Profen and Saccharomyces drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Profen and Saccharomyces. Common interactions include dehydration among females and blood creatine phosphokinase increased among males.
The phase IV clinical study analyzes what interactions people who take Profen and Saccharomyces have. It is created by eHealthMe based on reports of 33 people who take Profen and Saccharomyces from the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.
33 people who take Profen and Saccharomyces together, and have interactions are studied.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 210,455 Profen users for its effectiveness, alternative drugs and more.
What is Saccharomyces?
Saccharomyces has active ingredients of saccharomyces boulardii. eHealthMe is studying from 897 Saccharomyces users for its effectiveness, alternative drugs and more.
Number of Profen and Saccharomyces reports submitted per year:

Common Profen and Saccharomyces drug interactions by gender *:
female:
- Dehydration
- Dementia
- Device related infection
- Dizziness
- Drug withdrawal syndrome
- Duodenitis
- Enterococcal infection
- Fall
- Fear
- Fluid retention
male:
- Blood creatine phosphokinase increased
- Infusion related reaction
- Flank pain
- Hyperkalaemia
- Hypertension
- Malignant neoplasm progression
- Mental status changes
- Metastases to liver
- Peripheral swelling
- Pleural effusion
Common Profen and Saccharomyces drug interactions by age *:
0-1:
n/a
2-9:
n/a
10-19:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Colitis
- Drug-induced liver injury
- Ileitis
- Colitis ulcerative
- Drug ineffective
- Fall
- Renal cancer
20-29:
- Paraesthesia
- Abdominal pain upper
- Anxiety
- Autoimmune disorder
- Diarrhoea
- Fatigue
- Fear
- Headache
- Hyperhidrosis
- Injury
30-39:
- Necrosis ischaemic
- Pneumonia streptococcal
- Septic shock
- Urinary tract infection
- Beta haemolytic streptococcal infection
- Loss of consciousness
40-49:
- Asthenia
- Contusion
- Heart rate decreased
- Heparin-induced thrombocytopenia
- Hepatic failure
- Hypersensitivity
- Lethargy
- Muscle disorder
- Renal failure
- Adverse event
50-59:
- Blood creatine phosphokinase increased
- Infusion related reaction
- Ligament rupture
- Arrhythmia
- Abdominal distension
- Abdominal pain
- Diarrhoea
- Gastritis
60+:
- Hypertension
- Acute respiratory failure
- Hyperlipidaemia
- Hyperosmolar state
- Hypotension
- Ileus paralytic
- Metabolic acidosis
- Peptic ulcer
- Pleural effusion
- Renal failure acute
Common conditions people have *:
- Insomnia (sleeplessness): 13 people, 39.39%
- Malignant Melanoma (skin cancer rises from melancytes): 4 people, 12.12%
- Pneumonia: 4 people, 12.12%
- Blood Uric Acid Increased: 3 people, 9.09%
- Nasopharyngitis (inflammation of the nasopharynx): 3 people, 9.09%
- Joint Pain: 3 people, 9.09%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 9.09%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 3 people, 9.09%
- Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 9.09%
- Gastric Ulcer (stomach ulcer): 3 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Profen and Saccharomyces?
Personalize this study to your gender and ageHow to use the study?
You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.
Related publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Related studies
Alternative drugs to, pros and cons of the 2 drugs:
- Profen (210,455 reports)
- Saccharomyces (897 reports)
Browse all drug interactions of Profen and Saccharomyces:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Profen side effects:
- Pain: 17,497 reports
- Fatigue (feeling of tiredness): 15,338 reports
- Drug ineffective: 14,999 reports
- Headache (pain in head): 13,179 reports
- Rashes (redness): 11,357 reports
- Joint pain: 10,715 reports
- Breathing difficulty: 10,286 reports
- Indigestion: 10,029 reports
Browse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Saccharomyces side effects:
- Diarrhea: 131 reports
Browse all side effects of Saccharomyces:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Profen interactions:
- Profen and Aspirin: 18,557 reports
- Profen and Prednisone: 17,910 reports
- Profen and Omeprazole: 16,610 reports
- Profen and Methotrexate: 14,414 reports
- Profen and Tylenol: 14,335 reports
- Profen and Gabapentin: 14,241 reports
- Profen and Lisinopril: 12,796 reports
- Profen and Tramadol: 11,969 reports
- Profen and Paracetamol: 11,573 reports
- Profen and Vitamin d: 11,322 reports
Browse all interactions between Profen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon Saccharomyces interactions:
- Saccharomyces and Furosemide: 134 reports
- Saccharomyces and Omeprazole: 130 reports
- Saccharomyces and Pantoprazole: 110 reports
- Saccharomyces and Aspirin: 106 reports
Browse all interactions between Saccharomyces and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and saccharomyces boulardii (the active ingredients of Profen and Saccharomyces, respectively), and Profen and Saccharomyces (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study. Patients in the study may take other drugs besides Profen and Saccharomyces.
Who is eHealthMe?
With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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