Probiotic and Actemra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Probiotic and Actemra. Common interactions include hypoaesthesia among females and asthma among males.
The phase IV clinical study analyzes what interactions people who take Probiotic and Actemra have. It is created by eHealthMe based on reports of 33 people who take Probiotic and Actemra from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
33 people who take Probiotic and Actemra together, and have interactions are studied.
What is Probiotic?
Probiotic has active ingredients of bacillus coagulans. It is often used in irritable bowel syndrome. eHealthMe is studying from 22,017 Probiotic users for its effectiveness, alternative drugs and more.
What is Actemra?
Actemra has active ingredients of tocilizumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 97,637 Actemra users for its effectiveness, alternative drugs and more.
Number of Probiotic and Actemra reports submitted per year:

Common Probiotic and Actemra drug interactions by gender *:
female:
- Hypoaesthesia
- Lip swelling
- Muscle spasms
- Muscular weakness
- Myalgia
- Pancreatitis
- Psoriatic arthropathy
- Swelling
- Vomiting
- Oesophageal discomfort
male:
- Asthma
- Dysphonia
- Inflammation
- Infusion related reaction
- Injection site pruritus
- Joint swelling
- Nausea
- Oropharyngeal pain
- Pain
- Pruritus
Common Probiotic and Actemra drug interactions by age *:
0-1:
n/a
2-9:
- Mass
- Pain
10-19:
n/a
20-29:
- Alopecia
- Arthralgia
- Chills
- Fatigue
- Injection site pain
- Injection site urticaria
- Nausea
- Pelvic inflammatory disease
- Skin wound
- Sluggishness
30-39:
n/a
40-49:
n/a
50-59:
- Gait disturbance
- Gastroenteritis viral
- Haematochezia
- Hyperhidrosis
- Insomnia
- Limb injury
- Lower respiratory tract infection
- Migraine
- Mobility decreased
- Musculoskeletal stiffness
60+:
- Joint swelling
- Peripheral swelling
- Alopecia
- Arthralgia
- Arthritis
- Blood potassium decreased
- Carotid artery aneurysm
- Drug effect decreased
- Gingival pain
- Gingival swelling
Common conditions people have *:
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 18.18%
- Sinus Disorder (disease of sinus): 2 people, 6.06%
- Dry Eyes (lack of adequate tears): 2 people, 6.06%
- Bone Density Decreased: 2 people, 6.06%
- Blood Potassium Abnormal: 2 people, 6.06%
* Approximation only. Some reports may have incomplete information.
Do you take Probiotic and Actemra?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
Common Probiotic and Actemra interactions:
- Joint pain: 8 reports
- Joint swelling: 5 reports
Browse all drug interactions of Probiotic and Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Probiotic side effects:
- Fatigue (feeling of tiredness): 2,460 reports
- Diarrhea: 1,921 reports
- Headache (pain in head): 1,390 reports
- Dizziness: 1,216 reports
- Weakness: 1,148 reports
- Rashes (redness): 1,083 reports
- Pain: 1,036 reports
Browse all side effects of Probiotic:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Actemra side effects:
- Drug ineffective: 40,430 reports
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints): 25,436 reports
- Pain: 20,065 reports
- Joint pain: 16,945 reports
- Joint swelling: 15,891 reports
- Fatigue (feeling of tiredness): 13,817 reports
- Rashes (redness): 13,617 reports
Browse all side effects of Actemra:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Probiotic interactions:
- Probiotic and Vitamin d: 5,762 reports
- Probiotic and Aspirin: 4,562 reports
- Probiotic and Fish oil: 3,248 reports
- Probiotic and Vitamin d3: 2,909 reports
- Probiotic and Vitamin b12: 2,873 reports
- Probiotic and Vitamin c: 2,833 reports
- Probiotic and Multivitamin: 2,821 reports
- Probiotic and Magnesium: 2,650 reports
- Probiotic and Calcium: 2,604 reports
- Probiotic and Omeprazole: 2,331 reports
Browse all interactions between Probiotic and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Actemra interactions:
- Actemra and Methotrexate: 55,684 reports
- Actemra and Enbrel: 39,076 reports
- Actemra and Orencia: 38,141 reports
- Actemra and Humira: 32,696 reports
- Actemra and Prednisone: 29,225 reports
- Actemra and Arava: 26,672 reports
- Actemra and Sulfasalazine: 26,117 reports
- Actemra and Remicade: 22,165 reports
- Actemra and Xeljanz: 20,704 reports
- Actemra and Leflunomide: 20,310 reports
Browse all interactions between Actemra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on bacillus coagulans and tocilizumab (the active ingredients of Probiotic and Actemra, respectively), and Probiotic and Actemra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Probiotic and Actemra.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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