitis (infection of gallbladder)
  4. Influenza like illness
  5. Urinary tract infection
  6. Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Intracardiac thrombus (presence of a circumscribed mass with heart wall)
  9. Mass
  10. Multi-organ failure (multisystem organ failure)
30-39:
  1. Herpes simplex (herpes simplex is a common viral infection)
  2. Suicide attempt
  3. Anaemia (lack of blood)
  4. Grand mal convulsion (a type of generalized seizure that affects the entire brain)
  5. Overdose
  6. Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
  7. Abdominal discomfort
  8. Back pain
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Cardiomegaly (increased size of heart than normal)
40-49:
  1. Back pain
  2. Constipation
  3. Anxiety
  4. Cardiomegaly (increased size of heart than normal)
  5. Injury
  6. Pain
  7. Gait disturbance
  8. Intervertebral disc protrusion (spinal disc protrusion)
  9. Pain in extremity
  10. Dyspnoea (difficult or laboured respiration)
50-59:
  1. Intervertebral disc degeneration (spinal disc degeneration)
  2. Joint stiffness
  3. Pain
  4. Sinusitis (inflammation of sinus)
  5. Constipation
  6. Headache (pain in head)
  7. Urinary tract infection
  8. Fatigue (feeling of tiredness)
  9. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  10. Nausea (feeling of having an urge to vomit)
60+:
  1. Anaemia (lack of blood)
  2. Depression
  3. Haemoglobin decreased
  4. Hypoaesthesia (reduced sense of touch or sensation)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Constipation
  7. Cough
  8. Muscle spasms (muscle contraction)
  9. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  10. Gait disturbance

* Approximation only. Some reports may have incomplete information.


Do you take Prinivil and Benadryl?

You are not alone:




Related publications that referenced our studies


Results from eHealthMe (non-FDA) reports of taking Prinivil and Benadryl together

Drug effectiveness (drug is found to be effective) over time *:
Prinivil:
  • < 1 month: 0.0% (0 of 1 people)
  • 1 - 6 months: 0.0% (0 of 0 people)
  • 6 - 12 months: 0.0% (0 of 0 people)
  • 1 - 2 years: 0.0% (0 of 0 people)
  • 2 - 5 years: 0.0% (0 of 0 people)
  • 5 - 10 years: 0.0% (0 of 0 people)
  • 10+ years: 0.0% (0 of 0 people)
  • not specified: 0.0% (0 of 0 people)
Benadryl:
n/a
Drug effectiveness (drug is found to be effective) by gender *:
Prinivil:
  • female: 0.0% (0 of 1 people)
  • male: 0.0% (0 of 0 people)
Benadryl:
n/a
Drug effectiveness (drug is found to be effective) by age *:
Prinivil:
  • 0-1: 0.0% (0 of 0 people)
  • 2-9: 0.0% (0 of 0 people)
  • 10-19: 0.0% (0 of 0 people)
  • 20-29: 0.0% (0 of 0 people)
  • 30-39: 0.0% (0 of 0 people)
  • 40-49: 0.0% (0 of 0 people)
  • 50-59: 0.0% (0 of 0 people)
  • 60+: 0.0% (0 of 1 people)
Benadryl:
n/a
Race of the people *:
  • African American, Non-Hispanic: 0.0 %
  • American Indian/Alaska Native: 0.0 %
  • Asian: 0.0 %
  • Hispanic: 0.0 %
  • Native Hawaiians/Pacific Islanders: 0.0 %
  • Two or more races: 0.0 %
  • White, Non-Hispanic: 100 %

* Approximation only.


Related studies

Browse interactions by gender and age

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+


Interactions between Prinivil and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Interactions between Benadryl and drugs from A to Z
a b c d e f g h i j k l m n o p q r s t u v w x y z
Browse all drug interactions of Prinivil and Benadryl
a b c d e f g h i j k l m n o p q r s t u v w x y z

What would happen?

Predict new side effects and undetected conditions when you take Prinivil and Benadryl



FDA reports used in this study


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